GENE CLUSTER, GENE SEARCHING/IDENTIFICATION METHOD, AND APPARATUS FOR THE METHOD
    1.
    发明申请
    GENE CLUSTER, GENE SEARCHING/IDENTIFICATION METHOD, AND APPARATUS FOR THE METHOD 审中-公开
    基因组,基因组搜索/鉴定方法和方法的装置

    公开(公告)号:US20130237435A1

    公开(公告)日:2013-09-12

    申请号:US13825453

    申请日:2011-09-22

    IPC分类号: G06F19/18

    CPC分类号: G16B20/00 G16B25/00

    摘要: The present invention provides a method for searching for or identifying a useful gene logically, systematically, and efficiently in an extremely short time without largely relying on searcher's knowledge, experience, or the like and even without sequentially conducting gene disruption experiments as in conventional techniques of searching for a useful gene. The present invention also provides an apparatus for the method. Virtual gene clusters each comprising two or more genes are individually scored by summing the respective pieces of differential expression information (obtained using, for example, microarrays) of genomic genes on a per-cluster basis. On the basis of the obtained scores of the virtual gene clusters, a gene cluster containing a useful gene and the useful gene contained in the cluster are searched for.

    摘要翻译: 本发明提供了一种用于在非常短的时间内逻辑,系统和有效地搜索或鉴定有用基因的方法,而不需要大量依赖于搜索者的知识,经验等,并且甚至没有依次进行基因破坏实验,如常规技术 寻找有用的基因。 本发明还提供了一种用于该方法的装置。 通过在基于每个簇的基础上对基因组基因的差异表达信息(例如,微阵列获得)的各个片段进行求和来分别计算每个包含两个或更多个基因的虚拟基因簇。 在获得的虚拟基因簇得分的基础上,搜索包含有用基因的基因簇和簇中包含的有用基因。