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公开(公告)号：US20090130234A1
公开(公告)日：2009-05-21
申请号：US12089762
申请日：2006-10-10
申请人： Peter Literati Nagy , Zsolt Lohinai , Kalman Tory , Attila Kolonics , Agnes Keri , Orsolya Rigo , Andras Huszak , Balazs Zahonyi , Sandor Bernath , Laszlo Vigh , Tibor Bodnar , Jonos Egri
发明人： Peter Literati Nagy , Zsolt Lohinai , Kalman Tory , Attila Kolonics , Agnes Keri , Orsolya Rigo , Andras Huszak , Balazs Zahonyi , Sandor Bernath , Laszlo Vigh , Tibor Bodnar , Jonos Egri
IPC分类号： A61K36/28
CPC分类号： A61K36/28 , A61K9/0063 , A61K9/0095 , A61K9/19 , A61K9/2027 , A61K9/4866
摘要： The invention refers to the use of an extract of a part of a Solidago species, wherein said part has grown above the earth, or the solid residue remaining after the removal of the solvent content of the extract as the active agent for the preparation of a pharmaceutical composition suitable for the treatment of diabetic periodontitis.
摘要翻译： 本发明涉及使用一部分一氧化碳物质的提取物，其中所述部分已经在地球上生长，或者在除去提取物的溶剂含量后残留的固体残余物作为制备 适用于治疗糖尿病牙周炎的药物组合物。
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公开(公告)号：US20070281972A1
公开(公告)日：2007-12-06
申请号：US11629280
申请日：2005-06-13
IPC分类号： A61K31/445 , A61P1/14
CPC分类号： A61K31/455
摘要： The invention refers to the use of O-(3-piperidino-2-hydroxypropyl)nicotinic amidoxime or a pharmaceutically suitable acid addition salt thereof for the preparation of a pharmaceutical composition that restores and/or enhances the activity of the neuronal nitric oxide synthase enzyme.
摘要翻译： 本发明涉及O-（3-哌啶子基-2-羟丙基）烟碱偕胺肟或其药学上合适的酸加成盐用于制备恢复和/或增强神经元一氧化氮合酶的活性的药物组合物 。
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公开(公告)号：US20090054487A1
公开(公告)日：2009-02-26
申请号：US11629279
申请日：2005-06-13
IPC分类号： A61K31/4545 , C07D401/02
CPC分类号： A61K31/455
摘要： The invention refers to the use of O-(3-piperidino-2-hydroxypropyl)nicotinic amidoxime or a pharmaceutically suitable acid addition salt thereof for the preparation of a pharmaceutical composition increasing the mitochondrial genesis.
摘要翻译： 本发明涉及O-（3-哌啶子基-2-羟丙基）烟碱偕胺肟或其药学上合适的酸加成盐在制备增加线粒体发生的药物组合物中的用途。
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4.发明申请Dose Reduction of a Cannabinoid CB1 Receptor Antagonist in the Treatment of Overweight or Obesity 审中-公开大麻素CB1受体拮抗剂治疗超重或肥胖的剂量减少公开(公告)号：US20090281143A1
公开(公告)日：2009-11-12
申请号：US12331890
申请日：2008-12-10
申请人： Peter Literati Nagy , Zoltan Szilvassy , Kalman Tory , Attila Kolonics , Sandor Bernath , Laszlo Vigh , Jesse Roth , G. Alexander Fleming , Michael Brownstein , Janos Egri
发明人： Peter Literati Nagy , Zoltan Szilvassy , Kalman Tory , Attila Kolonics , Sandor Bernath , Laszlo Vigh , Jesse Roth , G. Alexander Fleming , Michael Brownstein , Janos Egri
IPC分类号： A61K31/4545 , A61P3/04
CPC分类号： A61K31/454 , A61K31/4545 , A61K45/06 , A61K2300/00
摘要： O-(3-Piperidino-2-hydroxy-1-propyl)-nicotinic amidoxime or a pharmaceutically acceptable acid addition salt thereof is administered to patients suffering from overweight or obesity and treated with a cannabinoid CB1 receptor antagonist such as rimonabant to reduce overweight or obesity and, preferably, reduce one or more unfavourable psychiatric side effects of the cannabinoid CB1 receptor antagonist.
摘要翻译： 向患有超重或肥胖症的患者施用O-（3-哌啶子基-2-羟基-1-丙基） - 烟酰胺偕胺肟或其药学上可接受的酸加成盐，并用大麻素CB1受体拮抗剂如利莫那班治疗以减少超重或 肥胖症，并且优选地减少大麻素CB1受体拮抗剂的一种或多种不利的精神病学副作用。
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公开(公告)号：US20090149498A1
公开(公告)日：2009-06-11
申请号：US12320819
申请日：2009-02-05
IPC分类号： A61K31/455 , A61P1/04 , A61P1/16 , A61P1/18
CPC分类号： A61K31/455
摘要： The invention refers to the use of O-(3-piperidino-2-hydroxypropyl)nicotinic amidoxime or a pharmaceutically suitable acid addition salt thereof for the preparation of a pharmaceutical composition that restores and/or enhances the activity of the neuronal nitric oxide synthase enzyme.
