公开(公告)号：US20130052636A1

公开(公告)日：2013-02-28

申请号：US13590915

申请日：2012-08-21

申请人： Ravi Kant Verma ,  Kenneth Mathew Zangwill ,  Ashraf Samir Ibrahim

发明人： Ravi Kant Verma ,  Kenneth Mathew Zangwill ,  Ashraf Samir Ibrahim

IPC分类号： G01N21/65 ,  C12M1/42

CPC分类号： C12M41/46 ,  G01N21/658

摘要： Some aspects of the invention provide for a method for detecting metabolic activity in a sample by obtaining a sample, illuminating the sample at a plurality of time points, measuring transmitted light from a marker of metabolic activity in the sample at the plurality of time points, and detecting the presence or absence of metabolic activity from a change in the transmitted light at the plurality of time points. Other aspects of the invention provide for a method for detecting metabolic activity in a sample by providing a sample have a detectable marker therein that is reflective of metabolic activity in the sample, producing an amplified signal from the marker, measuring the amplified signal at a plurality of time points, and detecting metabolic activity from a change in the signal. Additional aspects provide for a system for detecting metabolic activity in a sample.

摘要翻译： 本发明的一些方面提供了一种用于通过获得样品来检测样品中的代谢活性的方法，在多个时间点照射样品，测量来自多个时间点的样品中代谢活性的标志物的透射光， 并且从多个时间点的透射光的变化来检测是否存在代谢活动。 本发明的其它方面提供了一种通过提供样品中具有可检测标记物来检测样品中的代谢活性的方法，所述检测标记反映了样品中的代谢活性，从标记产生放大信号，测量多个放大信号 的时间点，并从信号的变化中检测代谢活动。 另外的方面提供用于检测样品中代谢活性的系统。