公开(公告)号：US07547724B2

公开(公告)日：2009-06-16

申请号：US11606883

申请日：2006-12-01

申请人： Alain Laurent ,  Kim E. Hewitt ,  Stephen Morris ,  Patrick Bureau ,  Alain Boudreault ,  Scott Jarvis ,  James Jaquith

发明人： Alain Laurent ,  Kim E. Hewitt ,  Stephen Morris ,  Patrick Bureau ,  Alain Boudreault ,  Scott Jarvis ,  James Jaquith

IPC分类号： A61K31/427 ,  C07D417/04

CPC分类号： C07D207/16 ,  A61K38/00 ,  C07D403/06 ,  C07D403/14 ,  C07K5/0806

摘要： Disclosed is an isomer, enantiomer, diastereoisomer or tautomer of a compound represented by Formula I: or a salt thereof, in which R1, R2, R100, R200, A, A1, B, B1, BG, n, Q and Q1 are substituents described. Also disclosed is the use of compounds of Formula 1 to treat proliferative disorders.