公开(公告)号：US5478622A

公开(公告)日：1995-12-26

申请号：US253831

申请日：1994-06-03

申请人： Kouichi Nakamura ,  Hirotsugu Kodama ,  Kyoji Noda

发明人： Kouichi Nakamura ,  Hirotsugu Kodama ,  Kyoji Noda

IPC分类号： G11B5/72 ,  G11B5/64 ,  G11B5/73 ,  G11B5/738 ,  G11B5/82 ,  G11B5/84 ,  G11B21/21 ,  B05D5/12

CPC分类号： G11B5/7325 ,  G11B5/82 ,  G11B5/8404 ,  G11B21/21 ,  Y10S428/90 ,  Y10T428/24537 ,  Y10T428/24545 ,  Y10T428/31

摘要： A magnetic disk includes two kinds of texture lines formed on a substrate rendered to texturing, one kind being formed over the entire substrate and parallel with a circumference of the substrate and the other kind being formed such that a line tangent to the other texture intersects a line tangent to the one texture at an angle of 3 to 9 degrees. The other texture lines are yielded by processing the substrate with a polishing tape rocking the substrate radially thereof, and satisfying the floating characteristic of a magnetic head as being floated in a low degree, the contact-start-stop characteristic, and the attraction characteristic.

摘要翻译： 磁盘包括形成在纹理上的基板上的两种纹理线，一种形成在整个基板上并平行于基板的周边，另一种形成为使得与另一个纹理相切的线与 线以3至9度的角度与一个纹理相切。 其他纹理线通过用抛光带处理衬底而产生，该抛光带径向地摆动衬底，并且满足磁头的浮动特性为低浮动，接触开始 - 停止特性和吸引特性。

公开(公告)号：US06251897B1

公开(公告)日：2001-06-26

申请号：US09230869

申请日：1999-02-01

申请人： Shinji Ina ,  Kenjirou Yamana ,  Kyoji Noda

发明人： Shinji Ina ,  Kenjirou Yamana ,  Kyoji Noda

IPC分类号： A61K31535

CPC分类号： C07D413/04 ,  C07D265/10 ,  C07D413/06 ,  C07D413/12 ,  C07D417/04 ,  C07D417/12

摘要： A 6-phenyltetrahydro-1,3-oxazin-2-one derivative having the formula (I): wherein, R1 is an unsubstituted or substituted C1 to C8 alkyl group; an unsubstituted or substituted C3 to C7 cycloalkyl group;, etc., R2 is a C1 to C4 alkyl group, R3 is H; an unsubstituted or substituted C1 to C5 alkyl group; etc., R4 is H; an unsubstituted or substituted C1 to C6 alkyl group, and R5 and R6 are independently a hydrogen atom; an unsubstituted or substituted C1 to C5 alkyl group; etc. an optical isomer thereof, or a pharmacologically acceptable salt thereof, or a hydrate or a solvate thereof and pharmaceutical compositions containing the same, in particular a drug for the prevention or treatment of inflammatory diseases and a drug for asthma. The above 6-phenyltetrahydro-1,3-oxazin-2-one derivative has a strong type IV PDE inhibitory activity and has a bronchiodilator and antiinflammatory effects.

摘要翻译： 具有式（I）的6-苯基四氢-1,3-恶嗪-2-酮衍生物：其中，R1是未取代或取代的C1至C8烷基; 未取代或取代的C 3〜C 7环烷基等; R 2为C 1〜C 4烷基，R 3为H; 未取代或取代的C1至C5烷基; 等等，R4是H; 未取代或取代的C1至C6烷基，R5和R6独立地为氢原子; 未取代或取代的C1至C5烷基; 其光学异构体或其药理学上可接受的盐，或其水合物或溶剂化物以及含有它们的药物组合物，特别是用于预防或治疗炎性疾病的药物和用于哮喘的药物。 苯基四氢-1,3-恶嗪-2-酮衍生物具有强IV型PDE抑制活性，具有支气管扩张剂和抗炎作用。

