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    Process for optimizing milk production
    2.
    发明授权
    Process for optimizing milk production 失效
    优化牛奶生产的过程

    公开(公告)号：US06183786B2

    公开(公告)日：2001-02-06

    申请号：US09333095

    申请日：1999-06-15

    Applicant: Christopher D. Knight ,  Karen M. Koenig ,  Lyle M. Rode ,  Michael J. Vandenberg ,  Mercedes Vazquez-Anon

    Inventor： Christopher D. Knight ,  Karen M. Koenig ,  Lyle M. Rode ,  Michael J. Vandenberg ,  Mercedes Vazquez-Anon

    IPC: A23K116

    CPC classification number: A23K50/10 ,  A23K20/105 ,  A23K20/142 ,  Y10S426/807

    Abstract: A process for formulating a ruminant food ration in which the methionine needs of the ruminant are determined, a plurality of natural or synthetic feed ingredients and the nutrient composition of each of said ingredients are identified wherein one of said ingredients is 2-hydroxy-4-(methylthio)butanoic acid or a salt, amide or ester thereof, and a ration is formulated from the identified feed ingredients to meet the determined methionine needs of the ruminant which comprises one or more grains, a hydroxy analog of methionine, and optionally a bypass fat wherein (i) the hydroxy analog of methionine is selected from the group consisting of 2-hydroxy-4-(methylthio)butanoic acid and the salts, amides and esters thereof, (ii) the hydroxy analog of methionine is added separately from any bypass fat which is included in the ration, and (iii) the ration is formulated on the basis that at least 20% of the hydroxy analog of methionine is assumed to be available for absorption by the ruminant.

    Abstract translation: 确定其中反刍动物的甲硫氨酸需求的反刍动物食物比例的方法，确定多种天然或合成饲料成分以及每种所述成分的营养成分，其中所述成分之一是2-羟基-4- （甲硫基）丁酸或其盐，酰胺或酯，并且从所鉴定的进料成分配制比例，以满足反刍动物测定的甲硫氨酸需求，所述反刍动物包含一种或多种谷物，甲硫氨酸的羟基类似物和任选的旁路 脂肪，其中（i）甲硫氨酸的羟基类似物选自2-羟基-4-（甲硫基）丁酸及其盐，酰胺和酯，（ii）甲硫氨酸的羟基类似物与任何 包括在配给中的旁路脂肪，和（iii）配给是基于至少20％的甲硫氨酸的羟基类似物被假设可用于反刍动物吸收。

    Method of growing bacteria to deliver bioactive compounds to the intestine of ruminants
    3.
    发明申请
    Method of growing bacteria to deliver bioactive compounds to the intestine of ruminants 审中-公开
    生长细菌以将生物活性化合物递送至反刍动物肠道的方法

    公开(公告)号：US20080118472A1

    公开(公告)日：2008-05-22

    申请号：US11295853

    申请日：2005-12-06

    Applicant: Lyle M. Rode ,  C. James Newbold

    Inventor： Lyle M. Rode ,  C. James Newbold

    IPC: A61K35/74 ,  C12N1/21 ,  C12P13/08

    CPC classification number: C12Q1/04 ,  A23K10/18 ,  A23K20/142 ,  A23K50/10 ,  G01N2333/34

    Abstract: Methods for increasing the resistance to rumen inactivation of a cultured Gram positive bacteria strain useful for gastrointestinal delivery of bioactive compounds to ruminants, which includes the steps of growing a culture of the bacteria strain through at least one passage in a growth medium containing an amount of lysozyme effective to induce the growth of bacterial cell walls resistant to protozoal predation; and recovering the bacteria strain from the lysozyme-containing medium. Rumen-bypass feed supplements produced by the inventive method are also disclosed, as well as methods for supplementing the diet of a ruminant with the rumen bypass feed supplements and an in vitro method for evaluating the resistance of Gram positive bacteria strains to rumen inactivation in vivo.

