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公开(公告)号：US4108725A
公开(公告)日：1978-08-22
申请号：US714202
申请日：1976-08-13
IPC分类号： C12P19/44 , A61K31/70 , A61K31/7028 , A61P31/04 , C07H15/04 , C12P1/04 , C12R1/38 , C12D9/20
CPC分类号： C07H15/04 , Y10S435/874
摘要： A novel aminoglycoside antibiotic complex designated herein as Bu-2183 is produced by fermentation of Pseudomonas sp. strain D946-B83, A.T.C.C. 31086. Complex Bu-2183 is known to consist of at least five components, said components being herein designated Bu-2183 A, A.sub.2, B, C and D. The complex and the individual aminoglycoside components Bu-2183 A, A.sub.2, and B are found to have a broad spectrum of antibacterial activity and are especially useful in inhibiting aminoglycoside-resistant organisms including Pseudomonas species.
摘要翻译： 本文命名为Bu-2183的新型氨基糖苷类抗生素复合物是通过发酵假单胞菌属（Pseudomonas sp。 菌株D946-B83，A.T.C.C. 已知复合物Bu-2183由至少五种组分组成，所述组分在本文中称为Bu-2183A，A2，B，C和D.复合物和单独的氨基糖苷组分Bu-2183A，A2和B 被发现具有广谱的抗菌活性，并且特别可用于抑制氨基糖苷类抗性生物体，包括假单胞菌属物种。
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公开(公告)号：US4012576A
公开(公告)日：1977-03-15
申请号：US627391
申请日：1975-10-30
IPC分类号： A61K31/70 , A61K31/7028 , A61P31/04 , C07H15/04 , C12P1/04 , C12P19/44 , A61K35/00 , C07H15/22
CPC分类号： C07H15/04 , Y10S435/874
摘要： A novel aminoglycoside antibiotic complex designated herein as Bu-2183 is produced by fermentation of Pseudomonas sp. strain D946-B83, A.T.C.C. 31086. Complex Bu-2183 is known to consist of at least five components, said components being herein designated Bu-2183 A, A.sub.2, B, C and D. The complex and the individual aminoglycoside components Bu-2183 A, A.sub.2, and B are found to have a broad spectrum of antibacterial activity and are especially useful in inhibiting aminoglycoside-resistant organisms including Pseudomonas species.
摘要翻译： 本文命名为Bu-2183的新型氨基糖苷类抗生素复合物是通过发酵假单胞菌属（Pseudomonas sp。 菌株D946-B83，A.T.C.C. 已知复合物Bu-2183由至少五种组分组成，所述组分在本文中称为Bu-2183A，A2，B，C和D.复合物和单独的氨基糖苷组分Bu-2183A，A2和B 被发现具有广谱的抗菌活性，并且特别可用于抑制氨基糖苷类抗性生物体，包括假单胞菌属物种。
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