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公开(公告)号:US20140308201A1
公开(公告)日:2014-10-16
申请号:US14204023
申请日:2014-03-11
Applicant: David Bryant BATT , Seth Alexander Ettenberg , Nicole Haubst , Tiancen Hu , David Jenkins , Engin Toksoz , Konstantin Petropoulos , Matthew John Meyer
Inventor: David Bryant BATT , Seth Alexander Ettenberg , Nicole Haubst , Tiancen Hu , David Jenkins , Engin Toksoz , Konstantin Petropoulos , Matthew John Meyer
CPC classification number: C07K16/2863 , A61K31/496 , A61K31/5025 , A61K31/506 , A61K31/662 , A61K45/06 , A61K47/48384 , A61K47/48561 , A61K47/6803 , A61K47/6849 , A61K2039/505 , C07K2317/565 , C07K2317/732 , C07K2317/92 , A61K2300/00
Abstract: The present invention relates to anti-FGFR2 antibodies, antibody fragments, antibody drug conjugates, and their uses for the treatment of cancer.
Abstract translation: 本发明涉及抗FGFR2抗体,抗体片段,抗体药物偶联物及其用于治疗癌症的用途。
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公开(公告)号:US10538587B2
公开(公告)日:2020-01-21
申请号:US14853003
申请日:2015-09-14
Applicant: Joelle Deplazes-Lauber , Christy Fryer , Tiacen Hu , David Jenkins , Konstantin Petropoulos , Philippe Thiel
Inventor: Joelle Deplazes-Lauber , Christy Fryer , Tiacen Hu , David Jenkins , Konstantin Petropoulos , Philippe Thiel
IPC: C07K16/28 , A61K39/395 , G01N33/574 , C07K14/705 , C07K14/71 , A61K39/00
Abstract: The present disclosure relates to antibodies or fragments thereof that target at least one conformational epitope of a Notch 3 or mutant Notch 3 receptor; and compositions and methods of use thereof.
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公开(公告)号:US20180009889A1
公开(公告)日:2018-01-11
申请号:US14853003
申请日:2015-09-14
Applicant: Joelle DEPLAZES-LAUBER , Christy FRYER , Tiacen HU , David JENKINS , Konstantin PETROPOULOS , Philippe THIEL
Inventor: Joelle DEPLAZES-LAUBER , Christy FRYER , Tiacen HU , David JENKINS , Konstantin PETROPOULOS , Philippe THIEL
IPC: C07K16/28 , G01N33/574
Abstract: The present disclosure relates to antibodies or fragments thereof that target at least one conformational epitope of a Notch 3 or mutant Notch 3 receptor; and compositions and methods of use thereof.
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公开(公告)号:US20170106095A1
公开(公告)日:2017-04-20
申请号:US15291024
申请日:2016-10-11
Applicant: David Bryant BATT , Seth Alexander Ettenberg , Nicole Haubst , Tiancen Hu , David Jenkins , Engin Toksoz , Konstantin Petropoulos , Matthew John Meyer
Inventor: David Bryant BATT , Seth Alexander Ettenberg , Nicole Haubst , Tiancen Hu , David Jenkins , Engin Toksoz , Konstantin Petropoulos , Matthew John Meyer
IPC: A61K39/00 , C07K16/30 , A61K31/506 , C07K16/28 , A61K45/06
CPC classification number: C07K16/30 , A61K31/506 , A61K45/06 , A61K47/549 , A61K47/6803 , A61K47/6849 , A61K47/6879 , A61K2039/505 , C07K16/2863 , C07K16/3015 , C07K16/3023 , C07K16/303 , C07K16/3038 , C07K16/3046 , C07K16/3069 , C07K2317/21 , C07K2317/31 , C07K2317/33 , C07K2317/34 , C07K2317/52 , C07K2317/55 , C07K2317/565 , C07K2317/73 , C07K2317/732 , C07K2317/75 , C07K2317/76 , C07K2317/92 , C07K2319/00
Abstract: The present invention relates to anti-FGFR2 and FGFR4 antibodies, antibody fragments, antibody drug conjugates, and their uses for the treatment of cancer.
