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1.发明申请Hepatitis B variants with reduced sensitivity to therapeutic compounds, their detection and uses thereof 有权对治疗性化合物的敏感性降低的乙型肝炎变体，其检测和用途公开(公告)号：US20090253123A1
公开(公告)日：2009-10-08
申请号：US12384132
申请日：2009-03-31
CPC分类号： C12Q1/706 , A61K38/00 , C07K14/005
摘要： The present invention is a diagnostic kit and materials for: 1) the prediction of the long-term response of a chronic hepatitis B virus (HBV) carrier to treatment with nucleoside/nucleotide analogue, or their combination; 2) the detection of HBV variants that exhibit reduced reactivity to antibody detection; 3) the detection of HBV variants in the precore/core region that negatively affect the course of liver disease; 4) the identification of the HBV genotype.
摘要翻译： 本发明是一种诊断试剂盒和材料，用于：1）预测慢性乙型肝炎病毒（HBV）载体对用核苷/核苷酸类似物或其组合进行治疗的长期反应; 2）对抗体检测反应性降低的HBV变体的检测; 3）检测对肝脏疾病过程有负面影响的前核/核心区域HBV变异; 4）鉴定HBV基因型。
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公开(公告)号：US09879330B2
公开(公告)日：2018-01-30
申请号：US12384132
申请日：2009-03-31
IPC分类号： C12Q1/70 , C07K14/005 , A61K38/00
CPC分类号： C12Q1/706 , A61K38/00 , C07K14/005
摘要： The present invention is a diagnostic kit and materials for: 1) the prediction of the long-term response of a chronic hepatitis B virus (HBV) carrier to treatment with nucleoside/nucleotide analog, or their combination; 2) the detection of HBV variants that exhibit reduced reactivity to antibody detection; 3) the detection of HBV variants in the precore/core region that negatively affect the course of liver disease; 4) the identification of the HBV genotype.
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