公开(公告)号：US08507485B2

公开(公告)日：2013-08-13

申请号：US12931072

申请日：2011-01-24

申请人： Hisashi Tajima ,  Takahiro Honda ,  Kenji Kawashima ,  Kazuyoshi Okamoto ,  Minoru Yamamoto

发明人： Hisashi Tajima ,  Takahiro Honda ,  Kenji Kawashima ,  Kazuyoshi Okamoto ,  Minoru Yamamoto

IPC分类号： A61K31/5377 ,  A61K31/506

CPC分类号： C07D401/14 ,  C07D239/42 ,  C07D401/12 ,  C07D409/12

摘要： A method of treating a disease associated with angiogenesis by administering a therapeutically effective amount of a compound represented by the formula (1) or a salt thereof wherein the ring X represents R1 and R2 independently represent a hydrogen atom, an alkyl, an aryl or an aromatic heterocyclic; R3 represents a hydrogen atom, a halogen atom, a hydroxy, an alkoxy, an aryloxy, an alkyl, an aryl, an amino, an alkylamino, a cycloalkylamino, an arylamino, an alkylcarbonylamino, an arylcarbonylamino, a mercapto, an alkylthio, an arylthio, an alkylsulfinyl or a nonaromatic heterocyclic; A1 represents a sulfur atom, a sulfinyl or a sulfonyl; and A2 represents an alkylene.

摘要翻译： 通过施用治疗有效量的由式（1）表示的化合物或其盐来治疗与血管生成相关的疾病的方法，其中环X表示R 1和R 2独立地表示氢原子，烷基，芳基或 芳香杂环; R 3表示氢原子，卤素原子，羟基，烷氧基，芳氧基，烷基，芳基，氨基，烷基氨基，环烷基氨基，芳基氨基，烷基羰基氨基，芳基羰基氨基，巯基，烷硫基 芳硫基，烷基亚磺酰基或非芳族杂环; A1表示硫原子，亚磺酰基或磺酰基; A2表示亚烷基。

公开(公告)号：US07739886B2

公开(公告)日：2010-06-22

申请号：US11915920

申请日：2006-05-31

申请人： Kazuyoshi Okamoto

发明人： Kazuyoshi Okamoto

IPC分类号： D04B7/04

CPC分类号： A41D1/04 ,  D04B1/106 ,  D04B1/246

摘要： A method of knitting a knitwear having an open part with a desired shape in which overlapping state of the open part is freely designed; the method comprising the steps of (a) to (f): a) a body is knitted by return knitting up to a joining starting location with a open part as a turn back position, wherein a right and left bodies are abutted at an overlapping portion of the open part, and a boundary of the front and back knitted is positioned on the needle bed on which the back body is assigned; b) rotating the body so that one of the boundaries is positioned between the front and back needle beds; c) joining the body and one of the left and right sleeve tubular parts (sleeve) to form one tubular part at one of the boundaries of the body and a joining side boundary of the sleeve; d) rotating the tubular part formed in step c so that the other boundary of the body is positioned between the front and back needle beds; e) joining the body and the other sleeve to form one tubular part at the other boundary of the body and a joining side boundary of the sleeve; and f) knitting the tubular part formed in step e by return knitting towards shoulder parts with the open part as a turn-back position.

摘要翻译： 一种编织具有开放部分的针织品的方法，所述开口部分具有自由设计所述开放部分的重叠状态的期望形状; 所述方法包括以下步骤：（a）至（f）：a）通过返回编织到主体的连接起始位置，以打开部分为转向位置，其中左右主体以重叠的方式邻接 开口部的一部分，前后针织物的边界位于分配有背部主体的针床上; b）使身体旋转，使得一个边界位于前针床和后针床之间; c）连接主体和左右套筒管件之一（套筒），以在主体的边界之一和套筒的接合边界处形成一个管状部件; d）旋转在步骤c中形成的管状部分，使得主体的另一边界位于前针床和后针床之间; e）连接主体和另一个套筒，以在主体的另一边界和套筒的接合侧边界处形成一个管状部件; 以及f）通过以打开部分作为折回位置的朝向肩部部分的退回编织来编织在步骤e中形成的管状部件。

