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公开(公告)号:US07419663B2
公开(公告)日:2008-09-02
申请号:US10964263
申请日:2004-10-12
申请人: Avi Ashkenazi , Karim Yussef Helmy , Sherman Fong , Audrey Goddard , Austin L. Gurney , Kenneth James Katschke, Jr. , Mary A. Napier , Daniel Tumas , Menno Van Lookeren , William I. Wood
发明人: Avi Ashkenazi , Karim Yussef Helmy , Sherman Fong , Audrey Goddard , Austin L. Gurney , Kenneth James Katschke, Jr. , Mary A. Napier , Daniel Tumas , Menno Van Lookeren , William I. Wood
IPC分类号: A61K39/00 , A61K39/395
CPC分类号: C07K14/70503 , A61K2039/505 , C07K16/2803 , C07K2317/76 , C07K2319/30 , Y10S424/809 , Y10S424/81
摘要: The present invention concerns a recently discovered macrophage specific receptor, STIgMA, and its use in the treatment of complement-associated disorders.
摘要翻译: 本发明涉及最近发现的巨噬细胞特异性受体STIgMA及其在补体相关疾病的治疗中的应用。
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公开(公告)号:US20120189626A1
公开(公告)日:2012-07-26
申请号:US13327523
申请日:2011-12-15
申请人: Avi Ashkenazi , Karim Yussef Helmy , Sherman Fong , Audrey Goddard , Austin L. Gurney , Kenneth James Katschke, JR. , Menno Van Lookeren , William I. Wood
发明人: Avi Ashkenazi , Karim Yussef Helmy , Sherman Fong , Audrey Goddard , Austin L. Gurney , Kenneth James Katschke, JR. , Menno Van Lookeren , William I. Wood
IPC分类号: A61K39/395 , A61P17/00 , A61P17/06 , A61P37/08 , A61P41/00 , A61P27/02 , A61P13/12 , A61P11/06 , A61P3/10 , A61P29/00 , A61P1/00 , A61P37/02 , A61P7/06 , A61P25/00 , A61P31/14 , A61P31/12 , A61P11/00 , A61P9/00 , A61P19/02
CPC分类号: A61K38/177 , A61K38/17 , A61K38/1709 , A61K2039/505 , C07K14/705 , C07K16/28 , C07K2317/77 , C07K2319/30 , Y02A50/463 , A61K2300/00
摘要: The present invention concerns a recently discovered macrophage specific receptor, CRIg, and its use in the treatment of complement-associated disorders.
摘要翻译: 本发明涉及最近发现的巨噬细胞特异性受体CRIg及其在补体相关疾病的治疗中的应用。
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公开(公告)号:US08088386B2
公开(公告)日:2012-01-03
申请号:US11159919
申请日:2005-06-22
申请人: Avi Ashkenazi , Karim Yussef Helmy , Sherman Fong , Audrey Goddard , Austin L. Gurney , Kenneth James Katschke, Jr. , Menno Van Lookeren , William I. Wood
发明人: Avi Ashkenazi , Karim Yussef Helmy , Sherman Fong , Audrey Goddard , Austin L. Gurney , Kenneth James Katschke, Jr. , Menno Van Lookeren , William I. Wood
IPC分类号: A61K39/395
CPC分类号: A61K38/177 , A61K38/17 , A61K38/1709 , A61K2039/505 , C07K14/705 , C07K16/28 , C07K2317/77 , C07K2319/30 , Y02A50/463 , A61K2300/00
摘要: The present invention concerns a recently discovered macrophage specific receptor, CRIg, and its use in the treatment of complement-associated disorders.
摘要翻译: 本发明涉及最近发现的巨噬细胞特异性受体CRIg及其在补体相关疾病的治疗中的应用。
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公开(公告)号:US08007798B2
公开(公告)日:2011-08-30
申请号:US11249825
申请日:2005-10-12
申请人: Avi Ashkenazi , Karim Yussef Helmy , Sherman Fong , Audrey Goddard , Austin L. Gurney , Kenneth James Katschke, Jr. , Menno Van Lookeren , William I. Wood
发明人: Avi Ashkenazi , Karim Yussef Helmy , Sherman Fong , Audrey Goddard , Austin L. Gurney , Kenneth James Katschke, Jr. , Menno Van Lookeren , William I. Wood
IPC分类号: A61K39/395
CPC分类号: G01N33/57484 , A61K38/00 , C07K14/705 , C07K16/28 , C07K2317/24 , C07K2319/30 , G01N33/6893
摘要: The present invention concerns a recently discovered macrophage specific receptor, CRIg, and its use in the prevention and treatment of complement-associated disorders, including complement-associated eye conditions, such as age-related macular degeneration (AMD) and choroidal neovascularization (CNV).
摘要翻译: 本发明涉及最近发现的巨噬细胞特异性受体CRIg及其在预防和治疗补体相关疾病(包括补体相关性眼病)如年龄相关性黄斑变性(AMD)和脉络膜新生血管形成(CNV)中的用途。 。
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