公开(公告)号：US09642935B1

公开(公告)日：2017-05-09

申请号：US13752326

申请日：2013-01-28

申请人： Robert L. Bundy ,  Kevin P. Armstrong

发明人： Robert L. Bundy ,  Kevin P. Armstrong

IPC分类号： A61L27/22 ,  A61L27/38 ,  A61L27/58

CPC分类号： A61L27/227 ,  A61L27/3821 ,  A61L27/3834 ,  A61L27/46 ,  A61L27/54 ,  A61L27/56 ,  A61L27/58 ,  A61L2300/414 ,  A61L2300/62 ,  A61L2430/02 ,  C08L5/08 ,  C08L89/06

摘要： There is disclosed a synthetic, composite graft to support robust bone growth. In an embodiment, the synthetic, composite graft includes a synthetic scaffold material including a material resorbable through natural cellular processes; a signaling factor combined with the scaffold material; a cell adherence factor coated on the scaffold material; a quantity of viable bone forming cells adhered to the scaffold; and a matrix substrate binding the scaffold material. There is disclosed a method of forming a synthetic, composite graft to support bone growth for bone grafting. In one embodiment, the method includes providing a synthetic scaffold material including a material resorbable through natural cellular processes; combining a signaling factor with the scaffold material; coating a cell adherence factor on the scaffold material; adhering a quantity of viable bone forming cells to the scaffold; and encasing the scaffold material with a matrix substrate. Other embodiments are also disclosed.