公开(公告)号：US20060191844A1

公开(公告)日：2006-08-31

申请号：US10559398

申请日：2004-08-26

申请人： Kimihiro Mahuchi ,  Noriyuki Tamamura ,  Hidehiko Sakurai ,  Noriko Monden ,  Shinya Koyama ,  Hiroshi Shibano ,  Katsuaki Kuze ,  Katsuhiko Nose

发明人： Kimihiro Mahuchi ,  Noriyuki Tamamura ,  Hidehiko Sakurai ,  Noriko Monden ,  Shinya Koyama ,  Hiroshi Shibano ,  Katsuaki Kuze ,  Katsuhiko Nose

IPC分类号： B01D69/08

CPC分类号： B01D69/08 ,  A61M1/16 ,  B01D67/0083 ,  B01D67/0088 ,  B01D69/02 ,  B01D69/087 ,  B01D71/44 ,  B01D71/68 ,  B01D2323/02 ,  B01D2323/08 ,  B01D2323/12 ,  B01D2323/30 ,  B01D2325/02 ,  B01D2325/04 ,  B01D2325/20 ,  B01D2325/24

摘要： The present invention provides a highly water permeable hollow fiber membrane type blood purifier for medical use, which is excellent in safety and module-assembling ease and which has a high water permeability suitable for use in therapy of chronic renal failure. The present invention relates to a highly water-permeable hollow fiber type blood purifier comprising hydrophobic polymer hollow fiber membranes each of which contains a hydrophilic polymer, characterized in that the amount of the hydrophilic polymer eluted from the hollow fiber membrane is 10 ppm or less; in that the ratio of the hydrophilic polymer in the outer surface of the hollow fiber membrane is 25 to 50 mass %; in that the burst pressure of the hollow fiber membrane is 0.5 MPa or higher; and in that the coefficient of water permeability of the blood purifier is 150 ml/m2/hr./mmHg or higher.

摘要翻译： 本发明提供一种用于医疗用途的高水溶性中空纤维膜式血液净化器，其安全性和组装方便性优异，并且具有适用于慢性肾功能衰竭治疗的高透水性。 本发明涉及含有亲水性聚合物的疏水性聚合物中空纤维膜的高透水性中空纤维型血液净化剂，其特征在于，从中空纤维膜洗出的亲水性聚合物的量为10ppm以下， 因为中空丝膜的外表面的亲水性聚合物的比例为25〜50质量％。 中空纤维膜的爆破压力为0.5MPa以上; 血液净化器的透水系数为150ml / m 2 / hr./mmHg以上。