公开(公告)号：US5779765A

公开(公告)日：1998-07-14

申请号：US679255

申请日：1996-07-12

申请人： Konrad Grob ,  Fausto Munari

发明人： Konrad Grob ,  Fausto Munari

IPC分类号： G01N30/02 ,  G01N30/12 ,  B01D15/08

CPC分类号： G01N30/12 ,  G01N2030/025 ,  G01N2030/126

摘要： To inject a liquid sample with large volume into a GC column of a gas chromatograph, its volatile portion is evaporated by heat, in a non-selective way, in a vaporization chamber, the vapors thus generated being fed to pre-column located upstream of the GC column and maintained at a lower temperature to that of the vaporization chamber, where such compounds are separated from the solvent vapors, which are unloaded into the atmosphere while the compounds to be analyzed are sent to the GC column.

摘要翻译： 为了将大量体积的液体样品注入气相色谱仪的GC色谱柱，其挥发性部分以非选择性的方式在蒸发室中被热量蒸发，由此产生的蒸气被送入位于 气相色谱柱并保持在比蒸发室更低的温度，其中这些化合物与溶剂蒸气分离，溶剂蒸气被卸载到大气中，同时待分析的化合物被送到气相色谱柱。

公开(公告)号：US06779379B2

公开(公告)日：2004-08-24

申请号：US09898505

申请日：2001-07-03

申请人： Konrad Grob ,  Fausto Munari ,  Paolo Magni

发明人： Konrad Grob ,  Fausto Munari ,  Paolo Magni

IPC分类号： G01N100

CPC分类号： G01N30/12 ,  G01N2030/127

摘要： The invention concerns a device for vaporizing injections of samples into a gas chromatography analysis device, comprising a vaporization chamber elongated lengthways and heated, as well as a syringe equipped with a needle, the device being of the type in which the introduction of the sample is carried out without prior vaporization of the sample within the needle, and also foresees at least one stop and vaporization means for the liquid inside the vaporization chamber. To improve the conditions of vaporization and the transfer of the sample, the distance between the free end of the needle and the stated stop and vaporization means for the liquid is greater than 55 mm (FIG. 1).

摘要翻译： 本发明涉及用于将样品注入气相色谱分析装置中的装置，其包括纵向延伸并加热的蒸发室以及装有针的注射器，该装置是将样品引入的类型 在针内没有样品的先前蒸发的情况下进行，并且还预示了用于蒸发室内的液体的至少一个停止和蒸发装置。 为了改善蒸发和样品转移的条件，针的自由端与所述液体的停止和蒸发装置之间的距离大于55mm（图1）。

公开(公告)号：US06451614B1

公开(公告)日：2002-09-17

申请号：US09588400

申请日：2000-06-06

申请人： Konrad Grob ,  Fausto Munari ,  Sorin Trestianu ,  Paolo Magni

发明人： Konrad Grob ,  Fausto Munari ,  Sorin Trestianu ,  Paolo Magni

IPC分类号： G01N3002

CPC分类号： G01N30/18 ,  G01N30/12 ,  G01N2030/126 ,  Y10T436/2575 ,  G01N2030/8447

摘要： A method and device for vaporization injection in which there is at least one constriction between the end of the sample injection needle or tube and the interior of the heated vaporization chamber. The terminal part of the needle or tube can be heated to improve nebulisation of the sample and therefore its vaporization speed.

摘要翻译： 一种用于汽化喷射的方法和装置，其中在样品注射针或管的端部与加热的蒸发室的内部之间存在至少一个收缩。 可以加热针或管的末端部分以改善样品的雾化并因此改善其蒸发速度。

