公开(公告)号：US09076314B2

公开(公告)日：2015-07-07

申请号：US11837921

申请日：2007-08-13

申请人： Landon C. G. Miller

发明人： Landon C. G. Miller

IPC分类号： G08B23/00 ,  G08B25/00

CPC分类号： G08B25/009

摘要： Emergent information is created and utilized by an array of sensors. Each sensor is programmed with a trigger rule, which describes a local condition that must be met for the sensor to trigger an event signal, and a relationship rule, which describes a hierarchy of communication control among sensors in the array of sensors. When a predetermined percentage or weighting of the sensors trigger event signals, emergent information that describes conditions at the array location is generated.

摘要翻译： 紧急信息由一组传感器创建和利用。 每个传感器都用触发规则进行编程，该规则描述了传感器触发事件​​信号必须满足的局部条件，以及描述传感器阵列中的传感器之间的通信控制层级的关系规则。 当传感器的预定百分比或加权触发事件信号时，产生描述阵列位置处的条件的紧急信息。

公开(公告)号：US08712987B2

公开(公告)日：2014-04-29

申请号：US11837955

申请日：2007-08-13

申请人： Landon C. G. Miller

发明人： Landon C. G. Miller

IPC分类号： G06F7/00 ,  G06F17/30

CPC分类号： G06F17/30286 ,  G06N5/025

摘要： A method for recreating known emergent information comprises initially storing data in a database. Multiple data patterns, which are based on known emergent information, are developed. These multiple data patterns are ranked according to each data pattern's historic accuracy in creating the known emergent information. The data is applied to a highest-ranked data pattern to recreate the known emergent information.

摘要翻译： 重新创建已知的紧急信息的方法包括将数据初始地存储在数据库中。 开发了基于已知紧急信息的多种数据模式。 这些多个数据模式根据每个数据模式在创建已知紧急信息中的历史准确性进行排名。 将数据应用于最高排名的数据模式，以重建已知的紧急信息。

公开(公告)号：US20120150980A1

公开(公告)日：2012-06-14

申请号：US13397250

申请日：2012-02-15

申请人： LANDON C. G. MILLER ,  SILJAN H. SIMPSON

发明人： LANDON C. G. MILLER ,  SILJAN H. SIMPSON

IPC分类号： G06F15/16

CPC分类号： G06Q10/06

摘要： A processor-implemented method, system, and/or computer program product integrate Service Oriented Architecture (SOA) services with resources at multiple enterprises. A processor receives and aggregates trapped messages, from an affected resource, which describe an event. The trapped aggregated message describes redundant messages about a same event. The trapped aggregated message is transcribed to create a transcribed trapped aggregated message, which is transmitted to the SOA response service to request the pre-set response. The pre-set response is translated into a protocol needed to initiate the pre-set response in an electronic element referenced by the pre-set response, and is then transmitted to the electronic element.

摘要翻译： 处理器实现的方法，系统和/或计算机程序产品将面向服务的架构（SOA）服务与多个企业的资源集成。 处理器从受影响的资源接收和聚合被捕获的消息，描述事件。 被捕获的聚合消息描述有关相同事件的冗余消息。 被捕获的聚合消息被转录以创建转录的被捕获的聚合消息，其被传送到SOA响应服务以请求预设响应。 预设响应被转换为在由预设响应引用的电子元件中启动预置响应所需的协议，然后被传送到电子元件。

公开(公告)号：US07979088B2

公开(公告)日：2011-07-12

申请号：US11837886

申请日：2007-08-13

申请人： Landon C. G. Miller

发明人： Landon C. G. Miller

IPC分类号： H04B1/38

CPC分类号： G01S13/78 ,  G01V15/00

摘要： Disclosed are a method, system, and computer program product for a Water Friend or Foe System (WFSS) including a Subscriber Identity Module (SIM) card in a SIM reader on a marine vessel. The WFFS system on the marine vessel transmits secure identity information and location information to a WFFS tracking station. The WFFS system on the marine vessel detects anomalies on the marine vessel and in response transmits an alarm signal to a WFFS tracking station and/or shuts down a propulsion system of the marine vessel. The WFFS system on the marine vessel can also receive a one-time “override” encrypted code to re-enable ship control of the propulsion system. The secure identity information and real-time vessel location are transmitted in one of: an Automatic Identifier System (AIS) message type or a Global Maritime Distress Safety System (GMDSS) message type.

