-
公开(公告)号:US20100092947A1
公开(公告)日:2010-04-15
申请号:US11921996
申请日:2006-06-07
申请人: Laurent Essioux , Dorothee Foernzler , Lara Hashimoto , Klaus Lindpaintner , Michelle Rashford , Olivia Spleiss , Matt Truman , Athina Voulgari
发明人: Laurent Essioux , Dorothee Foernzler , Lara Hashimoto , Klaus Lindpaintner , Michelle Rashford , Olivia Spleiss , Matt Truman , Athina Voulgari
IPC分类号: C12Q1/68
CPC分类号: C12Q1/6883 , C12Q2600/106 , C12Q2600/156 , C12Q2600/158
摘要: The present invention concerns a method for the prediction of acute renal transplant rejection by detecting a polymorphism in intron 7 of the IMPDH2 gene, optionally in combination with polymorphisms of the MDR1 and IL 10 genes which were found to be associated with this disease.
摘要翻译: 本发明涉及通过检测IMPDH2基因的内含子7的多态性来预测急性肾移植排斥的方法,任选地与发现与该疾病相关的MDR1和IL10基因的多态性组合。
-
公开(公告)号:US20090286235A1
公开(公告)日:2009-11-19
申请号:US11921998
申请日:2006-06-07
申请人: Laurent Essioux , Dorothee Foernzler , Lara Hashimoto , Klaus Lindpaintner , Michelle Rashford , Olivia Spleiss , Matt Truman , Athina Voulgari
发明人: Laurent Essioux , Dorothee Foernzler , Lara Hashimoto , Klaus Lindpaintner , Michelle Rashford , Olivia Spleiss , Matt Truman , Athina Voulgari
IPC分类号: C12Q1/68
CPC分类号: C12Q1/6883 , C12Q2600/106 , C12Q2600/156
摘要: The present invention concerns a method for the prediction of acute renal transplant rejection by detecting a polymorphism in exon 26 of the MDR1 gene, optionally in combination with polymorphisms of the IMPDH2 and IL 10 genes which were found to be associated with this disease.
摘要翻译: 本发明涉及一种通过检测MDR1基因的外显子26多态性来预测急性肾移植排斥的方法,任选地与被发现与该疾病相关的IMPDH2和IL10基因的多态性组合。
-
公开(公告)号:US20090286234A1
公开(公告)日:2009-11-19
申请号:US11921997
申请日:2006-06-07
申请人: Laurent Essioux , Dorothee Foernzler , Lara Hashimoto , Klaus Lindpaintner , Michelle Rashford , Olivia Spleiss , Matt Truman , Athina Voulgari
发明人: Laurent Essioux , Dorothee Foernzler , Lara Hashimoto , Klaus Lindpaintner , Michelle Rashford , Olivia Spleiss , Matt Truman , Athina Voulgari
IPC分类号: C12Q1/68
CPC分类号: C12Q1/6883 , C12Q2600/106 , C12Q2600/156
摘要: The present invention concerns a method for the prediction of acute renal transplant rejection by detecting a poly-morphism in the promoter region of the IL 10 gene, optionally in combination with polymorphisms of the MDR1 and IMPDH2 genes which were found to be associated with this disease.
摘要翻译: 本发明涉及通过检测IL 10基因的启动子区域中的多态性来预测急性肾移植排斥的方法,任选地与发现与该疾病相关的MDR1和IMPDH2基因的多态性组合 。
-
-