公开(公告)号：US09149482B2

公开(公告)日：2015-10-06

申请号：US11579988

申请日：2004-05-10

申请人： Sanjay Wagh ,  Hidaytulla Aga ,  Makarand Avachat ,  Himadri Sen

发明人： Sanjay Wagh ,  Hidaytulla Aga ,  Makarand Avachat ,  Himadri Sen

IPC分类号： A61K9/20 ,  A61K31/545 ,  A61K31/546 ,  A61K9/00

CPC分类号： A61K31/546 ,  A61K9/0056

摘要： A chewable tablet comprising Cefixime having a mean particle size between 20μ and 120μ wherein the said composition demonstrates bioequivalence to a suspension of Cefixime trihydrate. The process of preparation of the chewable tablet comprises the steps of optionally micronizing Cefixime such that the mean particle size of the Cefixime particles is between 20μ and 120μ, blending with other excipients, roll compaction, milling to form granules, blending to form a secondary blend and compression of the secondary blend to form tablets.

摘要翻译： 一种咀嚼片，其包含平均粒径在20μ和120μ之间的头孢克肟，其中所述组合物显示与头孢克肟三水合物的悬浮液的生物等效性。 咀嚼片的制备方法包括以下步骤：任选地将头孢克肟微粉化，使得头孢克肟颗粒的平均粒径为20-120μ，与其它赋形剂混合，辊压，研磨形成颗粒，共混以形成二次共混物 并压制二次共混物以形成片剂。

公开(公告)号：US20190070167A1

公开(公告)日：2019-03-07

申请号：US15698135

申请日：2017-09-07

申请人： Imtiyaz Naikwadi ,  Vikram Karne ,  Prafulla Firodiya ,  Makarand Avachat ,  Sanjay C. Wagh

发明人： Imtiyaz Naikwadi ,  Vikram Karne ,  Prafulla Firodiya ,  Makarand Avachat ,  Sanjay C. Wagh

IPC分类号： A61K31/4709 ,  A61K47/02 ,  A61K9/20

摘要： The present invention provides a stable oral pharmaceutical composition comprising pitavastatin or a pharmaceutically acceptable salts thereof and at least one alkalizing agent selected from the group consisting of sodium hydroxide, sodium carbonate and sodium bicarbonate, and an aqueous solution or an aqueous dispersion of the pitavastatin containing preparation having a pH of more than 8 and 10 or less; and a method for producing the pitavastatin containing preparation.

公开(公告)号：US20110136921A1

公开(公告)日：2011-06-09

申请号：US12737663

申请日：2009-08-06

申请人： Nilesh Tanhaji Dumbre ,  Amelia Makarand Avachat ,  Nandu Deorkar ,  James Farina ,  Liliana Miinea

发明人： Nilesh Tanhaji Dumbre ,  Amelia Makarand Avachat ,  Nandu Deorkar ,  James Farina ,  Liliana Miinea

IPC分类号： A61K47/26 ,  B29B9/12 ,  B29B9/10

CPC分类号： A61K9/1623 ,  A61K9/1652 ,  A61K9/2018 ,  A61K9/205 ,  A61K9/2054 ,  A61K31/09 ,  A61K31/135 ,  A61K31/137 ,  A61K31/167 ,  A61K31/196

摘要： A sustained release composition comprising spray dried particles of at least one polysaccharide gum and at least one polyhydric sugar alcohol, as well as methods of making the sustained released composition are provided. A sustained release pharmaceutical solid dosage form, and a method of making the solid dosage form by compression are also provided.

摘要翻译： 提供包含至少一种多糖胶和至少一种多羟基糖醇的喷雾干燥颗粒的持续释放组合物，以及制备持续释放的组合物的方法。 还提供了缓释药物固体剂型，以及通过压缩制备固体剂型的方法。

公开(公告)号：US20070286901A1

公开(公告)日：2007-12-13

申请号：US11579988

申请日：2004-05-10

申请人： Sanjay Wagh ,  Hidaytulla Aga ,  Makarand Avachat ,  Himadri Sen

发明人： Sanjay Wagh ,  Hidaytulla Aga ,  Makarand Avachat ,  Himadri Sen

IPC分类号： A61K9/20 ,  A61K31/545 ,  A61P31/04

CPC分类号： A61K31/546 ,  A61K9/0056

摘要： A chewable tablet comprising Cefixime having a mean particle size between 20 μ and 120 μ wherein the said composition demonstrates bioequivalence to a suspension of Cefixime trihydrate. The process of preparation of the chewable tablet comprises the steps of optionally micronizing Cefixime such that the mean particle size of the Cefixime particles is between 20 μ and 120 μ, blending with other excipients, roll compaction, milling to form granules, blending to form a secondary blend and compression of the secondary blend to form tablets.

摘要翻译： 一种包含Cefixime的咀嚼片，其平均粒度为20-120微米，其中所述组合物显示出Cefixime三水合物的悬浮液的生物等效性。 咀嚼片的制备方法包括以下步骤：任选地将头孢克肟微粉化，使得头孢克肟颗粒的平均粒度为20-120微米，与其它赋形剂混合，辊压，研磨形成颗粒，混合形成 二次混合和二次混合物的压缩以形成片剂。