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公开(公告)号：US20100240891A1
公开(公告)日：2010-09-23
申请号：US12679599
申请日：2007-09-28
IPC分类号： C07D413/12 , C07C65/40 , C07D261/12 , C07D261/20
CPC分类号： C07D261/20 , A61K31/423
摘要： Pharmaceutical agents characterized by containing benzophenone derivatives represented by the general formula: wherein the each substituent is as defined in the specification, or salts thereof have suppressive effect on RANKL production, suppressive effect on OPG reduction and inhibitory effects on differentiation/activation of osteoclasts, and are extremely useful for treating, for example therapy and/or prevention, of various diseases in which differentiation/activation of osteoclast are involved, such as osteoporosis.
摘要翻译： 其特征在于含有以下通式表示的二苯甲酮衍生物：其中各取代基如说明书中所定义，或其盐对RANKL产生具有抑制作用，对OPG降低的抑制作用以及对破骨细胞分化/活化的抑制作用，以及 对于治疗和/或预防涉及破骨细胞分化/活化的各种疾病如骨质疏松症是非常有用的。
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公开(公告)号：US09012482B2
公开(公告)日：2015-04-21
申请号：US13287375
申请日：2011-11-02
IPC分类号： A61K31/423 , A61P19/10 , C07D261/20
CPC分类号： C07D261/20 , A61K31/423
摘要： Pharmaceutical agents characterized by containing benzophenone derivatives represented by the general formula: wherein the each substituent is as defined in the specification, or salts thereof have suppressive effect on RANKL production, suppressive effect on OPG reduction and inhibitory effects on differentiation/activation of osteoclasts, and are extremely useful for treating, for example therapy and/or prevention, of various diseases in which differentiation/activation of osteoclast are involved, such as osteoporosis.
摘要翻译： 其特征在于含有以下通式表示的二苯甲酮衍生物：其中各取代基如说明书中所定义，或其盐对RANKL产生具有抑制作用，对OPG降低的抑制作用以及对破骨细胞分化/活化的抑制作用，以及 对于治疗和/或预防涉及破骨细胞分化/活化的各种疾病如骨质疏松症是非常有用的。
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公开(公告)号：US20120046326A1
公开(公告)日：2012-02-23
申请号：US13287375
申请日：2011-11-02
IPC分类号： A61K31/423 , A61P19/10
CPC分类号： C07D261/20 , A61K31/423
摘要： Pharmaceutical agents characterized by containing benzophenone derivatives represented by the general formula: wherein the each substituent is as defined in the specification, or salts thereof have suppressive effect on RANKL production, suppressive effect on OPG reduction and inhibitory effects on differentiation/activation of osteoclasts, and are extremely useful for treating, for example therapy and/or prevention, of various diseases in which differentiation/activation of osteoclast are involved, such as osteoporosis.
摘要翻译： 其特征在于含有以下通式表示的二苯甲酮衍生物：其中各取代基如说明书中所定义，或其盐对RANKL产生具有抑制作用，对OPG降低的抑制作用以及对破骨细胞分化/活化的抑制作用，以及 对于治疗和/或预防涉及破骨细胞分化/活化的各种疾病如骨质疏松症是非常有用的。
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