-
公开(公告)号:US08765677B2
公开(公告)日:2014-07-01
申请号:US13497363
申请日:2010-09-21
申请人: Richard Lewis , David John Adams , Geza Berecki , Roger Drinkwater , Paul Francis Alewood , MacDonald James Christie
发明人: Richard Lewis , David John Adams , Geza Berecki , Roger Drinkwater , Paul Francis Alewood , MacDonald James Christie
IPC分类号: A61K38/16 , C07K14/00 , A61P35/00 , A61P9/12 , A61P29/00 , A61P1/00 , A61P13/00 , A61P25/18 , A61P25/04
CPC分类号: C07K14/43504 , A61K38/00
摘要: This invention relates to an isolated, synthetic or recombinant peptide, wherein the peptide comprises the sequence: C K G K G A Xaa1 C R Xaa2 Xaa3 Xaa4 Y Xaa5 C C Xaa6 G Xaa7 C R Xaa8 Xaa9 R C SEQ ID NO: 1 wherein Xaa1, Xaa3, Xaa4, Xaa6, Xaa7 and Xaa8 are independently selected from serine and threonine; Xaa2 is selected from arginine and lysine; Xaa5 is selected from aspartic acid and glutamic acid; and Xaa9 is selected from glycine, alanine, valine, leucine and isoleucine.
摘要翻译: 本发明涉及一种分离的,合成的或重组的肽,其中肽包含序列:CKGKGA Xaa1 CR Xaa2 Xaa3 Xaa4 Y Xaa5 CC Xaa6 G Xaa7 CR Xaa8 Xaa9 RC SEQ ID NO:1其中Xaa1,Xaa3,Xaa4,Xaa6,Xaa7 Xaa8独立地选自丝氨酸和苏氨酸; Xaa2选自精氨酸和赖氨酸; Xaa5选自天冬氨酸和谷氨酸; 并且Xaa9选自甘氨酸,丙氨酸,缬氨酸,亮氨酸和异亮氨酸。