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公开(公告)号：US08212024B2
公开(公告)日：2012-07-03
申请号：US12089821
申请日：2006-10-12
Applicant: Udayampalayam Palanisamy Senthilkumar , Kanagaraj Suresh Kumar , Singaravel Mohan , Lakshminarayanan Arunkumar , Bakthavachalam Ananthan
Inventor： Udayampalayam Palanisamy Senthilkumar , Kanagaraj Suresh Kumar , Singaravel Mohan , Lakshminarayanan Arunkumar , Bakthavachalam Ananthan
IPC: C07D501/36 , A61K31/546
CPC classification number: C07D501/36
Abstract: The present invention relates to novel polymorph of Ceftiofur sodium as a crystalline product. The present invention also provides a process for the preparation of crystalline Ceftiofur sodium of formula (I).
Abstract translation: 本发明涉及头孢噻呋钠作为结晶产物的新型多晶型物。 本发明还提供了制备式（I）的结晶头孢噻呋钠的方法。
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2.发明申请Improved Process For the Preparation of Cephalosporin Antibiotic Intermediate 审中-公开改进制备头孢菌素抗生素中间体的方法公开(公告)号：US20100261897A1
公开(公告)日：2010-10-14
申请号：US11794735
申请日：2006-01-16
IPC: C07D501/18
CPC classification number: C07D501/18 , C07D501/04
Abstract: The present invention relates to a process for the production of cephalosporin antibiotic intermediate of formula (I). More particularly relates to the preparation of the compound of formula (I) using a solvent medium selected from the group consisting of decalin (decahydronapthalene), hexane, cyclohexene, tetralin, petroleum ether, wherein X represents HI, HCI, H2SO4 and the like. The compound of formula (I) is an important intermediate in the preparation of Cefepime.
Abstract translation: 本发明涉及制备式（I）的头孢菌素抗生素中间体的方法。 更具体地涉及使用选自十氢萘（十氢萘），己烷，环己烯，四氢化萘，石油醚，其中X代表HI，HCl，H 2 SO 4等的溶剂介质制备式（I）化合物。 式（I）化合物是头孢吡肟制剂中的重要中间体。
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公开(公告)号：US20080221076A1
公开(公告)日：2008-09-11
申请号：US12089821
申请日：2006-10-12
Applicant: Udayampalayam Palanisamy Senthilkumar , Kanagaraj Suresh Kumar , Singaravel Mohan , Lakshminarayanan Arunkumar , Bakthavachalam Ananthan
Inventor： Udayampalayam Palanisamy Senthilkumar , Kanagaraj Suresh Kumar , Singaravel Mohan , Lakshminarayanan Arunkumar , Bakthavachalam Ananthan
IPC: A61K31/546 , C07D501/02 , C07D501/16 , A61P31/00
CPC classification number: C07D501/36
Abstract: The present invention relates to novel polymorph of Ceftiofur sodium as a crystalline product. The present invention also provides a process for the preparation of crystalline Ceftiofur sodium of formula (I).
Abstract translation: 本发明涉及头孢噻呋钠作为结晶产物的新型多晶型物。 本发明还提供了制备式（I）的结晶头孢噻呋钠的方法。
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