公开(公告)号：US07529596B2

公开(公告)日：2009-05-05

申请号：US10585853

申请日：2005-01-12

申请人： Kazuyoshi Okamoto

发明人： Kazuyoshi Okamoto

IPC分类号： D04B7/30

CPC分类号： D04B1/243

摘要： A knitting method of knit pants knitted using a flat knitting machine, wherein the knitting starts at a side part on either right side or left side including a side part of a vertical rise part and a side part of a leg part and ends at a side part on the other leg side including a side part of a vertical rise part and a side part of a leg part. A front knitted fabric part and a back knitted fabric part are knitted in the following steps so that a length of the front knitted fabric part from the side to the crotch can be made shorter than a length of the back knitted fabric part from the side to the crotch. The steps comprises the first step of doing the knitting to set up to join and knit the side part of the vertical rise part and the side part of the leg part on the one leg side, the second step of knitting the vertical rise part and leg part of the front knitted fabric part on the one leg side and also knitting the vertical rise part and leg part of the back knitted fabric part on the one leg side, the third step of joining together and binding off inside leg joining parts of the leg parts on the one leg side, the forth step of doing the knitting to set up to join and knit the inside leg joining parts of the leg parts on the other leg side, the fifth step of knitting the vertical rise part and leg part of the front knitted fabric part on the other leg side and also knitting the vertical rise part and leg part of the back knitted fabric part on the other leg side, and the sixth step of joining together and binding off the side part of the vertical rise part and the side part of the leg part on the other leg side. This knitting method can provide the knit pants that fit more beautifully to one's figure and look more beautiful externally when wearing.

摘要翻译： 一种使用横机编织的编织裤的编织方法，其中，所述编织从包括竖直上升部分的侧部和腿部的侧部的右侧或左侧的侧部开始，并且在侧面 部分在另一个腿侧，包括垂直上升部分的侧部和腿部的侧部。 前针织物部分和后针织物部分按照以下步骤进行编织，使得从侧面到裆部的前针织物部分的长度可以比​​背面针织物部分的从侧面到 裆部。 这些步骤包括进行编织以在一个腿侧上连接并编织垂直上升部分的侧部和腿部的侧部的第一步骤，编织垂直上升部分和腿部的第二步骤 在一个腿侧的前针织部分的一部分，并且还在一个腿侧编织后针织物部分的垂直上升部分和腿部的第三步骤，将腿部接合部分的腿部接合在一起 在一条腿侧的部分，进行编织的第四步骤，将另一腿侧的腿部的内腿连接部分进行编织，第五步编织 在另一腿侧的前针织物部分，并且还编织另一腿侧的后针织物部分的垂直上升部分和腿部，以及第六步骤，将垂直上升部分的侧部和 腿的侧面部分 部分在另一边。 这种针织方法可以提供更美观的针织裤，穿着时外观更美观。

公开(公告)号：US07414909B2

公开(公告)日：2008-08-19

申请号：US11606025

申请日：2006-11-30

申请人： Kazuyoshi Okamoto ,  Kazumasa Yanagisawa

发明人： Kazuyoshi Okamoto ,  Kazumasa Yanagisawa

IPC分类号： G11C7/02

CPC分类号： G11C7/14 ,  G11C17/12

摘要： There is provided a high-density mask ROM operable at a high speed. With the mask ROM, respective source lines are disposed so as to be shared by memory cells in respective columns adjacent to each other, and bit lines are disposed so as to correspond to the respective columns of the memory cells. Further, the dummy cells are disposed for the respective columns of the memory cells. The dummy cells are each made up of a series-circuit including a first switching transistor that is turned into the conducting state in response to a signal potential on a dummy word line (DWL), and a second switching transistor 17 for coupling an adjacent source line to the bit line corresponding thereto in response to a potential of the source line in a column corresponding thereto. The memory cells each are made up of one unit of a transistor and a data storage formed by mask wiring. At the time of reading data, a potential of the source line in a select column is caused to undergo a change, whereupon there occurs a potential difference between a pair made up of the bit line as selected to which the memory cells as selected are coupled, and a reference bit line with the dummy cells coupled thereto, so that it is possible to execute readout of data by detecting the potential difference.

