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1.发明申请MULTI COMPOSITION STICK PRODUCT AND A PROCESS AND SYSTEM FOR MANUFACTURING SAME 审中-公开多组分胶粘剂产品及其制造方法和系统公开(公告)号：US20060188315A1
公开(公告)日：2006-08-24
申请号：US11381843
申请日：2006-05-05
申请人： Jee Look , Paul Cooper , Khawla Abu-Izza , Joyce Wilson , Krishna Raman , Vincent Li
发明人： Jee Look , Paul Cooper , Khawla Abu-Izza , Joyce Wilson , Krishna Raman , Vincent Li
IPC分类号： A45D40/04
CPC分类号： A61K8/02 , A45D40/04 , A45D40/16 , A45D40/24 , A45D2040/0012 , A61K8/0229 , A61K8/31 , A61K8/35 , A61K8/37 , A61K8/44 , A61K8/553 , A61K8/92 , A61K8/922 , A61K8/927 , A61K2800/88 , A61Q1/06 , A61Q15/00 , A61Q17/04 , A61Q19/00 , B29C39/023 , B29C39/10 , B29C39/24 , B65B2220/14 , B65D83/00
摘要： A multi-composition stick product, such as a lip balm, sun screen, deodorant, or glue stick. The multi-composition stick product including a stick composition molded in the container so as to contact the walls thereof and be advanceable or ejected therefrom. The stick composition includes a first composition and a second composition. The first and second compositions differ in at least one component, such as a medicament, colorant, fragrance, flavorant, sunscreen, preservative, conditioner, moisturizer, emollient, or surfactant. Furthermore the first and second compositions are arranged in a predetermined non-random pattern that is reproducible. Also described is the method and apparatus for manufacturing the multi-composition stick product.
摘要翻译： 多组合棒产品，如唇膏，防晒霜，除臭剂或胶棒。 该多组合棒产品包括在该容器中成型以便与其壁接触并可前进或从其中弹出的棒状组合物。 棒组合物包括第一组合物和第二组合物。 第一和第二组合物在至少一种组分如药物，着色剂，香料，调味剂，防晒剂，防腐剂，调理剂，保湿剂，软化剂或表面活性剂中不同。 此外，第一和第二组合物以可再现的预定非随机图案排列。 还描述了用于制造多组合棒产品的方法和装置。
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2.发明申请公开(公告)号：US20050169858A1
公开(公告)日：2005-08-04
申请号：US11068128
申请日：2005-02-28
申请人： Jee Look , Paul Cooper , Khawla Abu-Izza , Joyce Wilson , Krishna Raman , Vincent Li
发明人： Jee Look , Paul Cooper , Khawla Abu-Izza , Joyce Wilson , Krishna Raman , Vincent Li
IPC分类号： A45D40/04 , A45D40/16 , A45D40/24 , A61K8/02 , A61K8/31 , A61K8/35 , A61K8/37 , A61K8/44 , A61K8/55 , A61K8/92 , A61Q1/06 , A61Q15/00 , A61Q17/04 , A61Q19/00 , B29C39/02 , B29C39/10 , B29C39/24 , B65D83/00 , A61K7/42
CPC分类号： A61K8/02 , A45D40/04 , A45D40/16 , A45D40/24 , A45D2040/0012 , A61K8/0229 , A61K8/31 , A61K8/35 , A61K8/37 , A61K8/44 , A61K8/553 , A61K8/92 , A61K8/922 , A61K8/927 , A61K2800/88 , A61Q1/06 , A61Q15/00 , A61Q17/04 , A61Q19/00 , B29C39/023 , B29C39/10 , B29C39/24 , B65B2220/14 , B65D83/00
摘要： A multi-composition stick product, such as a lip balm, sun screen, deodorant, or glue stick. The multi-composition stick product including a stick composition molded in the container so as to contact the walls thereof and be advanceable or ejected therefrom. The stick composition includes a first composition and a second composition. The first and second compositions differ in at least one component, such as a medicament, colorant, fragrance, flavorant, sunscreen, preservative, conditioner, moisturizer, emollient, or surfactant. Furthermore the first and second compositions are arranged in a predetermined non-random pattern that is reproducible. Also described is the method and apparatus for manufacturing the multi-composition stick product.
