COLON CLEANSING COMPOSITIONS AND METHODS
    1.
    发明申请

    公开(公告)号:US20100297263A1

    公开(公告)日:2010-11-25

    申请号:US12852473

    申请日:2010-08-07

    Abstract: A composition comprising, per litre of aqueous solution, from 30 to 350 g polyethylene glycol, from 3 to 20 g of an ascorbic acid component selected form the group consisting of ascorbic acid, a salt of ascorbic acid, or a mixture thereof, an alkali metal or alkaline earth metal sulphate, preferably from 1 to 15 g thereof, and optionally one or more electrolytes selected from sodium chloride, potassium chloride, and sodium hydrogen carbonate, and preferably also comprising flavourings, is effective in cleansing the gut in preparation for a endoscopy, especially colonoscopy. It is safer than conventional sodium phosphate-based gut cleansing compositions, and hence can be used for patients who would be at risk with sodium phosphate-based compositions, and is better tolerated than conventional PEG-based compositions, leading to better patient compliance and enabling effective out-patient use.

    COLON CLEANSING COMPOSITIONS AND METHODS
    4.
    发明申请
    COLON CLEANSING COMPOSITIONS AND METHODS 审中-公开
    COLOR CLEANSING组合物和方法

    公开(公告)号:US20100189815A1

    公开(公告)日:2010-07-29

    申请号:US12754161

    申请日:2010-04-05

    Abstract: A composition comprising, per litre of aqueous solution, from 30 to 350 g polyethylene glycol, from 3 to 20 g of an ascorbic acid component selected from the group consisting of ascorbic acid, a salt of ascorbic acid, or a mixture thereof, an alkali metal or alkaline earth metal sulphate, preferably from 1 to 15 g thereof, and optionally one or more electrolytes selected from sodium chloride, potassium chloride, and sodium hydrogen carbonate, and preferably also comprising flavourings, is effective in cleansing the gut in preparation for a endoscopy, especially colonoscopy. It is safer than conventional sodium phosphate-based gut cleansing compositions, and hence can be used for patients who would be at risk with sodium phosphate-based compositions, and is better tolerated than conventional PEG-based compositions, leading to better patient compliance and enabling effective out-patient use.

    Abstract translation: 一种组合物,其包含每升水溶液30至350g聚乙二醇,3至20g选自抗坏血酸,抗坏血酸盐或其混合物的抗坏血酸组分,碱 金属或碱土金属硫酸盐,优选其1至15g,以及任选的一种或多种选自氯化钠,氯化钾和碳酸氢钠的电解质,并且优选还包含调味剂,在清洁肠道中有效,以制备 内镜检查,特别是结肠镜检查。 它比常规磷酸钠基肠清洁组合物更安全,因此可用于使用基于磷酸钠的组合物处于危险中的患者,并且比常规的基于PEG的组合物更耐受,导致更好的患者依从性和使能 有效的门诊使用。

    Colon cleansing compositions
    5.
    发明授权
    Colon cleansing compositions 有权
    结肠清洁组合物

    公开(公告)号:US07658914B2

    公开(公告)日:2010-02-09

    申请号:US11636105

    申请日:2006-12-08

    Abstract: A composition comprising, per liter of aqueous solution, from 30 to 350 g polyethylene glycol, from 3 to 20 g of an ascorbic acid component selected form the group consisting of ascorbic acid, a salt of ascorbic acid, or a mixture thereof, an alkali metal or alkaline earth metal sulphate, preferably from 1 to 15 g thereof, and optionally one or more electrolytes selected from sodium chloride, potassium chloride, and sodium hydrogen carbonate, and preferably also comprising flavorings, is effective in cleansing the gut in preparation for a endoscopy, especially colonoscopy. It is safer than conventional sodium phosphate-based gut cleansing compositions, and hence can be used for patients who would be at risk with sodium phosphate-based compositions, and is better tolerated than conventional PEG-based compositions, leading to better patient compliance and enabling effective out-patient use.

