公开(公告)号：US08039454B2

公开(公告)日：2011-10-18

申请号：US12084959

申请日：2006-11-28

Applicant: Genhui Chen ,  Bin Li ,  John M. Webster ,  Kaiji Hu ,  Jianxiong Li

Inventor： Genhui Chen ,  Bin Li ,  John M. Webster ,  Kaiji Hu ,  Jianxiong Li

IPC: C07D269/00 ,  A61K31/33 ,  A61P31/00 ,  A61P35/00

CPC classification number: C07D269/00

Abstract: The invention is drawn to novel macrolide compounds of formula I having antibiotic and antineoplastic activities, useful as medicaments and/or agrochemicals for microorganism infections, in particularly for infectious diseases involving drug-resistant Staphylococcus, and for treatment of human and animal cancers.

Abstract translation: 本发明涉及具有抗生素和抗肿瘤活性的新型的具有抗生素和抗肿瘤活性的大环内酯类化合物，可用作微生物感染的药物和/或农药，特别是涉及耐药葡萄球菌的感染性疾病，以及用于治疗人类和动物癌症。

公开(公告)号：US20090264644A1

公开(公告)日：2009-10-22

申请号：US12084959

申请日：2006-11-28

Applicant: Genhui Chen ,  Bin Li ,  John M. Webster ,  Kaiji Hu ,  Jianxiong Li

Inventor： Genhui Chen ,  Bin Li ,  John M. Webster ,  Kaiji Hu ,  Jianxiong Li

IPC: C07D269/00 ,  A61P31/00 ,  A61P35/00

CPC classification number: C07D269/00

Abstract: The invention is drawn to novel macrolide compounds of formula I having antibiotic and antineoplastic activities, useful as medicaments and/or agrochemicals for microorganism infections, in particularly for infectious diseases involving drug-resistant Staphylococcus, and for treatment of human and animal cancers.

Abstract translation: 本发明涉及具有抗生素和抗肿瘤活性的新型的具有抗生素和抗肿瘤活性的大环内酯类化合物，可用作微生物感染的药物和/或农药，特别是涉及耐药性葡萄球菌的感染性疾病，以及用于治疗人和动物癌症。