公开(公告)号：US20180304069A1

公开(公告)日：2018-10-25

申请号：US15768492

申请日：2015-11-03

申请人： Kanthaiah KOKA ,  Leonid M. LITVAK ,  ADVANCED BIONICS AG

发明人： Kanthaiah Koka ,  Leonid M. Litvak

IPC分类号： A61N1/05 ,  A61N1/36

CPC分类号： A61N1/0541 ,  A61B5/04845 ,  A61N1/36036

摘要： An exemplary monitoring system 1) receives a user input command to begin monitoring evoked responses that occur in response to acoustic stimulation during an insertion procedure in which a lead that is communicatively coupled to a cochlear implant is inserted into a cochlea of a patient, the lead having an array of intracochlear electrodes and an extracochlear electrode, the extracochlear electrode physically and communicatively coupled to a probe that is also communicatively coupled to the monitoring system, 2) directs, in response to the user input command, the cochlear implant to short an intracochlear electrode with the extracochlear electrode, 3) presents the acoustic stimulation to the patient, and 4) records the evoked responses that occur in response to the acoustic stimulation by using the intracochlear electrode to detect signals representative of the evoked responses and receiving the detected signals by way of the extracochlear electrode and the probe.

公开(公告)号：US09227062B2

公开(公告)日：2016-01-05

申请号：US14357896

申请日：2011-11-15

申请人： Kinuko Masaki ,  Abhijit Kulkarni ,  Aniket Saoji ,  Leonid M. Litvak

发明人： Kinuko Masaki ,  Abhijit Kulkarni ,  Aniket Saoji ,  Leonid M. Litvak

IPC分类号： A61N1/36 ,  A61N1/372 ,  A61B5/12

CPC分类号： A61N1/36032 ,  A61B5/125 ,  A61N1/36036 ,  A61N1/37235

摘要： An exemplary system for synchronizing an operation of a middle ear analyzer and a cochlear implant system includes 1) a mapping facility configured to maintain mapping data representative of an association between a plurality of sound levels and a plurality of current levels and between a plurality of frequencies and a plurality of electrodes, 2) a detection facility configured to receive an acoustic signal transmitted by the middle ear analyzer and detect a sound level and a frequency of the acoustic signal, and 3) a processing facility configured to identify, based on the mapping data, a current level associated with the detected sound level and one or more electrodes associated with the detected frequency and direct the cochlear implant system to apply electrical stimulation having the identified current level to one or more stimulation sites within a patient by way of the identified one or more electrodes.

摘要翻译： 用于同步中耳分析仪和人工耳蜗植入系统的操作的示例性系统包括：1）映射设备，被配置为维持表示多个声级与多个当前级之间以及多个频率之间的关联的映射数据 以及多个电极，2）检测设备，被配置为接收由所述中耳分析仪发送的声信号，并检测声信号的声级和频率，以及3）处理设备，其被配置为基于所述映射 数据，与检测到的声级相关联的电流水平以及与检测到的频率相关联的一个或多个电极，并且引导人工耳蜗植入系统，通过所识别的，将具有所识别的当前水平的电刺激施加到患者内的一个或多个刺激部位 一个或多个电极。

公开(公告)号：US20140330344A1

公开(公告)日：2014-11-06

申请号：US14360587

申请日：2011-12-29

申请人： Lakshmi N. Mishra ,  Leonid M. Litvak ,  Abhijit Kulkarni ,  Lee F. Hartley

发明人： Lakshmi N. Mishra ,  Leonid M. Litvak ,  Abhijit Kulkarni ,  Lee F. Hartley

IPC分类号： A61N1/36 ,  H04R25/00

CPC分类号： A61N1/36032 ,  A61N1/0541 ,  A61N1/36036 ,  H04R25/30 ,  H04R25/43 ,  H04R25/552

摘要： An exemplary system for facilitating binaural hearing by a cochlear implant patient includes 1) a spectral analysis facility configured to divide a first audio signal presented to a first ear of the patient and a second audio signal presented to a second ear of the patient into first and second sets of analysis channels, respectively, and 2) a processing facility configured to process acoustic content contained in a first analysis channel included in the first set of analysis channels and acoustic content contained in a second analysis channel included in the second set of analysis channels, mix the processed acoustic content contained in the first and second analysis channels, and direct a cochlear implant to apply electrical stimulation representative of the mixed acoustic content to the first ear by way of a stimulation channel that corresponds to the first analysis channel.

