Peptide inhibitors of selectin binding
    1.
    发明授权
    Peptide inhibitors of selectin binding 失效
    选择蛋白结合肽抑制剂

    公开(公告)号:US5602230A

    公开(公告)日:1997-02-11

    申请号:US438475

    申请日:1995-05-10

    CPC分类号: C07K14/70564 A61K38/00

    摘要: The present invention provides novel peptides derived from portions of the sequence of amino acids 23-26 and 27-30 of P-selectin. The invention also provides pharmaceutical compositions comprising the peptides of the invention, and diagnostic and therapeutic methods utilizing the peptides and pharmaceutical compositions of the invention. The peptides of this invention can be used in the modulation or inhibition of coagulation processes or inflammatory processes.

    摘要翻译: 本发明提供衍生自P-选择蛋白的氨基酸23-26和27-30的部分序列的新型肽。 本发明还提供了包含本发明的肽的药物组合物,以及利用本发明的肽和药物组合物的诊断和治疗方法。 本发明的肽可用于调节或抑制凝血过程或炎性过程。