摘要翻译： 提供了可高速操作的高密度掩模ROM。 利用掩模ROM，各个源极线被布置成由彼此相邻的各个列中的存储单元共享，并且位线被布置为与存储单元的各个列对应。 此外，为存储单元的各列设置虚设单元。 虚拟单元各自由串联电路组成，串联电路包括响应于虚拟字线（DWL）上的信号电位而变为导通状态的第一开关晶体管，以及用于耦合相邻源极的第二开关晶体管17 响应于与其对应的列中的源极线的电位，对应于其的位线。 每个存储单元由晶体管的一个单元和由掩模布线形成的数据存储器构成。 在读取数据时，使选择列中的源极线的电位发生变化，由此选择由选择的存储器单元所耦合的位线组成的一对之间存在电位差 以及与其耦合的虚拟单元的参考位线，使得可以通过检测电位差来执行数据的读出。

公开(公告)号：US20080021064A1

公开(公告)日：2008-01-24

申请号：US11897308

申请日：2007-08-30

申请人： Kenji Kawashima ,  Takahiro Honda ,  Hisashi Tajima ,  Kazuyoshi Okamoto ,  Minoru Yamamoto

发明人： Kenji Kawashima ,  Takahiro Honda ,  Hisashi Tajima ,  Kazuyoshi Okamoto ,  Minoru Yamamoto

IPC分类号： A61K31/4709 ,  C07D401/02 ,  C07D409/02

CPC分类号： C07D215/12 ,  C07D215/20 ,  C07D401/12 ,  C07D401/14 ,  C07D409/12

摘要： The present invention relates to a synthesis study of novel cyclic compounds having a quinolylalkylthio group represented by the formula (1), and pharmacological actions of the compounds. In the formula, the ring X represents: which may have halogen and/or alkyl; R1 and R2 independently represent hydrogen, alkyl, cycloalkyl, aryl or a (non) aromatic heterocycle; R3 represents qinolyl; A represents sulfur, sulfinyl or sulfonyl; and B represents alkylene.

摘要翻译： 本发明涉及具有由式（1）表示的喹啉基烷硫基的新型环状化合物的合成研究以及该化合物的药理作用。 在该式中，环X表示：其可具有卤素和/或烷基; R 1和R 2独立地代表氢，烷基，环烷基，芳基或（非）芳族杂环; R 3表示喹啉基; A代表硫，亚磺酰基或磺酰基; B表示亚烷基。

公开(公告)号：US20070127302A1

公开(公告)日：2007-06-07

申请号：US11606025

申请日：2006-11-30

申请人： Kazuyoshi Okamoto ,  Kazumasa Yanagisawa

发明人： Kazuyoshi Okamoto ,  Kazumasa Yanagisawa

IPC分类号： G11C7/02

CPC分类号： G11C7/14 ,  G11C17/12

摘要： There is provided a high-density mask ROM operable at a high speed. With the mask ROM, respective source lines are disposed so as to be shared by memory cells in respective columns adjacent to each other, and bit lines are disposed so as to correspond to the respective columns of the memory cells. Further, the dummy cells are disposed for the respective columns of the memory cells. The dummy cells are each made up of a series-circuit including a first switching transistor that is turned into the conducting state in response to a signal potential on a dummy word line (DWL), and a second switching transistor 17 for coupling an adjacent source line to the bit line corresponding thereto in response to a potential of the source line in a column corresponding thereto. The memory cells each are made up of one unit of a transistor and a data storage formed by mask wiring. At the time of reading data, a potential of the source line in a select column is caused to undergo a change, whereupon there occurs a potential difference between a pair made up of the bit line as selected to which the memory cells as selected are coupled, and a reference bit line with the dummy cells coupled thereto, so that it is possible to execute readout of data by detecting the potential difference.