摘要翻译： 用于通过人工耳蜗植入患者促进双耳听觉的示例性系统包括1）频谱分析设备，被配置为将呈现给患者的第一耳朵的第一音频信号和呈现给患者的第二耳朵的第二音频信号分成第一和 第二组分析通道，以及2）处理设备，其被配置为处理包含在包括在第一组分析通道中的第一分析通道中的声音内容和包含在包括在第二组分析通道中的第二分析通道中的声学内容 混合包含在第一和第二分析通道中的经处理的声学内容，并且引导一个人工耳蜗植入物，通过对应于第一分析通道的刺激通道将表示混合的声音内容的电刺激施加到第一耳朵。

公开(公告)号：US08600516B2

公开(公告)日：2013-12-03

申请号：US12175151

申请日：2008-07-17

申请人： Abhijit Kulkarni ,  Leonid M. Litvak ,  Aniket Saoji

发明人： Abhijit Kulkarni ,  Leonid M. Litvak ,  Aniket Saoji

IPC分类号： A61N1/36

CPC分类号： H04R25/00 ,  A61N1/36032 ,  A61N1/36036 ,  G10L19/0212 ,  H04R2225/025 ,  H04R2225/67

摘要： Among other things, enhancing spectral contrast for a cochlear implant listener includes detecting a time domain signal. A first transformation is applied to the detected time domain signal to convert the time domain signal to a frequency domain signal. A second transformation is applied to the frequency domain signal to express the frequency domain signal as a sum of two or more components. A sensitivity of the cochlear implant listener to detect modulation of each component is obtained.

公开(公告)号：US08509907B2

公开(公告)日：2013-08-13

申请号：US13425770

申请日：2012-03-21

申请人： Leonid M. Litvak ,  Aniket Saoji

发明人： Leonid M. Litvak ,  Aniket Saoji

IPC分类号： A61N1/00

CPC分类号： A61N1/36032 ,  A61N1/0541 ,  A61N1/36036

摘要： An exemplary method includes 1) applying a main current to a first electrode disposed within a patient and associated with a first pitch, 2) concurrently applying a compensation current to a second electrode disposed within the patient and associated with a second pitch during the application of the main current, the compensation current being out-of-phase with the main current, and 3) optimizing an amount of the compensation current to result in a target pitch being presented to the patient that is distanced from the first pitch in a pitch direction opposite a pitch direction of the second pitch in relation to the first pitch. Corresponding methods and systems are also disclosed.

摘要翻译： 一种示例性方法包括：1）将主电流施加到设置在患者体内并与第一间距相关联的第一电极; 2）在应用期间同时向布置在患者体内的第二电极施加补偿电流，并与第二电极相关联 主电流，补偿电流与主电流异相，以及3）优化补偿电流的量以导致目标音调被呈现给在间距方向上与第一音调间隔的患者 相对于第一间距与第二间距的俯仰方向相反。 还公开了相应的方法和系统。

公开(公告)号：US08412340B2

公开(公告)日：2013-04-02

申请号：US12172869

申请日：2008-07-14

申请人： Leonid M. Litvak ,  Abhijit Kulkarni

发明人： Leonid M. Litvak ,  Abhijit Kulkarni

IPC分类号： A61N1/05

CPC分类号： A61N1/36032 ,  A61N1/0541 ,  A61N1/36036 ,  H04R2225/67

摘要： Methods and systems of optimizing sound sensation of a cochlear implant patient include dividing an audio signal into a plurality of analysis channels, generating one or more tonality indices each representing a tonality of one of the analysis channels, generating one or more stimulation pulses configured to represent the audio signal in accordance with one or more stimulation parameters, and adjusting at least one of the stimulation parameters based on at least one of the tonality indices.

摘要翻译： 优化耳蜗植入患者声音的方法和系统包括将音频信号划分成多个分析通道，产生一个或多个音调指数，每个音调指数表示分析通道之一的音调，产生一个或多个被配置为表示 所述音频信号根据一个或多个刺激参数，以及基于所述音调指数中的至少一个来调整所述刺激参数中的至少一个。

公开(公告)号：US08321026B2

公开(公告)日：2012-11-27

申请号：US12556972

申请日：2009-09-10

申请人： Aniket Saoji ,  Leonid M. Litvak

发明人： Aniket Saoji ,  Leonid M. Litvak

IPC分类号： A61N1/05

CPC分类号： A61N1/36036 ,  A61B5/121 ,  A61N1/37247

摘要： Methods and systems of spectral tilt optimization for a cochlear implant patient include applying electrical stimulation representative of an audio signal to a patient in accordance with a spectral tilt value and optimizing the spectral tilt value in response to a measured ability of the patient to recognize at least one attribute of the audio signal.

摘要翻译： 用于耳蜗植入患者的频谱倾斜优化的方法和系统包括根据频谱倾斜值将表示音频信号的电刺激应用于患者，并响应于患者的测量能力至少识别至少 音频信号的一个属性。

公开(公告)号：US20120197346A1

公开(公告)日：2012-08-02

申请号：US13444655

申请日：2012-04-11

申请人： Leonid M. Litvak ,  Lakshmi N. Mishra

发明人： Leonid M. Litvak ,  Lakshmi N. Mishra

IPC分类号： A61F11/04 ,  A61N1/36

CPC分类号： A61N1/37247 ,  A61N1/36036 ,  H04R2225/67

摘要： Errors in pitch allocation within a cochlear implant are corrected in order to provide a significant and profound improvement in the quality of sound perceived by the cochlear implant user. The disclosure provides a tool for determining the implant fitting curve for cochlear implant system to correct pitch warping. The method presents familiar musical tunes to determine the implant fitting slope (relative alignment). In addition, in one embodiment, speech sounds may be used to determine the offset of the fitting line (absolute alignment). The use of music and speech to determine the implant fitting curve (line) and the slope is facilitated by using techniques to implement virtual electrodes to more precisely direct stimuli to the location or “place” on the cochlea.

摘要翻译： 修正耳蜗植入物内音调分配的错误，以便对耳蜗植入物使用者感知到的声音质量进行显着和深刻的改进。 本公开提供了一种用于确定用于人工耳蜗植入系统的植入物拟合曲线以校正间距翘曲的工具。 该方法呈现熟悉的音乐曲调以确定植入物拟合斜率（相对对准）。 此外，在一个实施例中，可以使用语音来确定拟合线的偏移（绝对对准）。 通过使用技术来实现虚拟电极以更精确地将刺激直接引导到耳蜗上的位置或“位置”来促进使用音乐和言语来确定植入物拟合曲线（线）和斜率。

公开(公告)号：US20120179224A1

公开(公告)日：2012-07-12

申请号：US13425770

申请日：2012-03-21

申请人： Leonid M. Litvak ,  Aniket Saoji

发明人： Leonid M. Litvak ,  Aniket Saoji

IPC分类号： A61F11/04 ,  H04R25/00

CPC分类号： A61N1/36032 ,  A61N1/0541 ,  A61N1/36036

摘要： An exemplary method includes 1) applying a main current to a first electrode disposed within a patient and associated with a first pitch, 2) concurrently applying a compensation current to a second electrode disposed within the patient and associated with a second pitch during the application of the main current, the compensation current being out-of-phase with the main current, and 3) optimizing an amount of the compensation current to result in a target pitch being presented to the patient that is distanced from the first pitch in a pitch direction opposite a pitch direction of the second pitch in relation to the first pitch. Corresponding methods and systems are also disclosed.

摘要翻译： 一种示例性方法包括：1）将主电流施加到设置在患者体内并与第一间距相关联的第一电极; 2）在应用期间同时向布置在患者体内的第二电极施加补偿电流，并与第二电极相关联 主电流，补偿电流与主电流异相，以及3）优化补偿电流的量以导致目标音调被呈现给在间距方向上与第一音调间隔的患者 相对于第一间距与第二间距的俯仰方向相反。 还公开了相应的方法和系统。

公开(公告)号：US08209026B1

公开(公告)日：2012-06-26

申请号：US13217704

申请日：2011-08-25

申请人： Aniket Saoji ,  Leonid M. Litvak

发明人： Aniket Saoji ,  Leonid M. Litvak

IPC分类号： A61N1/08

CPC分类号： A61N1/36036

摘要： Methods of optimizing stimulation current applied to a cochlear implant patient include determining a plurality of narrowband spectral modulation detection thresholds for the patient and adjusting a stimulation current applied to the patient in accordance with the narrowband spectral modulation detection thresholds. Systems for optimizing stimulation current applied to a cochlear implant patient include an electrode array having a plurality of electrodes disposed thereon, an implantable cochlear stimulator coupled to the electrode array and configured to apply a stimulation current to one or more locations along a cochlea of a patient via one or more of the electrodes, and a fitting station communicatively coupled to the implantable cochlear stimulator. The fitting station is configured determine a plurality of narrowband spectral modulation detection thresholds and adjust the stimulation current in accordance with the narrowband spectral modulation detection thresholds.

摘要翻译： 优化施加到耳蜗植入患者的刺激电流的方法包括确定患者的多个窄带频谱调制检测阈值，并根据窄带频谱调制检测阈值调整施加到患者的刺激电流。 用于优化施加到耳蜗植入物患者的刺激电流的系统包括具有布置在其上的多个电极的电极阵列，耦合到电极阵列并被配置为将刺激电流施加到沿着患者的耳蜗的一个或多个位置的可植入耳蜗刺激器 通过一个或多个电极，以及通信地耦合到可植入耳蜗刺激器的装配台。 配置站配置确定多个窄带频谱调制检测阈值，并根据窄带频谱调制检测阈值调整刺激电流。