专利检索 ap:"Macharla PRABHAKAR" 第 1 页

1.

发明申请
PROCESS FOR THE PREPARATION OF 5-[[[(2S)-2-AMINO-3-[4-(AMINOCARBONYL)-2,6-DIMETHYLPHENYL]-1-OXOPROPYL] [(1S)-1-(4-PHENYL-1H-IMIDAZOL-2-YL)ETHYL]AMINO] METHYL-2-METHOXYBENZOIC ACID AND ITS POLYMORPHS THEREOF 审中-公开

公开(公告)号：US20190177281A1

公开(公告)日：2019-06-13

申请号：US16099141

申请日：2017-05-02

申请人： Sromovasam THIRUMALAI RAJAN , Sajja ESWARAIAH , Sagyam RAJESHWAR REDDY , Macharla PRABHAKAR , Boge RAJESHAM , MSN LABORATORIES PRIVATE LIMITED

发明人： Srinivasan Thirumalai RAJAN , Eswaraiah SAJJA , Rajeshwar Reddy SAGYAM , Prabhakar MACHARLA , Rajesham BOGE

IPC分类号： C07D233/64

摘要： The present invention relates to an improved process for the preparation of 5-[[[(2S)-2-amino-3-[4-(aminocarbonyl)-2,6-dimethylphenyl]-1-oxopropyl][(1S)-1-(4-phenyl-1H-imidazol-2-yl)ethyl]amino]methyl]-2-methoxybenzoic acid compound of formula-1, and polymorphs thereof, the compound of formula-1 is further represented by the following structural formula: