公开(公告)号：US06779379B2

公开(公告)日：2004-08-24

申请号：US09898505

申请日：2001-07-03

申请人： Konrad Grob ,  Fausto Munari ,  Paolo Magni

发明人： Konrad Grob ,  Fausto Munari ,  Paolo Magni

IPC分类号： G01N100

CPC分类号： G01N30/12 ,  G01N2030/127

摘要： The invention concerns a device for vaporizing injections of samples into a gas chromatography analysis device, comprising a vaporization chamber elongated lengthways and heated, as well as a syringe equipped with a needle, the device being of the type in which the introduction of the sample is carried out without prior vaporization of the sample within the needle, and also foresees at least one stop and vaporization means for the liquid inside the vaporization chamber. To improve the conditions of vaporization and the transfer of the sample, the distance between the free end of the needle and the stated stop and vaporization means for the liquid is greater than 55 mm (FIG. 1).

摘要翻译： 本发明涉及用于将样品注入气相色谱分析装置中的装置，其包括纵向延伸并加热的蒸发室以及装有针的注射器，该装置是将样品引入的类型 在针内没有样品的先前蒸发的情况下进行，并且还预示了用于蒸发室内的液体的至少一个停止和蒸发装置。 为了改善蒸发和样品转移的条件，针的自由端与所述液体的停止和蒸发装置之间的距离大于55mm（图1）。

公开(公告)号：US06451614B1

公开(公告)日：2002-09-17

申请号：US09588400

申请日：2000-06-06

申请人： Konrad Grob ,  Fausto Munari ,  Sorin Trestianu ,  Paolo Magni

发明人： Konrad Grob ,  Fausto Munari ,  Sorin Trestianu ,  Paolo Magni

IPC分类号： G01N3002

CPC分类号： G01N30/18 ,  G01N30/12 ,  G01N2030/126 ,  Y10T436/2575 ,  G01N2030/8447

摘要： A method and device for vaporization injection in which there is at least one constriction between the end of the sample injection needle or tube and the interior of the heated vaporization chamber. The terminal part of the needle or tube can be heated to improve nebulisation of the sample and therefore its vaporization speed.

摘要翻译： 一种用于汽化喷射的方法和装置，其中在样品注射针或管的端部与加热的蒸发室的内部之间存在至少一个收缩。 可以加热针或管的末端部分以改善样品的雾化并因此改善其蒸发速度。

公开(公告)号：US06638346B1

公开(公告)日：2003-10-28

申请号：US10110482

申请日：2002-07-11

申请人： Paolo Magni ,  Fausto Munari ,  Konrad Grob

发明人： Paolo Magni ,  Fausto Munari ,  Konrad Grob

IPC分类号： B01D1508

CPC分类号： G01N30/12 ,  G01N2030/127

摘要： A vaporization injector for gas chromatography analysis instruments, of the type including a vaporization chamber, heated or which may be heated, with a longitudinally elongated shape, a device for hermetically inserting the needle of a syringe containing the sample (substance to be analysed and solvent) into the chamber, a connection for feeding a carrier gas into the chamber and a gas chromatography capillary column with an upstream end open inside the vaporization chamber. In order to allow the vaporization of large sample volumes, the upstream end of the gas-chromatography column and the injection point of the sample into the vaporization chamber are both arranged adjacent to one of the longitudinal ends of the vaporization chamber and the feed connection for the carrier gas is located adjacent to the other end.

摘要翻译： 一种用于气相色谱分析仪器的蒸发注射器，其包括被加热或可被加热的具有纵向细长形状的蒸发室，用于气密地插入含有样品（待分析物质和溶剂的物质）的针头的装置 ）到室中，用于将载气进料到室中的连接和气化色谱毛细管柱，其上游端在蒸发室内部打开。 为了允许大的样品体积的蒸发，气相色谱柱的上游端和样品进入蒸发室的注入点都被布置成与蒸发室的纵向端之一相邻，并且进料连接用于 载气位于另一端附近。

公开(公告)号：US06257047B1

公开(公告)日：2001-07-10

申请号：US09315697

申请日：1999-05-20

申请人： Konrad Grob ,  Fausto Munari ,  Pier Albino Colombo ,  Paolo Magni

发明人： Konrad Grob ,  Fausto Munari ,  Pier Albino Colombo ,  Paolo Magni

IPC分类号： B01D1508

CPC分类号： G01N30/16 ,  G01N2030/127 ,  G01N2030/167

摘要： The invention concerns a method and an apparatus for the direct injection of large volumes (>3 &mgr;l) of samples into the column in a gas chromatography analysis apparatus comprising an oven, a gas chromatography column lodged in the oven, a means for the direct transfer into the column of the sample and a source of carrier gas upstream the column, as well as a detector downstream the column. According to the invention two or more of the parameters: nature of the solvent injection rate flow-rate and/or pressure of the carrier gas temperature at least of an initial length of the column during the injection are correlated and/or controlled to achieve a control of the length of the zone wetted by the sample during its introduction.

