公开(公告)号：US20080152735A1

公开(公告)日：2008-06-26

申请号：US11963628

申请日：2007-12-21

Applicant: Wen-Liang Chang ,  Chen-Wen Yao ,  Ann Chen ,  Chung-Yang Yen ,  Li-Shian Shi ,  Jenn-Han Chen ,  Ching-Len Liao ,  Kuo-Yuan Hwa ,  An-Rong Lee ,  Po-Huang Liang

Inventor： Wen-Liang Chang ,  Chen-Wen Yao ,  Ann Chen ,  Chung-Yang Yen ,  Li-Shian Shi ,  Jenn-Han Chen ,  Ching-Len Liao ,  Kuo-Yuan Hwa ,  An-Rong Lee ,  Po-Huang Liang

IPC: A61K36/236 ,  A61K36/00 ,  A61K36/489 ,  A61K31/352 ,  A61P31/12

CPC classification number: A61K36/484 ,  A61K31/352 ,  A61K36/236 ,  A61K36/489

Abstract: The invention provides a herbal extract having anti-influenza virus activity, by extracting Sophora flavescens Ait, Thesium chinense Turcz, licorice, or mixture thereof with solvent. The herbal extract contains at least one compound selected from the group of compounds represented by following formula (I) or (II) or mixture thereof:

Abstract translation: 本发明提供了具有抗流感病毒活性的草药提取物，通过提取苦参，枸杞，甘草或其与溶剂的混合物。 草药提取物含有至少一种选自由下式（I）或（II）表示的化合物或其混合物的化合物：

公开(公告)号：US20130109036A1

公开(公告)日：2013-05-02

申请号：US13284812

申请日：2011-10-28

Applicant: YI-LING YE ,  LI-SHIAN SHI ,  LIN-YI WU ,  I-EN LIN ,  JENG-HAUR HORNG ,  L. JAMES LEE

Inventor： YI-LING YE ,  LI-SHIAN SHI ,  LIN-YI WU ,  I-EN LIN ,  JENG-HAUR HORNG ,  L. JAMES LEE

IPC: G01N33/53 ,  C12P21/00

CPC classification number: G01N33/54353

Abstract: A protein substrate includes a base having micro-passages and reaction grooves, a polyethyleneimine (PEI) fixed on the base and a specific protein fixed on the PEI. The base is modified by plasma stripper to make the PEI bonded on the base. Mixed with tyrosinase, the specific protein can stably stick on the base due to the tyrosinase bonded with the PEI. By antigen-antibody bonding specificity, the invention can quickly detect antibody in a sample able to link with the specific protein. The specific antibody can be added with targeted biotin secondary antibody, targeted avidin-peroxidase, and color producing substrate able to react with the targeted avidin-peroxidase, such as tetramethylbenzidine or 3-(4-hydroxy)phenyl propionic acid (HPPA), so as to measure a specific antibody amount.

Abstract translation: 蛋白质底物包括具有微通道和反应槽的基底，固定在基底上的聚乙烯亚胺（PEI）和固定在PEI上的特定蛋白质。 基体由等离子体汽提器改性，使PEI结合在基体上。 与酪氨酸酶混合，由于与PEI结合的酪氨酸酶，特异性蛋白质可以稳定地粘在基质上。 通过抗原 - 抗体结合特异性，本发明可以快速检测能够与特异性蛋白质连接的样品中的抗体。 特异性抗体可以加入靶向的生物素二抗，靶向的抗生物素蛋白 - 过氧化物酶和能够与靶向的抗生物素蛋白 - 过氧化物酶如四甲基联苯胺或3-（4-羟基）苯基丙酸（HPPA）反应的产生色素的底物，因此 以测量特异性抗体量。