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公开(公告)号：US20140308201A1
公开(公告)日：2014-10-16
申请号：US14204023
申请日：2014-03-11
申请人： David Bryant BATT , Seth Alexander Ettenberg , Nicole Haubst , Tiancen Hu , David Jenkins , Engin Toksoz , Konstantin Petropoulos , Matthew John Meyer
发明人： David Bryant BATT , Seth Alexander Ettenberg , Nicole Haubst , Tiancen Hu , David Jenkins , Engin Toksoz , Konstantin Petropoulos , Matthew John Meyer
CPC分类号： C07K16/2863 , A61K31/496 , A61K31/5025 , A61K31/506 , A61K31/662 , A61K45/06 , A61K47/48384 , A61K47/48561 , A61K47/6803 , A61K47/6849 , A61K2039/505 , C07K2317/565 , C07K2317/732 , C07K2317/92 , A61K2300/00
摘要： The present invention relates to anti-FGFR2 antibodies, antibody fragments, antibody drug conjugates, and their uses for the treatment of cancer.
摘要翻译： 本发明涉及抗FGFR2抗体，抗体片段，抗体药物偶联物及其用于治疗癌症的用途。
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公开(公告)号：US20160046711A1
公开(公告)日：2016-02-18
申请号：US14820897
申请日：2015-08-07
申请人： Carl Uli BIALUCHA , Scott COLLINS , Clemens DÜRR , Tiancen HU , Mary Jo JANATPOUR , Matthew John MEYER
发明人： Carl Uli BIALUCHA , Scott COLLINS , Clemens DÜRR , Tiancen HU , Mary Jo JANATPOUR , Matthew John MEYER
IPC分类号： C07K16/28 , A61K47/48 , A61K45/06 , G01N33/574
CPC分类号： C07K16/28 , A61K31/4738 , A61K45/06 , A61K47/6803 , A61K47/6849 , A61K47/6889 , A61K2039/505 , C07K2317/21 , C07K2317/34 , C07K2317/40 , C07K2317/55 , C07K2317/56 , C07K2317/73 , C07K2317/92 , G01N33/57492 , G01N2333/705 , A61K2300/00 , A61K39/395
摘要： The present invention relates to anti-CDH6 antibodies, antibody fragments, antibody drug conjugates, and their uses for the treatment of cancer.
摘要翻译： 本发明涉及抗CDH6抗体，抗体片段，抗体药物偶联物及其用于治疗癌症的用途。
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公开(公告)号：US20180207273A1
公开(公告)日：2018-07-26
申请号：US15747326
申请日：2016-07-28
申请人： Glenn Dranoff , Catherine Anne Sabatos-Peyton , Barbara Brannetti , Alan S. Harris , Thomas Huber , Thomas Pietzonka , Jennifer Marie Mataraza , Walter A. Blattler , Daniel J. Hicklin , Maximiliano Vasquez , Rosemarie H. DeKruyff , Dale T. Umetsu , Gordon James Freeman , Tiancen Hu , John A. Taraszka , Fangmin Xu , Novartis AG , DANA-FARBER CANCER INSTITUTE, INC. , Children's Medical Center Corporation
发明人： Glenn Dranoff , Catherine Anne Sabatos-Peyton , Barbara Brannetti , Alan S. Harris , Thomas Huber , Thomas Pietzonka , Jennifer Marie Mataraza , Walter A. Blattler , Daniel J. Hicklin , Maximiliano Vasquez , Rosemarie H. DeKruyff , Dale T. Umetsu , Gordon James Freeman , Tiancen Hu , John A. Taraszka , Fangmin Xu
IPC分类号： A61K39/395 , A61K45/06 , A61P35/00
CPC分类号： A61K39/39566 , A61K39/00 , A61K39/3955 , A61K45/06 , A61K2039/507 , A61P35/00 , C07K16/2803 , C07K2299/00 , C07K2317/24 , C07K2317/34 , C07K2317/76 , C07K2317/94 , A61K2300/00
摘要： Combination therapies comprising antibody molecules that specifically bind to TIM-3 are disclosed. The combination therapies can be used to treat or prevent cancerous or infectious conditions and disorders.