摘要翻译： 本发明涉及一种用于在气相色谱分析设备中直接将大量（> 3mL）样品直接注入柱中的方法和装置，该装置包括烘箱，置于烘箱中的气相色谱柱，用于直接转印的装置 进入样品柱和柱上游的载气源，以及柱下游的检测器。根据本发明，两个或多个参数：载体的注入速率流速和/或压力的性质 至少在注入期间柱的初始长度的温度相关和/或被控制以实现样品在其引入期间润湿的区域的长度的控制。

公开(公告)号：US06579345B2

公开(公告)日：2003-06-17

申请号：US09868555

申请日：2001-12-10

申请人： Fausto Munari ,  Giancinto Zillioli ,  Roberto Raffaeta ,  Riccardo Facchetti ,  Paolo Magni

发明人： Fausto Munari ,  Giancinto Zillioli ,  Roberto Raffaeta ,  Riccardo Facchetti ,  Paolo Magni

IPC分类号： B01D1508

CPC分类号： G05D23/1912 ,  G01N30/30 ,  G01N2030/3061

摘要： A method and an apparatus for chromatography are described, wherein at least one element in electrically conductive material is provided to heat the capillary column in a direct way and wherein the control of the temperature is carried out according to a mathematical model having a component of predictive type, or Feed Forward type, that describes the thermodynamic behavior of the assembly comprising the electrically conductive element and the column at least as a function of the thermal resistance and the thermal capacity of the assembly thus constituted in order to regulate the supply of electrical power supplied to the conductive element.

公开(公告)号：US06389879B1

公开(公告)日：2002-05-21

申请号：US09260226

申请日：1999-03-01

申请人： Konrad Grob ,  Fausto Munari ,  Pier Albino Colombo

发明人： Konrad Grob ,  Fausto Munari ,  Pier Albino Colombo

IPC分类号： G01N3018

CPC分类号： G01N30/12 ,  G01N2030/025 ,  G01N2030/127 ,  G01N2030/8804

摘要： This invention concerns a method, a device, and an apparatus to detect changes of state in a capillary tube, in particular a gas-chromatographic column or pre-column and to consequently control the conditions under which samples are injected or introduced. The detection is carried out through changes in the temperature of the capillary tube, and/or changes in pressure, or flow rate of the carrier gas. The invention further concerns a method to control gas-chromatography functions by means of a specially designed software, based on the above-mentioned detections on a sample apparatus.

摘要翻译： 本发明涉及一种用于检测毛细管，特别是气相色谱柱或预柱中的状态变化的方法，装置和装置，并因此控制注入或引入样品的条件。 通过毛细管的温度变化和/或载气的压力或流速的变化进行检测。本发明还涉及通过专门设计的软件控制气相色谱分析功能的方法， 基于上述对样品装置的检测。

公开(公告)号：US5347844A

公开(公告)日：1994-09-20

申请号：US004086

申请日：1993-01-13

申请人： Konrad Grob ,  Fausto Munari

发明人： Konrad Grob ,  Fausto Munari

IPC分类号： G01N30/12

CPC分类号： G01N30/12 ,  G01N2030/127

摘要： The invention concerns a process and a device for splitless vaporizing injection of samples into equipments of gas chromatographic analysis.The technique is applied specially when liquid samples generate volumes of vapors which cannot be housed inside the vaporizing chamber.Inside the vaporisation chamber, kept at high temperature, evaporation of the sample solvent forms a cool zone where the solutes are retained while the solvent vapors expand out of the vaporizing chamber and leave the injector. The sample liquid is kept in place within the vaporization chamber by suitable obstacles or by a packing material. At the end of solvent evaporation, i.e. when cooling ceases, the injection zone returns to the regulated injector temperature and the compounds to be analysed are transferred to the column by the carrier gas.