摘要翻译： 提供了可高速操作的高密度掩模ROM。 利用掩模ROM，各个源极线被布置成由彼此相邻的各个列中的存储单元共享，并且位线被布置为与存储单元的各个列对应。 此外，为存储单元的各列设置虚设单元。 虚拟单元各自由串联电路组成，串联电路包括响应于虚拟字线（DWL）上的信号电位而变为导通状态的第一开关晶体管，以及用于耦合相邻源极的第二开关晶体管17 响应于与其对应的列中的源极线的电位，对应于其的位线。 每个存储单元由晶体管的一个单元和由掩模布线形成的数据存储器构成。 在读取数据时，使选择列中的源极线的电位发生变化，由此选择由所选择的存储器单元耦合到的位线构成的一对之间存在电位差 以及与其耦合的虚拟单元的参考位线，使得可以通过检测电位差来执行数据的读出。

公开(公告)号：US20050229641A1

公开(公告)日：2005-10-20

申请号：US10525765

申请日：2003-08-25

申请人： Kazuyoshi Okamoto

发明人： Kazuyoshi Okamoto

IPC分类号： D04B1/24 ,  D04B7/04

CPC分类号： D04B1/24

摘要： A tubular knitted fabric (11) having a first knitted fabric and a second knitted fabric joined together continuously at both ends thereof and a laminating part (4) formed in the first knitted fabric at which the knitted fabric is partly laminated in two or more layers is knitted by the method comprising the step of forming the tubular knitted fabric via a full-gauge loop arrangement, the knitting width widening step (s3) of shifting loops of wale where the laminating part (4) is formed and loops of wale positioned closer to a side end of the knitted fabric than the wale where the laminating part (4) is formed, to provide a half-gauge loop arrangement wherein empty needles for stitch transfer are arranged between needles used for forming the loops of the wale where the laminating part (4) is formed, and the step (s4) of knitting the first knitted fabric and the second knitted fabric, while the loops of wale where the laminating part (4) is formed are formed to be fine in size so that when the knitting is ended, the loops of wale where the laminating part (4) is formed can be substantially equal in size to the loops in other region than the loops of wale where the laminating part (4) is formed. This can prevent texture differences between the respective knitted fabric parts including the laminating part (4) at which the knitting fabric is partly laminated in multilayer.

摘要翻译： 一种具有第一针织物和第二针织物的管状针织物（11），所述第一针织物和第二针织物在其两端连续地连接在一起，并且形成在第一针织物中的层压部分（4），其中针织物部分地层压成两层或更多层 通过包括通过全量规环路布置形成管状针织物的步骤的方法进行编织，形成层压部分（4）的纵行环形的编织宽度扩大步骤（s 3） 比形成有层压部件（4）的纵行更靠近针织物的侧端，以提供半规环路布置，其中用于缝合传送的空针布置在用于形成纵行环的针的针之间 形成层压部（4），并且形成第一针织物和第二针织物的步骤（s4），同时形成层压部（4）的纵行环形成为细 尺寸使得当针织结束时，形成层压部分（4）的纵行环可以与其中形成层压部分（4）的纵行环的其它区域中的环相比大致相等。 这可以防止包括层叠部分（4）在各个针织物部分之间的纹理差异，其中编织织物部分地层压在多层中。

