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公开(公告)号:US08417465B2
公开(公告)日:2013-04-09
申请号:US12726140
申请日:2010-03-17
IPC分类号: G01N33/48
CPC分类号: G01N33/5082 , G01N33/5029 , G01N33/5032 , G01N33/54366 , G01N33/56972
摘要: An apparatus and method for assaying blood-brain barrier properties for drug and drug delivery vehicle screening comprising of a microfluidic apparatus with gaps separating lumen and tissue space enabling formation of tight junctions similar to in vivo conditions using endothelial cells and brain cells.
摘要翻译: 用于测定用于药物和药物递送载体筛选的血脑屏障性质的装置和方法,包括具有分隔内腔和组织空间的间隙的微流体装置,从而能够形成类似于使用内皮细胞和脑细胞的体内条件的紧密连接。