摘要翻译： 本发明涉及一种用于将样品分离注入气相色谱分析设备的方法和装置。 当液体样品产生体积不能容纳在蒸发室内的蒸气时，该技术被特别应用。 在蒸发室内，保持在高温下，样品溶剂的蒸发形成一个冷却区，其中溶剂被保留，同时溶剂蒸气膨胀出蒸发室并离开喷射器。 样品液体通过适当的障碍物或包装材料保持在蒸发室内的适当位置。 在溶剂蒸发结束时，即冷却停止时，注入区返回到调节的注射器温度，待分析的化合物被载气转移到塔中。

公开(公告)号：US07818994B2

公开(公告)日：2010-10-26

申请号：US11596194

申请日：2005-05-11

申请人： Fausto Munari ,  Paolo Magni ,  Koni Grob

发明人： Fausto Munari ,  Paolo Magni ,  Koni Grob

IPC分类号： G01N1/00 ,  G01N30/12

CPC分类号： G01N30/12 ,  G01N2030/127 ,  G01N2030/165 ,  G01N30/34 ,  G01N30/16 ,  G01N2030/126

摘要： The present invention relates to a method for injecting a sample (i.e. a material to be analyzed that may be dissolved in a solvent) in a vaporization chamber or in a pre-column or a gas chromatograper, this method implying separately injecting a co-solvent, with the co-solvent being injected in advance of the sample and/or in a point in the vaporization chamber other than the sample injection point.

摘要翻译： 本发明涉及一种用于在蒸发室或预柱或气相色谱仪中注入样品（即待分析物质可溶于溶剂的方法），该方法意味着分别注入共溶剂 ，其中共溶剂在样品之前和/或在除了样品注入点之外的蒸发室中的点中注入。

公开(公告)号：US20080257013A1

公开(公告)日：2008-10-23

申请号：US11596194

申请日：2005-05-11

申请人： Fausto Munari ,  Paolo Magni ,  Koni Grob

发明人： Fausto Munari ,  Paolo Magni ,  Koni Grob

IPC分类号： G01N1/00

CPC分类号： G01N30/12 ,  G01N2030/127 ,  G01N2030/165 ,  G01N30/34 ,  G01N30/16 ,  G01N2030/126

摘要： The present invention relates to a method for injecting a sample (i.e. a material to be analyzed that may be dissolved in a solvent) in a vaporization chamber or in a pre-column or a gas chromatograper, this method implying separately injecting a co-solvent, with the co-solvent being injected in advance of the sample and/or in a point in the vaporization chamber other than the sample injection point.

摘要翻译： 本发明涉及一种用于在蒸发室或预柱或气相色谱仪中注入样品（即待分析物质可溶于溶剂的方法），该方法意味着分别注入共溶剂 ，其中共溶剂在样品之前和/或在除了样品注入点之外的蒸发室中的点中注入。

公开(公告)号：US5859360A

公开(公告)日：1999-01-12

申请号：US646308

申请日：1996-05-15

申请人： Paolo Magni ,  Giacinto Zilioli ,  Fausto Munari ,  Sorin Trestianu ,  Pieralbino Colombo

发明人： Paolo Magni ,  Giacinto Zilioli ,  Fausto Munari ,  Sorin Trestianu ,  Pieralbino Colombo

IPC分类号： G01N30/02 ,  G01N30/30 ,  G01N30/32 ,  G01N30/86 ,  C07C1/135

CPC分类号： G01N30/32 ,  G01N2030/025 ,  G01N2030/3084 ,  G01N2030/324 ,  G01N30/8658

摘要： There is provided a method and apparatus for controlling the carrier gas flow through a gas chromatographic apparatus with capillary column subjected to variations in temperature, through control of feeding pressure achieved following computerized processing of the equation of the carrier flow rate as a function of inlet pressure, column temperature and system structural parameters, including preliminary determination of the system parameters through detection of pressure, temperature and flow rate values in stabilized conditions of carrier passage through apparatus and calculation of a constant representing said parameters on the basis of values detected and in application of the aforesaid equation; storage of aforesaid constant; utilization of constant in the mentioned equation for controlling carrier flow rate through calculation and control of its feeding pressure during utilization of the gas chromatographic apparatus.

摘要翻译： PCT No.PCT / EP95 / 03627 Sec。 371日期：1996年5月15日 102（e）日期1996年5月15日PCT提交1995年9月15日PCT公布。 公开号WO96 / 08718 日期1996年3月21日提供了一种方法和装置，用于控制通过气相色谱仪的载气流动，毛细管柱经受温度变化，通过控制通过计算机处理载体流速方程式后的进料压力， 入口压力，柱温度和系统结构参数的函数，包括通过检测载体通过设备的稳定条件下的压力，温度和流量值初步确定系统参数，并计算基于 检测到的值和上述方程的应用; 储存上述常数; 利用上述方程中的常数，通过计算和控制气相色谱仪利用期间的进料压力来控制载流子流量。