公开(公告)号：US5347844A

公开(公告)日：1994-09-20

申请号：US004086

申请日：1993-01-13

申请人： Konrad Grob ,  Fausto Munari

发明人： Konrad Grob ,  Fausto Munari

IPC分类号： G01N30/12

CPC分类号： G01N30/12 ,  G01N2030/127

摘要： The invention concerns a process and a device for splitless vaporizing injection of samples into equipments of gas chromatographic analysis.The technique is applied specially when liquid samples generate volumes of vapors which cannot be housed inside the vaporizing chamber.Inside the vaporisation chamber, kept at high temperature, evaporation of the sample solvent forms a cool zone where the solutes are retained while the solvent vapors expand out of the vaporizing chamber and leave the injector. The sample liquid is kept in place within the vaporization chamber by suitable obstacles or by a packing material. At the end of solvent evaporation, i.e. when cooling ceases, the injection zone returns to the regulated injector temperature and the compounds to be analysed are transferred to the column by the carrier gas.

摘要翻译： 本发明涉及一种用于将样品分离注入气相色谱分析设备的方法和装置。 当液体样品产生体积不能容纳在蒸发室内的蒸气时，该技术被特别应用。 在蒸发室内，保持在高温下，样品溶剂的蒸发形成一个冷却区，其中溶剂被保留，同时溶剂蒸气膨胀出蒸发室并离开喷射器。 样品液体通过适当的障碍物或包装材料保持在蒸发室内的适当位置。 在溶剂蒸发结束时，即冷却停止时，注入区返回到调节的注射器温度，待分析的化合物被载气转移到塔中。

公开(公告)号：US06638346B1

公开(公告)日：2003-10-28

申请号：US10110482

申请日：2002-07-11

申请人： Paolo Magni ,  Fausto Munari ,  Konrad Grob

发明人： Paolo Magni ,  Fausto Munari ,  Konrad Grob

IPC分类号： B01D1508

CPC分类号： G01N30/12 ,  G01N2030/127

摘要： A vaporization injector for gas chromatography analysis instruments, of the type including a vaporization chamber, heated or which may be heated, with a longitudinally elongated shape, a device for hermetically inserting the needle of a syringe containing the sample (substance to be analysed and solvent) into the chamber, a connection for feeding a carrier gas into the chamber and a gas chromatography capillary column with an upstream end open inside the vaporization chamber. In order to allow the vaporization of large sample volumes, the upstream end of the gas-chromatography column and the injection point of the sample into the vaporization chamber are both arranged adjacent to one of the longitudinal ends of the vaporization chamber and the feed connection for the carrier gas is located adjacent to the other end.

摘要翻译： 一种用于气相色谱分析仪器的蒸发注射器，其包括被加热或可被加热的具有纵向细长形状的蒸发室，用于气密地插入含有样品（待分析物质和溶剂的物质）的针头的装置 ）到室中，用于将载气进料到室中的连接和气化色谱毛细管柱，其上游端在蒸发室内部打开。 为了允许大的样品体积的蒸发，气相色谱柱的上游端和样品进入蒸发室的注入点都被布置成与蒸发室的纵向端之一相邻，并且进料连接用于 载气位于另一端附近。

公开(公告)号：US06257047B1

公开(公告)日：2001-07-10

申请号：US09315697

申请日：1999-05-20

申请人： Konrad Grob ,  Fausto Munari ,  Pier Albino Colombo ,  Paolo Magni

发明人： Konrad Grob ,  Fausto Munari ,  Pier Albino Colombo ,  Paolo Magni

IPC分类号： B01D1508

CPC分类号： G01N30/16 ,  G01N2030/127 ,  G01N2030/167

摘要： The invention concerns a method and an apparatus for the direct injection of large volumes (>3 &mgr;l) of samples into the column in a gas chromatography analysis apparatus comprising an oven, a gas chromatography column lodged in the oven, a means for the direct transfer into the column of the sample and a source of carrier gas upstream the column, as well as a detector downstream the column. According to the invention two or more of the parameters: nature of the solvent injection rate flow-rate and/or pressure of the carrier gas temperature at least of an initial length of the column during the injection are correlated and/or controlled to achieve a control of the length of the zone wetted by the sample during its introduction.