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公开(公告)号:US20170008964A1
公开(公告)日:2017-01-12
申请号:US15204210
申请日:2016-07-07
Applicant: David Bryant Batt , Seth Alexander Ettenberg , Nicole Haubst , Tiancen HU , David Jenkins , Matthew John Meyer , Konstantin Petropoulos , Engin Toksoz
Inventor: David Bryant Batt , Seth Alexander Ettenberg , Nicole Haubst , Tiancen HU , David Jenkins , Matthew John Meyer , Konstantin Petropoulos , Engin Toksoz
IPC: C07K16/28 , A61K31/506 , A61K47/48
CPC classification number: C07K16/2863 , A61K31/496 , A61K31/5025 , A61K31/506 , A61K31/662 , A61K45/06 , A61K47/6803 , A61K47/6849 , A61K2039/505 , C07K2317/565 , C07K2317/732 , C07K2317/92 , A61K2300/00
Abstract: The present invention relates to anti-FGFR2 antibodies, antibody fragments, antibody drug conjugates, and their uses for the treatment of cancer.
Abstract translation: 本发明涉及抗FGFR2抗体,抗体片段,抗体药物偶联物及其用于治疗癌症的用途。
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公开(公告)号:US09498532B2
公开(公告)日:2016-11-22
申请号:US14203997
申请日:2014-03-11
Applicant: David Bryant Batt , Seth Alexander Ettenberg , Nicole Haubst , Tiancen Hu , David Jenkins , Engin Toksoz , Konstantin Petropoulos , Matthew John Meyer
Inventor: David Bryant Batt , Seth Alexander Ettenberg , Nicole Haubst , Tiancen Hu , David Jenkins , Engin Toksoz , Konstantin Petropoulos , Matthew John Meyer
CPC classification number: C07K16/30 , A61K31/506 , A61K45/06 , A61K47/549 , A61K47/6803 , A61K47/6849 , A61K47/6879 , A61K2039/505 , C07K16/2863 , C07K16/3015 , C07K16/3023 , C07K16/303 , C07K16/3038 , C07K16/3046 , C07K16/3069 , C07K2317/21 , C07K2317/31 , C07K2317/33 , C07K2317/34 , C07K2317/52 , C07K2317/55 , C07K2317/565 , C07K2317/73 , C07K2317/732 , C07K2317/75 , C07K2317/76 , C07K2317/92 , C07K2319/00
Abstract: The present invention relates to anti-FGFR2 and FGFR4 antibodies, antibody fragments, antibody drug conjugates, and their uses for the treatment of cancer.
Abstract translation: 本发明涉及抗FGFR2和FGFR4抗体,抗体片段,抗体药物偶联物及其用于治疗癌症的用途。
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公开(公告)号:US20140301946A1
公开(公告)日:2014-10-09
申请号:US14203997
申请日:2014-03-11
Applicant: David Bryant BATT , Seth Alexander Ettenberg , Nicole Haubst , Tiancen Hu , David Jenkins , Engin Toksoz , Konstantin Petropoulos , Matthew John Meyer
Inventor: David Bryant BATT , Seth Alexander Ettenberg , Nicole Haubst , Tiancen Hu , David Jenkins , Engin Toksoz , Konstantin Petropoulos , Matthew John Meyer
CPC classification number: C07K16/30 , A61K31/506 , A61K45/06 , A61K47/549 , A61K47/6803 , A61K47/6849 , A61K47/6879 , A61K2039/505 , C07K16/2863 , C07K16/3015 , C07K16/3023 , C07K16/303 , C07K16/3038 , C07K16/3046 , C07K16/3069 , C07K2317/21 , C07K2317/31 , C07K2317/33 , C07K2317/34 , C07K2317/52 , C07K2317/55 , C07K2317/565 , C07K2317/73 , C07K2317/732 , C07K2317/75 , C07K2317/76 , C07K2317/92 , C07K2319/00
Abstract: The present invention relates to anti-FGFR2 and FGFR4 antibodies, antibody fragments, antibody drug conjugates, and their uses for the treatment of cancer.
Abstract translation: 本发明涉及抗FGFR2和FGFR4抗体,抗体片段,抗体药物偶联物及其用于治疗癌症的用途。
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