摘要翻译： 多组合棒产品，如唇膏，防晒霜，除臭剂或胶棒。 该多组合棒产品包括在该容器中成型以便与其壁接触并可前进或从其中弹出的棒状组合物。 棒组合物包括第一组合物和第二组合物。 第一和第二组合物在至少一种组分如药物，着色剂，香料，调味剂，防晒剂，防腐剂，调理剂，保湿剂，软化剂或表面活性剂中不同。 此外，第一和第二组合物以可再现的预定非随机图案排列。 还描述了用于制造多组合棒产品的方法和装置。
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公开(公告)号：US08877746B2
公开(公告)日：2014-11-04
申请号：US13391440
申请日：2010-08-24
IPC分类号： A61K31/55 , A61K31/355 , A01N43/62 , A01N43/16 , A61K47/22 , A61K31/5517
CPC分类号： A61K47/22 , A61K31/5517
摘要： Compositions and methods of making the same for in vivo delivery of lixivaptan to a subject in need thereof are described. The composition includes a substantially water-insoluble pharmacologically active agent (e.g., lixivaptan) and a substantially water-insoluble matrix forming material (e.g., a Vitamin E semi-ester), wherein the pharmacologically active agent is dispersed in said matrix forming material, and wherein the composition delivers said substantially water-insoluble pharmacologically active agent upon exposure to physiological medium.
摘要翻译： 描述了将其用于体内递送泻药至有此需要的受试者的组合物和方法。 该组合物包括基本上不溶于水的药理学活性剂（例如，酏剂）和基本上不溶于水的基质形成材料（例如维生素E半酯），其中药理活性剂分散在所述基质形成材料中，和 其中所述组合物在暴露于生理介质时递送所述基本上不溶于水的药理活性剂。
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公开(公告)号：US20130079334A1
公开(公告)日：2013-03-28
申请号：US13391440
申请日：2010-08-24
IPC分类号： A61K47/22 , A61K31/5517
CPC分类号： A61K47/22 , A61K31/5517
摘要： Compositions and methods of making the same for in vivo delivery of lixivaptan to a subject in need thereof are described. The composition includes a substantially water-insoluble pharmacologically active agent (e.g., lixivaptan) and a substantially water-insoluble matrix forming material (e.g., a Vitamin E semi-ester), wherein the pharmacologically active agent is dispersed in said matrix forming material, and wherein the composition delivers said substantially water-insoluble pharmacologically active agent upon exposure to physiological medium.
摘要翻译： 描述了将其用于体内递送泻药至有此需要的受试者的组合物和方法。 该组合物包括基本上不溶于水的药理学活性剂（例如，酏剂）和基本上不溶于水的基质形成材料（例如维生素E半酯），其中药理活性剂分散在所述基质形成材料中，和 其中所述组合物在暴露于生理介质时递送所述基本上不溶于水的药理活性剂。
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公开(公告)号：US20080038359A1
公开(公告)日：2008-02-14
申请号：US11874393
申请日：2007-10-18
申请人： Khawla ABU-IZZA
发明人： Khawla ABU-IZZA
IPC分类号： A61K9/14
CPC分类号： A61K9/145 , A61K9/10 , A61K9/5123 , A61K9/5192
摘要： The invention relates to pharmaceutically stable nanoparticle formulations of poorly soluble drug substances, to the processes for the preparation of such formulations, and to methods of use thereof.
摘要翻译： 本发明涉及药物稳定的难溶性药物物质的制剂，制备这些制剂的方法及其使用方法。
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公开(公告)号：US20080021103A1
公开(公告)日：2008-01-24
申请号：US11903458
申请日：2007-09-21
IPC分类号： A61K47/30 , A61K31/165 , A61K31/192 , A61K31/24
CPC分类号： A61K9/006 , A61K9/7015 , A61K47/32
摘要： The invention is directed to a topical medicament-containing composition which exhibits excellent bioadhesive properties suitable for application to the human body, including to mucous membranes.
摘要翻译： 本发明涉及一种局部含药组合物，其表现出优异的生物粘附性能，其适用于人体，包括粘膜。
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