    Abstract translation: 用于增加对用于向反刍动物胃肠道递送生物活性化合物的培养的革兰氏阳性菌菌株对瘤胃灭活的抗性的方法，其包括通过生长培养基中培养细菌菌株的培养物的步骤，所述生长培养基含有一定量的 有效诱导抗原生动物捕食的细菌细胞壁生长的溶菌酶; 并从含溶菌酶的培养基中回收细菌菌株。 还公开了通过本发明方法产生的瘤胃旁路饲料补充剂以及用瘤胃旁路饲料补充剂补充反刍动物饮食的方法和用于评估革兰氏阳性菌菌株对体内瘤胃失活的抗性的体外方法 。

    Process for optimizing milk production
    6.
    发明授权
    Process for optimizing milk production 失效
    优化牛奶生产的过程

    公开(公告)号：US06017563A

    公开(公告)日：2000-01-25

    申请号：US900414

    申请日：1997-07-25

    Applicant: Christopher D. Knight ,  Karen M. Koenig ,  Lyle M. Rode ,  Michael J. Vandenberg ,  Mercedes Vazquez-Anon

    Inventor： Christopher D. Knight ,  Karen M. Koenig ,  Lyle M. Rode ,  Michael J. Vandenberg ,  Mercedes Vazquez-Anon

    IPC: A23K1/16 ,  A23K1/18 ,  A23K1/00 ,  A01K43/00

    CPC classification number: A23K50/10 ,  A23K20/105 ,  A23K20/142 ,  Y10S426/807

    Abstract: A process for formulating a ruminant food ration in which the methionine needs of the ruminant are determined, a plurality of natural or synthetic feed ingredients and the nutrient composition of each of the ingredients are identified wherein one of the ingredients is 2-hydroxy-4-(methylthio)butanoic acid or a salt, amide or ester thereof, and a ration is formulated from the identified feed ingredients to meet the determined methionine needs of the ruminant which comprises one or more grains, a hydroxy analog of methionine, and optionally a bypass fat wherein (i) the hydroxy analog of methionine is selected from the group consisting of 2-hydroxy-4-(methylthio)butanoic acid and the salts, amides and esters thereof, (ii) the hydroxy analog of methionine is added separately from any bypass fat which is included in the ration, and (iii) the ration is formulated on the basis that at least 20% of the hydroxy analog of methionine is assumed to be available for absorption by the ruminant.

    Abstract translation: 确定反刍动物食物比例的方法，其中确定反刍动物的甲硫氨酸需求，鉴定出多种天然或合成饲料成分和每种成分的营养组合物，其中一种成分是2-羟基-4- （甲硫基）丁酸或其盐，酰胺或酯，并且从所鉴定的进料成分配制比例，以满足反刍动物测定的甲硫氨酸需求，所述反刍动物包含一种或多种谷物，甲硫氨酸的羟基类似物和任选的旁路 脂肪，其中（i）甲硫氨酸的羟基类似物选自2-羟基-4-（甲硫基）丁酸及其盐，酰胺和酯，（ii）甲硫氨酸的羟基类似物与任何 包括在配给中的旁路脂肪，和（iii）配给是基于至少20％的甲硫氨酸的羟基类似物被假设可用于反刍动物吸收。

    Process for optimizing milk production
    7.
    发明授权
    Process for optimizing milk production 失效

    公开(公告)号：US06319525B1

    公开(公告)日：2001-11-20

    申请号：US09697235

    申请日：2000-10-26

    Applicant: Christopher D. Knight ,  Karen M. Koenig ,  Lyle M. Rode ,  Michael J. Vandenberg ,  Mercedes Vazquez-Anon

    Inventor： Christopher D. Knight ,  Karen M. Koenig ,  Lyle M. Rode ,  Michael J. Vandenberg ,  Mercedes Vazquez-Anon

    IPC: A23K100

    CPC classification number: A23K50/10 ,  A23K20/105 ,  A23K20/142 ,  Y10S426/807

    Abstract: A process for formulating a ruminant food ration in which the methionine needs of the ruminant are determined, a plurality of natural or synthetic feed ingredients and the nutrient composition of each of said ingredients are identified wherein one of said ingredients is 2-hydroxy-4-(methylthio)butanoic acid or a salt, amide or ester thereof, and a ration is formulated from the identified feed ingredients to meet the determined methionine needs of the ruminant which comprises one or more grains, a hydroxy analog of methionine, and optionally a bypass fat wherein (i) the hydroxy analog of methionine is selected from the group consisting of 2-hydroxy-4-(methylthio)butanoic acid and the salts, amides and esters thereof, (ii) the hydroxy analog of methionine is added separately from any bypass fat which is included in the ration, and (iii) the ration is formulated on the basis that at least 20% of the hydroxy analog of methionine is assumed to be available for absorption by the ruminant.

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