摘要翻译： 公开了一种用于水上朋友或敌对系统（WFSS）的方法，系统和计算机程序产品，其包括船上SIM读卡器中的用户识别模块（SIM）卡。 船上的WFFS系统将安全身份信息和位置信息传送到WFFS跟踪站。 海上船只上的WFFS系统检测船上的异常情况，并响应向WFFS跟踪站传送报警信号和/或关闭海上船只的推进系统。 船上的WFFS系统也可以收到一次“超越”加密代码，以重新启用推进系统的船舶控制。 安全身份信息和实时船舶位置以自动识别系统（AIS）消息类型或全球海上遇险安全系统（GMDSS）消息类型中的一种发送。

公开(公告)号：US07889100B2

公开(公告)日：2011-02-15

申请号：US11838637

申请日：2007-08-14

申请人： Landon C. G. Miller

发明人： Landon C. G. Miller

IPC分类号： G08B23/00 ,  G08G3/00 ,  G01S13/78

CPC分类号： G08G3/00

摘要： A Water Friend or Foe System (WFSS) includes a Subscriber Identity Module (SIM) card in a SIM reader on a marine vessel. A transmitter, which is coupled to the SIM reader, transmits information from the SIM card, as well as positioning information, to a WFFS tracking station.

摘要翻译： 水朋友或敌对系统（WFSS）在海运船上的SIM卡读卡器中包括用户识别模块（SIM）卡。 耦合到SIM读卡器的发射器将信息从SIM卡传送到定位信息到WFFS跟踪站。

公开(公告)号：US07864037B2

公开(公告)日：2011-01-04

申请号：US12139723

申请日：2008-06-16

申请人： Landon C. G. Miller

发明人： Landon C. G. Miller

IPC分类号： G08B29/00

CPC分类号： G08B13/19667 ,  G08B25/14 ,  G08B31/00

摘要： A method, system and computer program product for communicating pattern data is presented. A graphical event pattern is sent to an interconnected array of intelligent sensors. When intelligent sensors in the interconnected array determine that an event has occurred, the graphical event pattern is sent to a user. Thereafter, any data that supports the graphical event pattern is sent to the user. Thus, this supporting data is transmitted according to the graphical event pattern, rather than a header address.

摘要翻译： 提出了一种用于传送模式数据的方法，系统和计算机程序产品。 图形事件模式被发送到互连的智能传感器阵列。 当互连阵列中的智能传感器确定事件已发生时，图形事件模式将发送给用户。 此后，将支持图形事件模式的任何数据发送给用户。 因此，根据图形事件模式而不是标题地址来发送该支持数据。

公开(公告)号：US07756593B2

公开(公告)日：2010-07-13

申请号：US11838739

申请日：2007-08-14

申请人： Landon C. G. Miller

发明人： Landon C. G. Miller

IPC分类号： G05B9/02 ,  G05B13/02 ,  G05B21/02 ,  G05B23/02 ,  G06F11/30 ,  G06F3/048

CPC分类号： G08B19/00 ,  G08B21/12

摘要： A method is presented for representing anomalies to a process. These anomalies are represented in an anti-pattern, which depicts non-productive emergent information that describes activities that are detrimental to the progress of the process. The anti-pattern includes visually-coded areas that describe how severe the detrimental activities are to the process when combined. After the anti-pattern is created for the process, new non-productive emergent information for a current process is mapped onto the anti-pattern in the form of data patterns represented as visual fences. Appropriate steps are then taken to address the new non-productive emergent information, depending on the visually-coded area to which the new non-productive emergent information is mapped.

摘要翻译： 提出了一种用于表示过程异常的方法。 这些异常表现为反模式，其描绘了非生产性紧急信息，其描述对过程进展有害的活动。 反模式包括视觉编码的区域，描述了组合时对过程的有害活动的严重程度。 在为该过程创建反模式之后，用于当前进程的新的非生产性紧急信息以表示为视觉围栏的数据模式的形式被映射到反模式上。 然后采取适当的步骤来解决新的非生产性紧急信息，这取决于新的非生产性紧急信息被映射到的视觉编码区域。

公开(公告)号：US07710260B2

公开(公告)日：2010-05-04

申请号：US11838695

申请日：2007-08-14

申请人： Landon C. G. Miller

发明人： Landon C. G. Miller

IPC分类号： G08B19/00

CPC分类号： G08B25/14

摘要： Emergent information is created and utilized by an array of sensors. Each sensor is programmed with a trigger rule, which describes a local condition that must be met for the sensor to trigger an event signal, and a relationship rule, which describes a hierarchy of communication control among sensors in the array of sensors. When a predetermined weighted percentage of the sensors trigger event signals, emergent information that describes conditions at the array location is generated. An effectuator then takes appropriate steps to address the condition described by the emergent information.