公开(公告)号：US20050081568A1

公开(公告)日：2005-04-21

申请号：US10503809

申请日：2003-02-03

申请人： Kazuyoshi Okamoto

发明人： Kazuyoshi Okamoto

IPC分类号： D04B1/22 ,  D04B1/24 ,  D04B7/04

CPC分类号： D04B1/106 ,  D04B1/22 ,  D04B1/246 ,  D10B2501/061

摘要： In a method of knitting a tubular knitted fabric comprising a first knitted fabric and a second knitted fabric, regions A, B, C in the first knitted fabric of the tubular knitted fabric are folded back at their respective boundaries and then overlapped with a corresponding part of the second knitted fabric and held in that overlapped state. The method comprises (a) the step of forming the region A in the state in which the regions B and C of the first knitted fabric and the second knitted fabric are attached to needles on the second needle bed, (b) the step of forming the region B of the first knitted fabric in the state in which the region A of the first knitted fabric is attached to needles on the first needle bed and also the region C of the first knitted fabric and the second knitted fabric are attached to the needles on the second needle bed, (c) the step of forming the region C of the first knitted fabric in the state in which the regions A and B of the first knitted fabric is attached to the needles on the first needle bed and also the second knitted fabric is attached to the needles on the second needle bed, and (d) the step of forming the second knitted fabric in the state in which the regions A, B, and C of the first knitted fabric are attached to the needles on the first needle bed. This knitting can permit knitting of the tubular knitted fabric of a larger diameter using the needle bed having the common width.

公开(公告)号：US06857294B2

公开(公告)日：2005-02-22

申请号：US10478860

申请日：2002-05-23

申请人： Kazuyoshi Okamoto

发明人： Kazuyoshi Okamoto

IPC分类号： D04B1/10 ,  D04B1/24 ,  D04B7/26 ,  D04B7/04 ,  D04B15/66

CPC分类号： D04B1/126 ,  D04B1/24 ,  D04B7/26 ,  D10B2403/0333

摘要： An object of the invention is to obtain an intarsia pattern fabric which is not likely to cause yarn entanglement, eliminates the need for divided knitting, and provides good productivity even when a cylindrical knitting fabric is to be knitted. in a double bed flat knitting machine, a carriage and an intarsia carrier capable of knitting with two sets of cams are used to knit two courses of knitting fabric by moving a carriage six courses. An intarsia pattern is knitted at a front needle bed FB, and a knitting yarn between the intarsia carrier halted near a boundary and a knitting needle F is used to perform kick-back of the intarsia carrier by the third-course movement of the carriage. A back body is knitted while the yarn is hooked on an unused knitting needle F in a back needle bed BB. The sixth-course movement of the carriage releases a knitting yarn from the knitting beed F in the back needle bed BB while the back body is being knitted.

摘要翻译： 本发明的目的是获得不易引起纱线缠结的嵌花图案织物，不需要分割针织，并且即使在编织圆筒针织物时也能提供良好的生产率。 在双床平针织机中，可以使用两套凸轮进行编织的托架和嵌花架，通过移动滑架6个横列来编织两个针织布。 在前针床FB处编织嵌花图案，并且在边界附近停止的嵌花架和编织针F之间的针织纱线被用于通过托架的第三次移动来执行嵌花支架的反射。 当将纱线钩在后针床BB中的未使用的针织针F上时，编织后身。 马车的第六道路运动在后针床BB的针​​织针F中释放编织纱线，同时编织后身。

公开(公告)号：US06796149B2

公开(公告)日：2004-09-28

申请号：US10467922

申请日：2003-08-14

申请人： Kazuyoshi Okamoto ,  Yukihide Maeda

发明人： Kazuyoshi Okamoto ,  Yukihide Maeda

IPC分类号： D04B704

CPC分类号： D04B1/246

摘要： In a process of knitting a fabric during which at least a part of loops in the flechage knitting region are transferred between the front and back needle beds to move the loops laterally, loops in a stitch move region which are moved laterally whenever an adequate number of courses of the flechage knitting region are knitted are transferred to an opposite needle bed and then the front and back needle beds are moved relative to each other. Then, loops of wale which are put in the rest state in a process of the flechage knitting are held on the needle bed opposite to the needle bed on which loops of a next course are formed in a sequent flechage knitting until the stitch move is completed. Only the loops of the wale in which the loops of the next course are formed in the sequent knitting are transferred back to their originally retained needle bed prior to the forming of the loops of the next course. This knitting is repeatedly performed. This can allow the knitting of the region where the flechage knitting and the stitch move are performed concurrently without incurring problems such as stitch drop, yarn breakage, and the like.