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公开(公告)号：US5691309A
公开(公告)日：1997-11-25
申请号：US383650
申请日：1995-02-06
申请人： Margret B. Basinski , Richard D. DiMarchi , David B. Flora , William F. Heath, Jr. , James A. Hoffmann , Brigitte E. Schoner , James E. Shields , David L. Smiley
发明人： Margret B. Basinski , Richard D. DiMarchi , David B. Flora , William F. Heath, Jr. , James A. Hoffmann , Brigitte E. Schoner , James E. Shields , David L. Smiley
IPC分类号： A61K38/00 , C07K14/575 , C07K1/00 , C07K5/00 , C07K7/00
CPC分类号： C07K14/5759 , A61K38/00
摘要： The present invention provides anti-obesity proteins, which when administered to a patient regulate fat tissue. Accordingly, such agents allow patients to overcome their obesity handicap and live normal lives with much reduced risk for type II diabetes, cardiovascular disease and cancer.
摘要翻译： 本发明提供了抗肥胖蛋白质，其在施用于患者时调节脂肪组织。 因此，这样的药物允许患者克服其肥胖障碍和生活正常生活，其中II型糖尿病，心血管疾病和癌症风险大大降低。
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公开(公告)号：US5552523A
公开(公告)日：1996-09-03
申请号：US384183
申请日：1995-02-06
IPC分类号： A61K38/00 , C07K14/575 , C07K7/00 , C07K7/10
CPC分类号： C07K14/5759 , A61K38/00
摘要： The present invention provides anti-obesity proteins, which when administered to a patient regulate fat tissue. Accordingly, such agents allow patients to overcome their obesity handicap and live normal lives with much reduced risk for type II diabetes, cardiovascular disease and cancer.
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公开(公告)号：US06395509B1
公开(公告)日：2002-05-28
申请号：US08452228
申请日：1995-05-26
IPC分类号： C12P2106
CPC分类号： C07K14/5759 , A61K38/00
摘要： The invention includes isolated nucleic acid molecules encoding a Rhesus ob gene product that regulates obesity in mammals. A preferred embodiment consisting of a native DNA sequence is disclosed, as are vectors and methods for expressing the Rhesus ob gene product.
摘要翻译： 本发明包括编码调节哺乳动物肥胖的恒河猴ob基因产物的分离的核酸分子。 公开了由天然DNA序列组成的优选实施方案，以及用于表达恒河猴基因产物的载体和方法。
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公开(公告)号：US5559208A
公开(公告)日：1996-09-24
申请号：US383639
申请日：1995-02-06
IPC分类号： A61K38/00 , C07K14/575 , A61K35/00 , C07K7/10
CPC分类号： C07K14/5759 , A61K38/00
摘要： The present invention provides anti-obesity proteins, which when administered to a patient regulate fat tissue. Accordingly, such agents allow patients to overcome their obesity handicap and live normal lives with much reduced risk for type II diabetes, cardiovascular disease and cancer.
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公开(公告)号：US5594104A
公开(公告)日：1997-01-14
申请号：US384492
申请日：1995-02-06
申请人： Margret B. Basinski , Richard D. DiMarchi , David B. Flora , William F. Heath, Jr. , James A. Hoffmann , Brigitte E. Schoner , James E. Shields , David L. Smiley
发明人： Margret B. Basinski , Richard D. DiMarchi , David B. Flora , William F. Heath, Jr. , James A. Hoffmann , Brigitte E. Schoner , James E. Shields , David L. Smiley
IPC分类号： A61K38/00 , C07K14/575 , C07K7/00 , C07K7/10
CPC分类号： C07K14/5759 , A61K38/00
摘要： The present invention provides anti-obesity proteins, which when administered to a patient regulate fat tissue. Accordingly, such agents allow patients to overcome their obesity handicap and live normal lives with much reduced risk for type II diabetes, cardiovascular disease and cancer.
