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公开(公告)号:US07846466B2
公开(公告)日:2010-12-07
申请号:US11149462
申请日:2005-06-09
申请人: Lonnie D. Shea , Lonnie L. Shea , Kevin Whittlesey , Yang Yang , Christopher Rives , Laura De LaPorte , Jae-Hyung Jang
发明人: Lonnie D. Shea , Lonnie L. Shea , Kevin Whittlesey , Yang Yang , Christopher Rives , Laura De LaPorte , Jae-Hyung Jang
CPC分类号: A61L27/56 , A61K38/18 , A61L27/18 , A61L27/54 , A61L2300/252 , A61L2300/258 , A61L2300/414 , A61L2300/602 , A61L2300/64 , A61L2430/32 , C08L67/06
摘要: The invention is directed to scaffolds containing porous polymer material prepared by a process of gas foaming/particulate leaching and a wet granulation step prior to gas foaming and particulate leaching, particularly having a characteristic interconnected pore structure, as well as sustained release of protein, DNA or cells, and to methods for using such porous polymer material for preparation of scaffolds, particularly for tissue engineering.
摘要翻译: 本发明涉及包含多孔聚合物材料的支架,其通过气体发泡/颗粒浸出的方法制备,并且在气体发泡和颗粒浸出之前进行湿法制粒步骤,特别是具有特征相互连通的孔结构,以及蛋白质,DNA的持续释放 或细胞,以及使用这种多孔聚合物材料制备支架的方法,特别是用于组织工程。