    Abstract translation: 一种组合物,其包含每升水溶液30至350g聚乙二醇,3至20g抗坏血酸组分,选自抗坏血酸,抗坏血酸盐或其混合物,碱 金属或碱土金属硫酸盐,优选其1至15g,以及任选的一种或多种选自氯化钠,氯化钾和碳酸氢钠的电解质,并且优选还包含调味剂,在清洁肠道中有效,以制备 内镜检查,特别是结肠镜检查。 它比常规磷酸钠基肠清洁组合物更安全,因此可用于使用基于磷酸钠的组合物处于危险中的患者,并且比常规的基于PEG的组合物更耐受,导致更好的患者依从性和使能 有效的门诊使用。

    COLON CLEANSING COMPOSITIONS AND METHODS
    6.
    发明申请
    COLON CLEANSING COMPOSITIONS AND METHODS 审中-公开
    COLOR CLEANSING组合物和方法

    公开(公告)号:US20100196513A1

    公开(公告)日:2010-08-05

    申请号:US12753949

    申请日:2010-04-05

    Abstract: A composition comprising, per litre of aqueous solution, from 30 to 350 g polyethylene glycol, from 3 to 20 g of an ascorbic acid component selected form the group consisting of ascorbic acid, a salt of ascorbic acid, or a mixture thereof, an alkali metal or alkaline earth metal sulphate, preferably from 1 to 15 g thereof, and optionally one or more electrolytes selected from sodium chloride, potassium chloride, and sodium hydrogen carbonate, and preferably also comprising flavourings, is effective in cleansing the gut in preparation for a endoscopy, especially colonoscopy. It is safer than conventional sodium phosphate-based gut cleansing compositions, and hence can be used for patients who would be at risk with sodium phosphate-based compositions, and is better tolerated than conventional PEG-based compositions, leading to better patient compliance and enabling effective out-patient use.

    Abstract translation: 一种组合物,其包含每升水溶液30至350g聚乙二醇,3至20g抗坏血酸组分,选自抗坏血酸,抗坏血酸盐或其混合物,碱 金属或碱土金属硫酸盐,优选其1至15g,以及任选的一种或多种选自氯化钠,氯化钾和碳酸氢钠的电解质,并且优选还包含调味剂,在清洁肠道中有效,以制备 内镜检查,特别是结肠镜检查。 它比常规磷酸钠基肠清洁组合物更安全,因此可用于使用基于磷酸钠的组合物处于危险中的患者,并且比常规的基于PEG的组合物更耐受,导致更好的患者依从性和使能 有效的门诊使用。

    COLON CLEANSING COMPOSITIONS AND METHODS
    7.
    发明申请

    公开(公告)号:US20100086624A1

    公开(公告)日:2010-04-08

    申请号:US12633663

    申请日:2009-12-08

    Abstract: A composition comprising, per litre of aqueous solution, from 30 to 350 g polyethylene glycol, from 3 to 20 g of an ascorbic acid component selected form the group consisting of ascorbic acid, a salt of ascorbic acid, or a mixture thereof, an alkali metal or alkaline earth metal sulphate, preferably from 1 to 15 g thereof, and optionally one or more electrolytes selected from sodium chloride, potassium chloride, and sodium hydrogen carbonate, and preferably also comprising flavourings, is effective in cleansing the gut in preparation for a endoscopy, especially colonoscopy. It is safer than conventional sodium phosphate-based gut cleansing compositions, and hence can be used for patients who would be at risk with sodium phosphate-based compositions, and is better tolerated than conventional PEG-based compositions, leading to better patient compliance and enabling effective out-patient use.

    COLONOSCOPY - PREPARATION
    8.
    发明申请
    COLONOSCOPY - PREPARATION 有权
    COLONOSCOPY - 准备

    公开(公告)号:US20140010895A1

    公开(公告)日:2014-01-09

    申请号:US14004604

    申请日:2012-03-09

    Abstract: The invention provides a colon cleansing solution comprising: a) 300 to 2000 mmol per litre ascorbate anion provided by ascorbic acid, one or more salts of ascorbic acid, or a mixture thereof; and b) 10 to 200 g per litre polyethylene glycol. The invention also provides methods and kits associated with, or making use of the solutions. The invention also provides a method of cleansing the colon of a subject comprising: — administering to the subject an effective amount of a first cleansing solution; and then after a time interval-administering to the subject an effective amount of a second cleansing solution, where in the two cleansing solutions are as described in the specification.

    Abstract translation: 本发明提供一种结肠清洗溶液,其包含:a)每升抗坏血酸阴离子300至2000mmol,由抗坏血酸,一种或多种抗坏血酸盐或其混合物提供; 和b)10至200g /升聚乙二醇。 本发明还提供与溶液相关联或利用该溶液的方法和试剂盒。 本发明还提供一种清洁受试者结肠的方法,包括: - 向受试者施用有效量的第一清洁溶液; 然后经过一段时间间隔 - 向受试者施用有效量的第二清洁溶液,其中两种清洁溶液如说明书中所述。

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