公开(公告)号：US06265402B1

公开(公告)日：2001-07-24

申请号：US09242818

申请日：1999-02-25

申请人： Shinji Ina ,  Kenjirou Yamana ,  Kyoji Noda

发明人： Shinji Ina ,  Kenjirou Yamana ,  Kyoji Noda

IPC分类号： A61K315375

CPC分类号： C07D413/06 ,  C07D265/32

摘要： A 2-phenylmorpholin-5-one derivative having the formula (I): wherein R1 represents a C1 to C8 alkyl group, a C3 to C7 cycloalkyl group or an indanyl group, R2 represents a C1 to C4 alkyl group, R3 represents a hydrogen atom, a C1 to C5 alkyl group, etc., R4 represents a hydrogen atom, a C1 to C6 alkyl group, etc., R5, R6 represent a hydrogen atom, a C1 to C5 alkyl group, etc., an optical isomer thereof or a pharmacologically acceptable salt thereof, or a hydrate or solvate thereof and a pharmaceutical composition containing the same. The above compound has a strong type IV phosphodiesterase (PDE) inhibitory activity and has bronchodilater and antiinflammatory effects.

摘要翻译： 具有式（I）的2-苯基吗啉-5-酮衍生物：其中R1表示C1至C8烷基，C3至C7环烷基或茚满基，R2表示C1至C4烷基，R3表示氢 原子，C1〜C5烷基等，R4表示氢原子，C1〜C6烷基等，R5，R6表示氢原子，C1〜C5烷基等，其旋光异构体 或其药理学上可接受的盐，或其水合物或溶剂化物以及含有它们的药物组合物。上述化合物具有强IV型磷酸二酯酶（PDE）抑制活性并具有支气管扩张剂和抗炎作用。

公开(公告)号：US5948289A

公开(公告)日：1999-09-07

申请号：US755164

申请日：1996-11-25

申请人： Kyoji Noda ,  Shunichi Uchinami

发明人： Kyoji Noda ,  Shunichi Uchinami

IPC分类号： B41J2/135 ,  B23K26/06

CPC分类号： B23K26/066

摘要： A laser beam machining method includes emitting light from a light source to illuminate a mask which has both openings through which light can pass to the object to be machined and blocking parts through which substantially no light can pass. By utilizing the energy of the light, those portions of the object which are exposed through the openings are machined by ablation. The shape and width of both the openings and the blocking parts can be adjusted so as to provide the energy distribution required to form an object of the desired shape and size.

摘要翻译： 激光束加工方法包括从光源发射光以照亮具有光可以通过的两个开口的掩模到待加工物体的阻挡部件和基本上不能通过的阻挡部件。 通过利用光的能量，通过开口暴露的物体的那些部分通过消融加工。 可以调节开口和阻挡部分的形状和宽度，以便提供形成所需形状和尺寸的物体所需的能量分布。

公开(公告)号：US4687712A

公开(公告)日：1987-08-18

申请号：US678040

申请日：1984-12-04

申请人： Ryuji Sugita ,  Kazuyoshi Honda ,  Hiroshi Nishida ,  Kyoji Noda

发明人： Ryuji Sugita ,  Kazuyoshi Honda ,  Hiroshi Nishida ,  Kyoji Noda

IPC分类号： G11B5/66

CPC分类号： G11B5/66 ,  Y10S428/928 ,  Y10T428/12465 ,  Y10T428/12632 ,  Y10T428/12806 ,  Y10T428/12861 ,  Y10T428/12931 ,  Y10T428/12937

摘要： A vertical magnetic recording medium comprises a non-magnetic substrate, a permalloy film consisting of plural permalloy layers separated by at least one non-magnetic layer placed therein, each of said plurality of permalloy layers being 2000 .ANG. or less thick, and a Co-Cr vertical magnetization film formed on the permalloy film directly or through another non-magnetic layer.