摘要翻译： 本发明涉及一种用于在气相色谱分析设备中直接将大量（> 3mL）样品直接注入柱中的方法和装置，该装置包括烘箱，置于烘箱中的气相色谱柱，用于直接转印的装置 进入样品柱和柱上游的载气源，以及柱下游的检测器。根据本发明，两个或多个参数：载体的注入速率流速和/或压力的性质 至少在注入期间柱的初始长度的温度相关和/或被控制以实现样品在其引入期间润湿的区域的长度的控制。

公开(公告)号：US5759234A

公开(公告)日：1998-06-02

申请号：US768960

申请日：1996-12-18

申请人： Fausto Munari ,  Pier Albino Colombo ,  Konrad Grob

发明人： Fausto Munari ,  Pier Albino Colombo ,  Konrad Grob

IPC分类号： G01N30/12 ,  G01N30/16 ,  B01D15/08

CPC分类号： G01N30/12 ,  G01N2030/127 ,  G01N2030/167

摘要： The invention relates to a method and a device to control the physical conditions of the solvent within a pre-column, in a gas chromatography analysis apparatus. To achieve desired and controlled conditions of recondensation in the pre-column with vaporization injectors or of vaporation with "on-column" injectors, the dew-point of the solvent in the pre-column is calculated and the factors which influence this dew-point are varied and/or the temperature of the pre-column is varied, in order to set such temperatures in a desired correlation.

摘要翻译： 本发明涉及在气相色谱分析装置中控制预柱中溶剂物理条件的方法和装置。 为了通过蒸发注射器或蒸发式“柱内”注射器在预柱中实现所需和受控的再凝结条件，计算预柱中溶剂的露点和影响该露点的因素 变化和/或改变预柱的温度，以便将所述温度设置在期望的相关性中。

公开(公告)号：US06389879B1

公开(公告)日：2002-05-21

申请号：US09260226

申请日：1999-03-01

申请人： Konrad Grob ,  Fausto Munari ,  Pier Albino Colombo

发明人： Konrad Grob ,  Fausto Munari ,  Pier Albino Colombo

IPC分类号： G01N3018

CPC分类号： G01N30/12 ,  G01N2030/025 ,  G01N2030/127 ,  G01N2030/8804

摘要： This invention concerns a method, a device, and an apparatus to detect changes of state in a capillary tube, in particular a gas-chromatographic column or pre-column and to consequently control the conditions under which samples are injected or introduced. The detection is carried out through changes in the temperature of the capillary tube, and/or changes in pressure, or flow rate of the carrier gas. The invention further concerns a method to control gas-chromatography functions by means of a specially designed software, based on the above-mentioned detections on a sample apparatus.

摘要翻译： 本发明涉及一种用于检测毛细管，特别是气相色谱柱或预柱中的状态变化的方法，装置和装置，并因此控制注入或引入样品的条件。 通过毛细管的温度变化和/或载气的压力或流速的变化进行检测。本发明还涉及通过专门设计的软件控制气相色谱分析功能的方法， 基于上述对样品装置的检测。

公开(公告)号：US5174149A

公开(公告)日：1992-12-29

申请号：US704366

申请日：1991-05-23

申请人： Konrad Grob ,  Fausto Munari

发明人： Konrad Grob ,  Fausto Munari

IPC分类号： G01N1/00 ,  G01N30/10 ,  G01N30/12 ,  G01N30/30 ,  G01N30/40

CPC分类号： G01N30/12 ,  G01N1/22 ,  G01N2030/3046 ,  G01N30/10 ,  G01N30/40

摘要： The present invention relates to devices and processes for the introduction of a liquid sample into an apparatus for gas chromatographic analysis. A sample is injected into a vaporization chamber positioned upstream of a gas chromatographic column. The vaporization chamber is equipped with a means to feed a carrier gas selectively into the chamber, the chamber being kept at a temperature at least equal to the boiling temperature of the solvent at the operating pressure. A separation is effectuated between the sample and its carrier solvent, the solvent vapor is exhausted through an exhaust duct. Thereafter, the flow of carrier gas is restored to the chamber and the separated solvent is exhausted from the chamber through a separate outline into a gas chromatographic column.