公开(公告)号：US4695467A

公开(公告)日：1987-09-22

申请号：US751866

申请日：1985-07-05

Applicant: Toshinobu Uemura ,  Kiyohide Shinooka ,  Tokuaki Kajiho

Inventor： Toshinobu Uemura ,  Kiyohide Shinooka ,  Tokuaki Kajiho

IPC: A61K9/20 ,  A61K9/22 ,  A61K9/16

CPC classification number: A61K9/2095 ,  A61K9/2013 ,  A61K9/2054 ,  Y10S514/96

Abstract: The invention relates to a sustained release tablet which comprises easily disintegrable granules containing(a) a drug,(b) a disintegrating agent selected from the group consisting of starch derivatives, gums, cellulose derivatives and ion-exchange resins, and(c) a water soluble polymer selected from the group consisting of cellulose derivatives, synthetic water soluble polymers and polysaccharides, the surfaces of which granules are treated solely with a wax selected from the group consisting of plant or animal wax, hydrogenated oils and paraffin.

Abstract translation: 本发明涉及一种缓释片剂，其包含容易崩解的颗粒，其含有（a）药物，（b）选自淀粉衍生物，树胶，纤维素衍生物和离子交换树脂的崩解剂，和（c） 选自纤维素衍生物，合成水溶性聚合物和多糖的水溶性聚合物，其表面仅用选自植物或动物蜡，氢化油和石蜡的蜡进行处理。

公开(公告)号：US4690822A

公开(公告)日：1987-09-01

申请号：US839077

申请日：1986-03-12

Applicant: Toshinobu Uemura ,  Toshiaki Okhuma ,  Kiyohide Shinooka ,  Hiroshi Ishikuro ,  Yoshio Ueda

Inventor： Toshinobu Uemura ,  Toshiaki Okhuma ,  Kiyohide Shinooka ,  Hiroshi Ishikuro ,  Yoshio Ueda

IPC: A61K47/14 ,  A61K9/48 ,  A61K9/50 ,  A61K9/66 ,  A61K47/00 ,  A61K47/30 ,  A61K47/38 ,  A61K9/52

CPC classification number: A61K9/5078 ,  A61K9/4858 ,  A61K9/4866

Abstract: The invention relates to a pharmaceutical oral capsule preparation filled with a substantially anhydrous mixture which is in solid or semi-solid form comprising:(a) a drug or a drug treated by a conventional manner, each of which is in solid form, and(b) a drug carrier which is a semi-solid mixture comprising a selected aqueous polymer and a selected liquid oil, the ratio of aqueous polymer to liquid oil by weight being 2:1 to 1:40.

Abstract translation: 本发明涉及一种填充有固体或半固体形式的基本上无水的混合物的药物口服胶囊制剂，其包含：（a）以常规方式治疗的药物或药物，每种药物或药物均为固体形式，和（ b）药物载体，其是包含选定的水性聚合物和选择的液体油的半固体混合物，水性聚合物与液体油的重量比为2:1至1:40。