摘要翻译： 紧急信息由一组传感器创建和利用。 每个传感器都用触发规则进行编程，该规则描述了传感器触发事件​​信号必须满足的局部条件，以及描述传感器阵列中的传感器之间的通信控制层级的关系规则。 当传感器的预定加权百分比触发事件信号时，产生描述阵列位置处的条件的紧急信息。 然后，效果器采取适当的步骤来解决紧急信息描述的状况。

公开(公告)号：US07151084B2

公开(公告)日：2006-12-19

申请号：US11023240

申请日：2004-12-27

申请人： Landon C. G. Miller

发明人： Landon C. G. Miller

IPC分类号： A61K38/02

CPC分类号： A61K47/62 ,  A61K38/00 ,  A61K47/52 ,  A61K47/542

摘要： A complex is provided for the treatment of neurogenic conditions having the formula: where R1 is M is a metal ion Ca(II), Mg(II), Cu(II) or Ni(II); n is an integer 1 or 2; R is BBB peptide, transferrin, membrane transporter peptide, TAT peptide, bradykinin, beta-endorphin, bombesin, calcitonin, cholecystokinin, an enkephalin, dynorphin, insulin, gastrin, substance P, neurotensin, glucagon, secretin, somatostatin, motilin, vasopressin, oxytocin, prolactin, thyrotropin, an angiotensin, galanin, neuropeptide Y, thyrotropin-releasing hormone, gonadotropnin-releasing hormone, growth hormone-releasing hormone, luteinizing hormone, vasoactive intestinal peptidegluconate, L-lactate, L-leucine, L-tryptophan, and L-glutamate; and R is coupled to M through a carboxylate moiety. Magnesium(II) represents the preferred metal ion as magnesium is known to have neuroprotective effects. The metal ion is in part chelated by a non-steroidal anti-inflammatory drug that does not inhibit platelet activity and includes salicylate and ibuprofenate. The complex also includes a ligand operative in transport across the blood brain barrier. A process for making an inventive complex includes the stoichiometric addition of ligands containing carboxylate groups to a solution of the metal ion. In instances where the metal ion is magnesium(II), a stoichiometric ratio of 1:1:1 is found between the non-steroidal anti-inflammatory ligand:magnesium(II):transporter ligand.

摘要翻译： 提供了用于治疗具有下式的神经源性病症的复合物：其中R 1是M是金属离子Ca（II），Mg（II），Cu（II）或Ni（II）; n是整数1或2; R是BBB肽，转铁蛋白，膜转运蛋白肽，TAT肽，缓激肽，β-内啡肽，铃蟾肽，降钙素，缩胆囊素，脑啡肽，强啡肽，胰岛素，胃泌素，物质P，神经丝氨酸，胰高血糖素，促泌素，生长抑素，胃动素， 催产素，催乳素，促甲状腺素，血管紧张素，甘丙肽，神经肽Y，促甲状腺激素释放激素，促性腺激素释放激素，生长激素释放激素，黄体生成素，血管活性肠肽葡萄糖酸盐，L-乳酸盐，L-亮氨酸，L-色氨酸和 L-谷氨酸 并且R通过羧酸酯部分与M偶联。 镁（II）代表优选的金属离子，因为已知镁具有神经保护作用。 金属离子部分被不抑制血小板活性的非甾体抗炎药螯合，包括水杨酸和布洛芬酯。 该复合物还包括在血脑屏障中运输的配体。 制备本发明复合物的方法包括向金属离子的溶液中含有羧酸酯基团的配体的化学计量加成。 在金属离子为镁（II）的情况下，在非甾体抗炎配体：镁（II）：转运体配体之间发现化学计量比为1:1:1。

公开(公告)号：US08420593B1

公开(公告)日：2013-04-16

申请号：US11764398

申请日：2007-06-18

申请人： Landon C. G. Miller

发明人： Landon C. G. Miller

IPC分类号： A01N61/00 ,  A61K31/00

CPC分类号： A61K31/529 ,  A61K31/167 ,  A61K31/428 ,  A61K31/4375 ,  A61K31/44 ,  A61K31/4409 ,  A61K45/06 ,  A61K47/50 ,  A61K2300/00

摘要： Compositions are described according to embodiments of the present invention which include a neuronal potassium channel antagonist and a neuronal sodium channel antagonist, the neuronal potassium channel antagonist and the neuronal sodium channel antagonist each conjugated to a transporter moiety to form one or more conjugates. The transporter moiety is capable of crossing the blood/brain or blood/nerve barrier such that the conjugate is delivered to the brain and/or nerve. Inventive methods of treating a demyelinating condition in a subject are described herein which include administering an effective amount of a conjugate composition of the present invention to a subject having a demyelinating condition.

摘要翻译： 根据本发明的实施方案描述了组合物，其包括神经元钾通道拮抗剂和神经元钠通道拮抗剂，神经元钾通道拮抗剂和神经元钠通道拮抗剂，其与转运蛋白部分缀合以形成一种或多种缀合物。 转运蛋白部分能够穿过血液/脑或血液/神经屏障，使得缀合物被递送到脑和/或神经。 本文描述了治疗受试者脱髓鞘状况的本发明的方法，其包括向具有脱髓鞘状态的受试者施用有效量的本发明的缀合物组合物。