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公开(公告)号：US5552524A
公开(公告)日：1996-09-03
申请号：US384292
申请日：1995-02-06
IPC分类号： A61K38/00 , C07K14/575 , C07K7/00 , C07K7/10
CPC分类号： C07K14/5759 , A61K38/00 , C07K2319/00
摘要： The present invention provides anti-obesity proteins, which when administered to a patient regulate fat tissue. Accordingly, such agents allow patients to overcome their obesity handicap and live normal lives with much reduced risk for type II diabetes, cardiovascular disease and cancer.
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公开(公告)号：US5605886A
公开(公告)日：1997-02-25
申请号：US442916
申请日：1995-05-17
申请人： Margret B. Basinski , Richard D. DiMarchi , David B. Flora , William F. Heath, Jr. , James A. Hoffmann , Brigitte E. Schoner , James E. Shields , David L. Smiley
发明人： Margret B. Basinski , Richard D. DiMarchi , David B. Flora , William F. Heath, Jr. , James A. Hoffmann , Brigitte E. Schoner , James E. Shields , David L. Smiley
IPC分类号： C12N15/09 , A61K38/00 , A61P3/00 , A61P3/08 , A61P3/10 , C07K14/47 , C07K14/575 , C12P21/02 , C12R1/19
CPC分类号： C07K14/5759 , A61K38/00
摘要： The present invention provides anti-obesity proteins, which when administered to a patient regulate fat tissue. Accordingly, such agents allow patients to overcome their obesity handicap and live normal lives with much reduced risk for type II diabetes, cardiovascular disease and cancer.
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公开(公告)号：US5569744A
公开(公告)日：1996-10-29
申请号：US383632
申请日：1995-02-06
申请人： Margret B. Basinski , Richard D. DiMarchi , David B. Flora , William F. Heath, Jr. , James A. Hoffmann , Brigitte E. Schoner , James E. Shields , David L. Smiley
发明人： Margret B. Basinski , Richard D. DiMarchi , David B. Flora , William F. Heath, Jr. , James A. Hoffmann , Brigitte E. Schoner , James E. Shields , David L. Smiley
IPC分类号： A61K38/00 , C07K14/575 , C07K14/00
CPC分类号： C07K14/5759 , A61K38/00
摘要： The present invention provides anti-obesity proteins, which when administered to a patient regulate fat tissue. Accordingly, such agents allow patients to overcome their obesity handicap and live normal lives with much reduced risk for type II diabetes, cardiovascular disease and cancer.
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公开(公告)号：US5554727A
公开(公告)日：1996-09-10
申请号：US383631
申请日：1995-02-06
IPC分类号： A61K38/00 , C07K14/575 , C07K7/00 , C07K7/10
CPC分类号： C07K14/5759 , A61K38/00
摘要： The present invention provides anti-obesity proteins, which when administered to a patient regulate fat tissue. Accordingly, such agents allow patients to overcome their obesity handicap and live normal lives with much reduced risk for type II diabetes, cardiovascular disease and cancer.
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公开(公告)号：US5851995A
公开(公告)日：1998-12-22
申请号：US905694
申请日：1997-08-04
申请人： Margret B. Basinski , Richard D. DiMarchi , David B. Flora , William F. Heath, Jr. , James A. Hoffmann , Brigitte E. Schoner , James E. Shields , David L. Smiley
发明人： Margret B. Basinski , Richard D. DiMarchi , David B. Flora , William F. Heath, Jr. , James A. Hoffmann , Brigitte E. Schoner , James E. Shields , David L. Smiley
IPC分类号： C12N15/09 , A61K38/00 , A61P3/00 , A61P3/08 , A61P3/10 , C07K14/47 , C07K14/575 , C12P21/02 , C12R1/19
CPC分类号： C07K14/5759 , A61K38/00
摘要： The present invention provides anti-obesity proteins, which when administered to a patient regulate fat tissue. Accordingly, such agents allow patients to overcome their obesity handicap and live normal lives with much reduced risk for type II diabetes, cardiovascular disease and cancer.
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