摘要翻译： 本发明涉及O-（3-哌啶子基-2-羟丙基）烟碱偕胺肟或其药学上合适的酸加成盐用于制备恢复和/或增强神经元一氧化氮合酶的活性的药物组合物 。
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公开(公告)号：US20080108673A1
公开(公告)日：2008-05-08
申请号：US11687945
申请日：2007-03-19
申请人： Peter Literati Nagy , Zoltan Szilvassy , Kalman Tory , Laszlo Vigh , Kalman Takacs , Jozsef Mandl , Balazs Sumegi , Sandor Bernath , Attila Kolonics , Gabor Balogh , Janos Egri
发明人： Peter Literati Nagy , Zoltan Szilvassy , Kalman Tory , Laszlo Vigh , Kalman Takacs , Jozsef Mandl , Balazs Sumegi , Sandor Bernath , Attila Kolonics , Gabor Balogh , Janos Egri
CPC分类号： A61K31/4545 , Y10S514/909
摘要： O-(3-piperidino-2-hydroxypropyl)-nicotinic amidoxime or a pharmaceutically suitable acid addition salt thereof (BGP-15) can be used for the prevention or reduction of weight gain or the reduction of the rate of body weight.
摘要翻译： O-（3-哌啶子基-2-羟丙基） - 烟酰胺肟或其药学上合适的酸加成盐（BGP-15）可以用于预防或减轻体重增加或减轻体重。
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公开(公告)号：US20090214677A1
公开(公告)日：2009-08-27
申请号：US11991362
申请日：2006-08-30
申请人： Péter Literati Nagy , Kalman Tory , Attila Kolonics , Agnes Keri , Lajos Laszlo , Laszlo Jaszlits , Agnes Bajza , Sandor Bernath , Laszlo Vigh , Tibor Bodnar , Janos Egri
发明人： Péter Literati Nagy , Kalman Tory , Attila Kolonics , Agnes Keri , Lajos Laszlo , Laszlo Jaszlits , Agnes Bajza , Sandor Bernath , Laszlo Vigh , Tibor Bodnar , Janos Egri
CPC分类号： A61K36/28
摘要： An extract of a part of a Solidago species, wherein said part has grown above the earth, or the solid residue remaining after the removal of the solvent content of the extract as the active ingredient is used for the regeneration of the organism of a mammal after long-lasting immobilization, anorexia, states following a disease or accompanied by weight loss as well as for muscle development or muscle growth during muscle developing training, treatment of muscular strain and adaptation to high-altitude as well as for the prevention or treatment of neurodegenerative diseases and/or motility disorders of the gastrointestinal system.
摘要翻译： 一部分单体提取物，其中所述部分已经生长在地球上方，或者在除去作为活性成分的溶剂含量后残留的固体残余物用于哺乳动物的生物再生后 持续的固定化，厌食症，疾病状态或伴随体重减轻以及肌肉发育训练期间的肌肉发育或肌肉生长，肌肉应变治疗和适应高海拔以及预防或治疗神经变性 胃肠系统的疾病和/或运动障碍。
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8.发明申请Prevention of obesity in antipsychotic, antidepressant and antiepileptic medication 审中-公开预防抗精神病药，抗抑郁药和抗癫痫药物中的肥胖公开(公告)号：US20080108602A1
公开(公告)日：2008-05-08
申请号：US11687954
申请日：2007-03-19
申请人： Peter Literati Nagy , Jesse Roth , Zoltan Szilvassy , Kalman Tory , Mike Brownstein , Kalman Takacs , Laszlo Vigh , Jozsef Mandi , Balazs Sumegi , Sandor Bernath , Attila Kolonics , Gabor Balogh , Janos Egri
发明人： Peter Literati Nagy , Jesse Roth , Zoltan Szilvassy , Kalman Tory , Mike Brownstein , Kalman Takacs , Laszlo Vigh , Jozsef Mandi , Balazs Sumegi , Sandor Bernath , Attila Kolonics , Gabor Balogh , Janos Egri
IPC分类号： A61K31/445 , A61K31/519 , A61K31/551 , A61P3/04
CPC分类号： A61K31/4545 , A61K31/19 , A61K31/40 , A61K31/519 , A61K31/551 , A61K31/5513 , A61K31/554 , A61K45/06 , A61K2300/00
摘要： O-(3-piperidino-2-hydroxypropyl)-nicotinic amidoxime or a pharmaceutically suitable acid addition salt thereof (BGP-15) can be used for the prevention or reduction of weight gain or obesity in a patient treated with an antipsychotic drug or an antidepressant drug or an antiepileptic drug.
摘要翻译： O-（3-哌啶子基-2-羟丙基） - 烟酰胺肟或其药学上合适的酸加成盐（BGP-15）可以用于预防或减轻用抗精神病药物治疗的患者体重增加或肥胖， 抗抑郁药或抗癫痫药。
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公开(公告)号：US4806685A
公开(公告)日：1989-02-21
申请号：US825777
申请日：1986-01-31
申请人： Gizella Abraham , Tibor Horvath , Lajos Toldy , Janos Borvendeg , Endre Csanyi , Eva Kiss , Ilona S. nee Hermann , Kalman Tory
发明人： Gizella Abraham , Tibor Horvath , Lajos Toldy , Janos Borvendeg , Endre Csanyi , Eva Kiss , Ilona S. nee Hermann , Kalman Tory
IPC分类号： C07C43/225 , C07C43/313 , C07D295/092 , C07D303/22 , C07D303/26 , C07C93/06
CPC分类号： C07D295/088 , C07C247/00 , C07C43/225 , C07C43/313 , C07D303/22 , C07D303/26
摘要： A novel 1,1,2-triphenylpropene derivative, namely: ##STR1## acts on the endocrine system of rats. It exerts oestrogenic or antioestrogenic effects of varying strength in rats, and furthermore inhibits the growth of the mammary tumor induced by 7,12-dimethyl-benz(a)anthracene in rats.
摘要翻译： 一种新的1,1,2-三苯基丙烯衍生物，即：
作用于大鼠的内分泌系统。 它在大鼠中发挥不同强度的雌激素或抗雌激素作用，进而抑制7,12-二甲基 - 苯并（a）蒽在大鼠中诱导的乳腺肿瘤的生长。
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