Microspectrometer based on a tunable fabry-perot interferometer and microsphere cavities
    1.
    发明授权
    Microspectrometer based on a tunable fabry-perot interferometer and microsphere cavities 失效
    基于可调谐的fabry-perot干涉仪和微球腔的显微光谱仪

    公开(公告)号:US06747742B1

    公开(公告)日:2004-06-08

    申请号:US10179724

    申请日:2002-06-24

    申请人: Ravi Kant Verma

    发明人: Ravi Kant Verma

    IPC分类号: G01B902

    摘要: The present invention is a cost-effective and compact micro-spectrometer for rapid detection of chemical compounds in the low concentration limit. The invention provides for significantly higher sensitivity compared to conventional spectroscopy techniques (continuous wave and Fourier transform methods) by placing the sample within a high Finesse etalon cavity. An Optical Spectrum Analyzer (OSA) built on either continuous wave (CW-SPEC), or Fourier Transform Absorption Spectroscopy (FT-SPEC) is used to monitor the spectrum from the etalon cavity/sample combination during tuning of the etalon cavity˜this information is then used to reconstruct the absorption spectrum.

    摘要翻译: 本发明是用于在低浓度限度下快速检测化合物的成本有效且紧凑的微光谱仪。 通过将样品放置在高Finesse标准具腔内,本发明提供了与常规光谱技术(连续波和傅里叶变换方法)相比显着更高的灵敏度。 使用连续波(CW-SPEC)或傅立叶变换吸收光谱(FT-SPEC)建立的光谱分析仪(OSA)来监测标准具腔/样品组合在标准光腔调谐期间的光谱〜该信息 然后用于重建吸收光谱。

    RAPID DETECTION OF METABOLIC ACTIVITY
    3.
    发明申请
    RAPID DETECTION OF METABOLIC ACTIVITY 审中-公开
    快速检测代谢活性

    公开(公告)号:US20130052636A1

    公开(公告)日:2013-02-28

    申请号:US13590915

    申请日:2012-08-21

    IPC分类号: G01N21/65 C12M1/42

    CPC分类号: C12M41/46 G01N21/658

    摘要: Some aspects of the invention provide for a method for detecting metabolic activity in a sample by obtaining a sample, illuminating the sample at a plurality of time points, measuring transmitted light from a marker of metabolic activity in the sample at the plurality of time points, and detecting the presence or absence of metabolic activity from a change in the transmitted light at the plurality of time points. Other aspects of the invention provide for a method for detecting metabolic activity in a sample by providing a sample have a detectable marker therein that is reflective of metabolic activity in the sample, producing an amplified signal from the marker, measuring the amplified signal at a plurality of time points, and detecting metabolic activity from a change in the signal. Additional aspects provide for a system for detecting metabolic activity in a sample.

    摘要翻译: 本发明的一些方面提供了一种用于通过获得样品来检测样品中的代谢活性的方法,在多个时间点照射样品,测量来自多个时间点的样品中代谢活性的标志物的透射光, 并且从多个时间点的透射光的变化来检测是否存在代谢活动。 本发明的其它方面提供了一种通过提供样品中具有可检测标记物来检测样品中的代谢活性的方法,所述检测标记反映了样品中的代谢活性,从标记产生放大信号,测量多个放大信号 的时间点,并从信号的变化中检测代谢活动。 另外的方面提供用于检测样品中代谢活性的系统。