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公开(公告)号:US20130012584A1
公开(公告)日:2013-01-10
申请号:US13620148
申请日:2012-09-14
IPC分类号: A61K31/195 , A61P15/00
CPC分类号: A61K9/2054 , A61K9/2009 , A61K9/2013 , A61K9/2027 , A61K9/2059 , A61K31/19 , A61K31/195 , A61K31/196 , Y10S514/951
摘要: Disclosed are modified release oral tranexamic acid formulations and methods of treatment therewith.
摘要翻译: 本发明公开了口服氨甲环酸制剂及其治疗方法。
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公开(公告)号:US08298304B1
公开(公告)日:2012-10-30
申请号:US12378950
申请日:2009-02-20
申请人: Keith A. Moore
发明人: Keith A. Moore
IPC分类号: C10L9/00
CPC分类号: C10L9/08 , F23K1/00 , F23K1/04 , F23K3/02 , F23K2201/1006 , F23K2201/30 , F23K2900/01001
摘要: A coal treatment process containing a coal-beneficiation process module. The module is implemented into the conventional coal treatment process of a coal-fired power plant after a first step of grinding the coal in a coal mill. The process module sequentially extracts chemical substances of non-combustible ash, water, mercury and oil that are found in coal before the coal is fired, so that present invention can produce valuable products and achieve a high quality cleaned powdered coal-char to burn in a furnace to thereby reduce pollution and increase the efficiency of energy production from the coal.
摘要翻译: 包含选煤过程模块的煤处理过程。 在煤磨机研磨第一步之后,该模块被实施到燃煤电厂的常规煤处理过程中。 工艺模块依次提取燃煤之前在煤中发现的不燃灰,水,汞,油等化学物质,使本发明能够生产有价值的产品,实现高质量清洁的粉煤炭燃烧 从而减少污染,提高煤炭能源生产效率。
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公开(公告)号:US08110606B2
公开(公告)日:2012-02-07
申请号:US12706117
申请日:2010-02-16
申请人: Mark M. Kowalski , James L. Young , Keith A. Moore
发明人: Mark M. Kowalski , James L. Young , Keith A. Moore
IPC分类号: A61K31/195
CPC分类号: A61K31/196 , A61K9/4825 , A61K9/4858 , A61K9/4866
摘要: A method is provided for treating pain in patients recovering from post-surgical trauma by administering between about 13 to about 30 mg of diclofenac potassium in a liquid dispersible formulation over a period of at least 24 hours, wherein the daily total amount of diclofenac potassium administered is less than or equal to about 100 mg. The method is particularly useful in treating acute pain in bunionectomy patients.
摘要翻译: 提供了一种通过在至少24小时内施用约13至约30mg液体可分散制剂中的双氯芬酸钾的方法来治疗从手术后创伤中恢复的患者的疼痛的方法,其中施用双氯芬酸钾的日总量 小于或等于约100mg。 该方法特别适用于治疗单纯切除术患者的急性疼痛。
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公开(公告)号:US20100143468A1
公开(公告)日:2010-06-10
申请号:US12714181
申请日:2010-02-26
IPC分类号: A61K9/26 , A61K31/195 , A61P7/04
CPC分类号: A61K9/0053 , A61K9/2009 , A61K9/2013 , A61K9/2027 , A61K9/2054 , A61K9/2059 , A61K9/2846 , A61K9/2866 , A61K31/195 , A61K31/196
摘要: Disclosed are modified release oral tranexamic acid formulations and methods of treatment therewith.
摘要翻译: 本发明公开了口服氨甲环酸制剂及其治疗方法。
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公开(公告)号:US08957113B2
公开(公告)日:2015-02-17
申请号:US13016800
申请日:2011-01-28
IPC分类号: A61K31/19 , A61K31/195 , A61K9/20 , A61K9/28
CPC分类号: A61K31/195 , A61K9/2009 , A61K9/2027 , A61K9/2054 , A61K9/2059 , A61K9/2846 , A61K9/2866
摘要: Disclosed are immediate release oral tranexamic acid formulations and methods of treatment therewith.