摘要翻译： 垂直磁记录介质包括非磁性基板，由多个坡莫合金层组成的坡莫合金膜，所述多个坡莫合金层由放置在其中的至少一个非磁性层分开，所述多个坡莫合金层中的每一个为2000或更小， Cr垂直磁化膜直接或通过另一个非磁性层形成在坡莫合金膜上。

公开(公告)号：US06235739B1

公开(公告)日：2001-05-22

申请号：US09202317

申请日：1998-12-11

申请人： Shinji Ina ,  Kenjirou Yamana ,  Kyoji Noda

发明人： Shinji Ina ,  Kenjirou Yamana ,  Kyoji Noda

IPC分类号： A61K3150

CPC分类号： C07D237/04

摘要： A 5-phenyl-3-pyridazinone derivative having the formula (I) wherein R1 represents an unsubstituted or substituted C1 to C8 alkyl group, C3 to C7 cycloalkyl group, or indanyl group; R2 represents a C1 to C4 alkyl group; R3 represents a hydrogen atom or an unsubstituted or substituted C1 to C5 alkyl group; a C3 to C7 cycloalkyl group; or an aryl group which may contain a heteroatom; R4 and R5 independently represent a hydrogen atom, C1 to C6 alkyl group, an unsubstituted or substituted phenyl, or a monocyclic aryl group which may contain a heteroatom; a dotted line represents a single or double bond, provided that when the dotted line represents a single bond; R6 represents a hydrogen atom or C1 to C6 alkyl group.

摘要翻译： 具有式（I）的5-苯基-3-哒嗪酮衍生物，其中R1表示未取代或取代的C1至C8烷基，C3至C7环烷基或茚满基; R2表示C1〜C4烷基; R3表示氢原子或未取代或取代的C1至C5烷基; C3至C7环烷基; 或可以含有杂原子的芳基; R4和R5独立地表示氢原子，C1-C6烷基，未取代或取代的苯基或可含有杂原子的单环芳基; 虚线表示单键或双键，条件是当虚线表示单键时; R6表示氢原子或C1〜C6烷基。

公开(公告)号：US06235736B1

公开(公告)日：2001-05-22

申请号：US09446822

申请日：2000-03-20

申请人： Shinji Ina ,  Kenjirou Yamana ,  Kyoji Noda ,  Akane Takahama ,  Toshihiko Akiyama

发明人： Shinji Ina ,  Kenjirou Yamana ,  Kyoji Noda ,  Akane Takahama ,  Toshihiko Akiyama

IPC分类号： A61K31136

CPC分类号： C07D295/116 ,  C07C225/20 ,  C07C225/22 ,  C07C2601/02 ,  C07C2601/08 ,  C07C2601/16 ,  C07C2602/08 ,  C07C2602/42 ,  C07D211/86 ,  C07D213/38 ,  C07D215/12 ,  C07D307/20

摘要： A 3-anilino-2-cycloalkenone derivative of the formula (I): wherein, R1 represents a C1 to C8 alkyl group, which may have a substituent, except for a methyl group, a C3 to C7 cycloalkyl group, a 3-tetrahydrofuryl group, an 2-indanyl group, etc., R2 represents a C1 to C4 alkyl group, R3 represents a hydrogen atom, a C3 to C7 alkyl group, which may have a substituent, a C3 to C7 cycloalkyl group, etc., R4 represents a hydrogen atom, a C1 to C5 alkyl group, which may have a substituent, a halogen atom, etc., R5, R6, R7, and R8 independently represent a hydrogen atom, a C1 to C5 alkyl group, which may have a substituent, etc., X represents —(CR11R12)n—, wherein n is 0 to 2, R11 and R12 independently represent a hydrogen atom, a C1 to C5 alkyl group, which may have a substituent, etc. or —NR13— wherein R13 represents a hydrogen atom or a C1 to C5 alkyl group, which may have a substituent, and its optical isomers or their pharmaceutically acceptable salts or their hydrates or solvates.

摘要翻译： 式（I）的3-苯胺基-2-环烯酮酮衍生物：其中，R 1表示可以具有取代基的C1〜C8烷基，除了甲基，C3〜C7环烷基，3-四氢呋喃基 基，1,2-二氢化茚基等，R2表示C1〜C4烷基，R3表示氢原子，可具有取代基的C3〜C7烷基，C3〜C7环烷基等，R4 表示氢原子，可具有取代基的C1〜C5烷基，卤素原子等，R5，R6，R7和R8分别表示氢原子，C1〜C5烷基，可以具有 取代基等，X表示 - （CR 11 R 12）n - ，其中n为0至2，R 11和R 12独立地表示氢原子，可具有取代基的C1至C5烷基等，或-NR13-，其中 R13表示可以具有取代基的氢原子或C1〜C5烷基，及其光学异构体或其药学上可接受的盐或其水合物或溶剂化物。