公开(公告)号：US20110062630A1

公开(公告)日：2011-03-17

申请号：US12993580

申请日：2009-05-21

申请人： Yosuke Honda ,  Kazuhiro Oobae

发明人： Yosuke Honda ,  Kazuhiro Oobae

IPC分类号： A61K31/167 ,  A61P29/00 ,  A23L1/308 ,  B32B5/16 ,  F26B3/06 ,  B29C43/00

CPC分类号： A61K47/38 ,  A23L29/262 ,  A23V2002/00 ,  A61K8/731 ,  A61K9/14 ,  A61K9/2054 ,  A61K9/2095 ,  A61K51/1241 ,  C08J3/12 ,  C08J2301/02 ,  C08L1/02 ,  Y10T428/2982 ,  A23V2250/5108

摘要： With regard to compositions derived from active ingredients and other additives in medical, food and industrial fields, there have been problems that the active ingredients cannot be uniformly mixed, and that the active ingredients become segregated and lose uniformity as the active ingredients undergo transport, input, and filling processes. There is provided a cellulose powder which improves the uniformity of compositions containing active ingredients or other additives to prevent segregation of the active ingredients, wherein the cellulose powder contains cellulose I type crystals, has an average particle diameter of less than 30 μm, a powder density of 0.1 to 0.45 g/cm3, a tapping density of 0.1 to 0.5 g/cm3, a repose angle of 35 to 50°, a specific surface of more than or equal to 0.1 m2/g and less than 20 m2/g, an internal friction angle of 36 to 42°, and is a cellulose powder including a secondary flocculation structure in which primary particles are flocculated.

摘要翻译： 关于在医疗，食品和工业领域中衍生自活性成分和其它添加剂的组合物，存在的问题是活性成分不能均匀混合，并且活性成分变得分离并且随着活性成分经过运输而失去均匀性 和填充过程。 提供一种改善含有活性成分或其它添加剂的组合物的均匀性的纤维素粉末，以防止活性成分的偏析，其中纤维素粉末含有纤维素I型晶体，平均粒径小于30μm，粉末密度 0.1〜0.45g / cm 3，攻丝密度为0.1〜0.5g / cm 3，休止角为35〜50°，比表面积大于等于0.1m 2 / g且小于20m 2 / g， 内摩擦角为36〜42°，是含有一次粒子絮凝的二次絮凝结构的纤维素粉末。

公开(公告)号：US09132195B2

公开(公告)日：2015-09-15

申请号：US12993580

申请日：2009-05-21

申请人： Yosuke Honda ,  Kazuhiro Oobae

发明人： Yosuke Honda ,  Kazuhiro Oobae

IPC分类号： A61K9/20 ,  A61K47/38 ,  A23L1/0534 ,  A61K8/73 ,  C08J3/12 ,  C08L1/02 ,  A61K51/12 ,  A61K9/14

CPC分类号： A61K47/38 ,  A23L29/262 ,  A23V2002/00 ,  A61K8/731 ,  A61K9/14 ,  A61K9/2054 ,  A61K9/2095 ,  A61K51/1241 ,  C08J3/12 ,  C08J2301/02 ,  C08L1/02 ,  Y10T428/2982 ,  A23V2250/5108

摘要： With regard to compositions derived from active ingredients and other additives in medical, food and industrial fields, there have been problems that the active ingredients cannot be uniformly mixed, and that the active ingredients become segregated and lose uniformity as the active ingredients undergo transport, input, and filling processes. There is provided a cellulose powder which improves the uniformity of compositions containing active ingredients or other additives to prevent segregation of the active ingredients, wherein the cellulose powder contains cellulose I type crystals, has an average particle diameter of less than 30 μm, a powder density of 0.1 to 0.45 g/cm3, a tapping density of 0.1 to 0.5 g/cm3, a repose angle of 35 to 50°, a specific surface of more than or equal to 0.1 m2/g and less than 20 m2/g, an internal friction angle of 36 to 42°, and is a cellulose powder including a secondary flocculation structure in which primary particles are flocculated.

摘要翻译： 关于在医疗，食品和工业领域中衍生自活性成分和其它添加剂的组合物，存在的问题是活性成分不能均匀混合，并且活性成分变得分离并且随着活性成分经过运输而失去均匀性 和填充过程。 提供一种改善含有活性成分或其它添加剂的组合物的均匀性的纤维素粉末，以防止活性成分的偏析，其中纤维素粉末含有纤维素I型晶体，平均粒径小于30μm，粉末密度 0.1〜0.45g / cm 3，攻丝密度为0.1〜0.5g / cm 3，休止角为35〜50°，比表面积大于等于0.1m 2 / g且小于20m 2 / g， 内摩擦角为36〜42°，是含有一次粒子絮凝的二次絮凝结构的纤维素粉末。

公开(公告)号：US06699845B2

公开(公告)日：2004-03-02

申请号：US09759104

申请日：2001-01-12

申请人： Kazuhiro Oobae ,  Etsuo Kamada ,  Shun'ichi Gomi

发明人： Kazuhiro Oobae ,  Etsuo Kamada ,  Shun'ichi Gomi

IPC分类号： A61K317016

CPC分类号： A61K9/1623 ,  A61K47/26

摘要： An excipient comprising trehalose having a purity of 99.0% or more, a proportion of particles of 75 &mgr;m or more of 2 to 90 wt %, an average particle size of 10 to 250 &mgr;m, an apparent specific volume of 1.5 to 3.5 ml/g, and a whiteness of 90% or more.

摘要翻译： 包含纯度为99.0％以上的海藻糖，75μm以上2〜90wt％的颗粒的比例，10〜250μm的平均粒径，1.5〜3.5ml / g的表观比容量的赋形剂 ，白度为90％以上。