摘要翻译: 公开了立即释放的口服氨甲环酸制剂及其治疗方法。
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公开(公告)号:US08022106B2
公开(公告)日:2011-09-20
申请号:US12433510
申请日:2009-04-30
IPC分类号: A61K31/19 , A61K31/195
CPC分类号: A61K31/195 , A61K9/2027 , A61K9/2054 , A61K9/2077
摘要: Disclosed are modified release oral tranexamic acid formulations and methods of treatment therewith.
摘要翻译: 本发明公开了口服氨甲环酸制剂及其治疗方法。
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公开(公告)号:US20090214644A1
公开(公告)日:2009-08-27
申请号:US12433247
申请日:2009-04-30
IPC分类号: A61K31/195 , A61K9/22 , A61P43/00
CPC分类号: A61K9/2027 , A61K9/1676 , A61K9/2054 , A61K9/2846 , A61K9/2866 , A61K31/195
摘要: Disclosed are delayed release oral tranexamic acid formulations and methods of treatment therewith.
摘要翻译: 公开了延迟释放的口服氨甲环酸制剂及其治疗方法。
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公开(公告)号:US20090209646A1
公开(公告)日:2009-08-20
申请号:US12433510
申请日:2009-04-30
IPC分类号: A61K31/195 , A61P1/08
CPC分类号: A61K31/195 , A61K9/2027 , A61K9/2054 , A61K9/2077
摘要: Disclosed are modified release oral tranexamic acid formulations and methods of treatment therewith.
摘要翻译: 本发明公开了口服氨甲环酸制剂及其治疗方法。
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公开(公告)号:US20090017114A1
公开(公告)日:2009-01-15
申请号:US12283694
申请日:2008-09-15
CPC分类号: A61K9/2054 , A61K9/2027 , A61K31/195
摘要: Tranexamic acid formulated in an oral dosage form with at least one agent that decreases tranexamic acid release in the stomach. Such formulations minimize nausea, vomiting, and other adverse gastric effects that may accompany tranexamic acid therapy, for example, to treat heavy menstrual bleeding. One embodiment is an extended release formulation with waxes, polymers, etc. that prevent a bolus release of tranexamic acid in the stomach. An alternative embodiment is a delayed release formulation with polymers that prevent release of tranexamic acid in the acid environment of the stomach and delay its release until the formulation reaches the less acid environment of the intestines. Such formulations enhance patient compliance with therapy because adverse effects of tranexamic acid therapy are reduced.
摘要翻译: 以口服剂型配制的氨甲环酸与至少一种降低胃中氨甲环酸释放的试剂。 这样的制剂可以减少恶心,呕吐和其他可能伴随凝血酸治疗的不良胃部作用,例如治疗重度月经出血。 一个实施方案是具有蜡,聚合物等的延长释放制剂,其防止胃中释放氨甲环酸。 替代实施方案是具有聚合物的延迟释放制剂,其防止胃酸的酸性环境中的氨甲环酸的释放并延迟其释放直到制剂达到肠的较少的酸性环境。 这种制剂增强了患者对治疗的依从性,因为降低了氨甲环酸治疗的不良反应。
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公开(公告)号:US09060939B2
公开(公告)日:2015-06-23
申请号:US13230902
申请日:2011-09-13
IPC分类号: A61K31/195 , A61K9/20 , A61K9/28
CPC分类号: A61K9/0053 , A61K9/2009 , A61K9/2013 , A61K9/2027 , A61K9/2054 , A61K9/2059 , A61K9/2846 , A61K9/2866 , A61K31/195 , A61K31/196
摘要: Disclosed are modified release oral tranexamic acid formulations and methods of treatment therewith.
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