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公开(公告)号:US3933873A
公开(公告)日:1976-01-20
申请号:US477712
申请日:1974-06-10
Applicant: Richard F. Love , Kablaoui Mahmoud S. , Roger G. Duranleau
Inventor: Richard F. Love , Kablaoui Mahmoud S. , Roger G. Duranleau
IPC: C07C205/51 , C07D201/02 , C07D201/10 , C07C99/00
CPC classification number: C07D201/02 , C07C201/12 , C07C201/14 , C07C227/04 , C07C227/20 , C07D201/10 , C07C2101/20
Abstract: A method for preparing omega-aminoalkanoic acids by the steps of (1) nitro-oxidizing a cycloalkene to a cyclic alpha-nitroketone, (2) cleaving and esterifying a cyclic alpha-nitroketone with an alcohol to form an alkyl omega-nitroester, (3) catalytically hydrogenating the nitroester to an aminoester and (4) hydrolyzing the aminoester to an aminoalkanoic acid.
Abstract translation: 通过以下步骤制备ω-氨基链烷酸的方法:(1)将环烯烃硝基氧化成环状α-硝基酮,(2)用醇裂解和酯化环状α-硝基酮以形成烷基ω-硝基酯( 3)将硝酯催化氢化成氨基酯,和(4)将氨基酯水解成氨基链烷酸。