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公开(公告)号:US20090012051A1
公开(公告)日:2009-01-08
申请号:US11908232
申请日:2006-03-15
申请人: Jun Sugishita , Yohei Yamazoe , Maho Nishikawahara , Daisuke Harada , Katsuya Kobayashi , Yoshikazu Tashiro
发明人: Jun Sugishita , Yohei Yamazoe , Maho Nishikawahara , Daisuke Harada , Katsuya Kobayashi , Yoshikazu Tashiro
IPC分类号: A61K31/443 , A61K31/56 , A61P17/00
CPC分类号: A61K9/0014 , A61K31/357 , A61K31/443 , A61K31/56 , A61K31/565 , A61K47/06 , A61K47/14 , A61K47/44 , A61K2300/00
摘要: The present invention provides an external preparation which comprises 7-[2-(3,5-dichloro-4-pyridyl)-1-oxoethyl]-4-methoxy-spiro[1,3-benzodioxol-2,1′-cyclopentane] represented by Formula (I) or a pharmaceutically acceptable salt thereof as an active ingredient, comprising 0.5 to 15% by mass of a solvent component in which the solubility of the active ingredient is 4 mg/mL or more, and the like.
摘要翻译: 本发明提供外部制剂,其包含7- [2-(3,5-二氯-4-吡啶基)-1-氧代乙基] -4-甲氧基 - 螺[1,3-苯并间二氧杂环戊烯-2,1'-环戊烷] 由式(I)表示的化合物或其药学上可接受的盐作为活性成分,含有0.5〜15质量%的活性成分的溶解性为4mg / mL以上的溶剂成分等。