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公开(公告)号：US09982045B2
公开(公告)日：2018-05-29
申请号：US14820897
申请日：2015-08-07
申请人： Carl Uli Bialucha , Scott Collins , Clemens Dürr , Tiancen Hu , Mary Jo Janatpour , Matthew John Meyer
发明人： Carl Uli Bialucha , Scott Collins , Clemens Dürr , Tiancen Hu , Mary Jo Janatpour , Matthew John Meyer
IPC分类号： A61K47/48 , C07K16/28 , G01N33/574 , A61K45/06 , A61K31/4738 , A61K47/68 , A61K39/00
CPC分类号： C07K16/28 , A61K31/4738 , A61K45/06 , A61K47/6803 , A61K47/6849 , A61K47/6889 , A61K2039/505 , C07K2317/21 , C07K2317/34 , C07K2317/40 , C07K2317/55 , C07K2317/56 , C07K2317/73 , C07K2317/92 , G01N33/57492 , G01N2333/705 , A61K2300/00 , A61K39/395
摘要： The present invention relates to anti-CDH6 antibodies, antibody fragments, antibody drug conjugates, and their uses for the treatment of cancer.
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公开(公告)号：US10238748B2
公开(公告)日：2019-03-26
申请号：US15502478
申请日：2015-08-07
申请人： Carl Uli Bialucha , Scott Collins , Clemens Dürr , Tiancen Hu , Mary Jo Janatpour , Matthew John Meyer
发明人： Carl Uli Bialucha , Scott Collins , Clemens Dürr , Tiancen Hu , Mary Jo Janatpour , Matthew John Meyer
IPC分类号： A61K39/395 , A61K47/48 , C07K16/28 , A61K31/537 , A61K31/635 , A61K31/428 , A61K38/05 , A61K31/519 , C07K16/30
摘要： The present invention relates to anti-CDH6 antibodies, antibody fragments, antibody drug conjugates, and their uses for the treatment of cancer.
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公开(公告)号：US20170106095A1
公开(公告)日：2017-04-20
申请号：US15291024
申请日：2016-10-11
申请人： David Bryant BATT , Seth Alexander Ettenberg , Nicole Haubst , Tiancen Hu , David Jenkins , Engin Toksoz , Konstantin Petropoulos , Matthew John Meyer
发明人： David Bryant BATT , Seth Alexander Ettenberg , Nicole Haubst , Tiancen Hu , David Jenkins , Engin Toksoz , Konstantin Petropoulos , Matthew John Meyer
IPC分类号： A61K39/00 , C07K16/30 , A61K31/506 , C07K16/28 , A61K45/06
CPC分类号： C07K16/30 , A61K31/506 , A61K45/06 , A61K47/549 , A61K47/6803 , A61K47/6849 , A61K47/6879 , A61K2039/505 , C07K16/2863 , C07K16/3015 , C07K16/3023 , C07K16/303 , C07K16/3038 , C07K16/3046 , C07K16/3069 , C07K2317/21 , C07K2317/31 , C07K2317/33 , C07K2317/34 , C07K2317/52 , C07K2317/55 , C07K2317/565 , C07K2317/73 , C07K2317/732 , C07K2317/75 , C07K2317/76 , C07K2317/92 , C07K2319/00
摘要： The present invention relates to anti-FGFR2 and FGFR4 antibodies, antibody fragments, antibody drug conjugates, and their uses for the treatment of cancer.
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公开(公告)号：US20170008964A1
公开(公告)日：2017-01-12
申请号：US15204210
申请日：2016-07-07
申请人： David Bryant Batt , Seth Alexander Ettenberg , Nicole Haubst , Tiancen HU , David Jenkins , Matthew John Meyer , Konstantin Petropoulos , Engin Toksoz
发明人： David Bryant Batt , Seth Alexander Ettenberg , Nicole Haubst , Tiancen HU , David Jenkins , Matthew John Meyer , Konstantin Petropoulos , Engin Toksoz
IPC分类号： C07K16/28 , A61K31/506 , A61K47/48
CPC分类号： C07K16/2863 , A61K31/496 , A61K31/5025 , A61K31/506 , A61K31/662 , A61K45/06 , A61K47/6803 , A61K47/6849 , A61K2039/505 , C07K2317/565 , C07K2317/732 , C07K2317/92 , A61K2300/00
摘要： The present invention relates to anti-FGFR2 antibodies, antibody fragments, antibody drug conjugates, and their uses for the treatment of cancer.
摘要翻译： 本发明涉及抗FGFR2抗体，抗体片段，抗体药物偶联物及其用于治疗癌症的用途。
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公开(公告)号：US09498532B2
公开(公告)日：2016-11-22
申请号：US14203997
申请日：2014-03-11
申请人： David Bryant Batt , Seth Alexander Ettenberg , Nicole Haubst , Tiancen Hu , David Jenkins , Engin Toksoz , Konstantin Petropoulos , Matthew John Meyer
发明人： David Bryant Batt , Seth Alexander Ettenberg , Nicole Haubst , Tiancen Hu , David Jenkins , Engin Toksoz , Konstantin Petropoulos , Matthew John Meyer
CPC分类号： C07K16/30 , A61K31/506 , A61K45/06 , A61K47/549 , A61K47/6803 , A61K47/6849 , A61K47/6879 , A61K2039/505 , C07K16/2863 , C07K16/3015 , C07K16/3023 , C07K16/303 , C07K16/3038 , C07K16/3046 , C07K16/3069 , C07K2317/21 , C07K2317/31 , C07K2317/33 , C07K2317/34 , C07K2317/52 , C07K2317/55 , C07K2317/565 , C07K2317/73 , C07K2317/732 , C07K2317/75 , C07K2317/76 , C07K2317/92 , C07K2319/00
摘要： The present invention relates to anti-FGFR2 and FGFR4 antibodies, antibody fragments, antibody drug conjugates, and their uses for the treatment of cancer.
摘要翻译： 本发明涉及抗FGFR2和FGFR4抗体，抗体片段，抗体药物偶联物及其用于治疗癌症的用途。
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公开(公告)号：US20140301946A1
公开(公告)日：2014-10-09
申请号：US14203997
申请日：2014-03-11
申请人： David Bryant BATT , Seth Alexander Ettenberg , Nicole Haubst , Tiancen Hu , David Jenkins , Engin Toksoz , Konstantin Petropoulos , Matthew John Meyer
发明人： David Bryant BATT , Seth Alexander Ettenberg , Nicole Haubst , Tiancen Hu , David Jenkins , Engin Toksoz , Konstantin Petropoulos , Matthew John Meyer
CPC分类号： C07K16/30 , A61K31/506 , A61K45/06 , A61K47/549 , A61K47/6803 , A61K47/6849 , A61K47/6879 , A61K2039/505 , C07K16/2863 , C07K16/3015 , C07K16/3023 , C07K16/303 , C07K16/3038 , C07K16/3046 , C07K16/3069 , C07K2317/21 , C07K2317/31 , C07K2317/33 , C07K2317/34 , C07K2317/52 , C07K2317/55 , C07K2317/565 , C07K2317/73 , C07K2317/732 , C07K2317/75 , C07K2317/76 , C07K2317/92 , C07K2319/00
摘要： The present invention relates to anti-FGFR2 and FGFR4 antibodies, antibody fragments, antibody drug conjugates, and their uses for the treatment of cancer.
摘要翻译： 本发明涉及抗FGFR2和FGFR4抗体，抗体片段，抗体药物偶联物及其用于治疗癌症的用途。
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