公开(公告)号：US08436002B2

公开(公告)日：2013-05-07

申请号：US13391895

申请日：2010-10-20

Applicant: Douglas Wade Beight ,  Timothy Paul Burkholder ,  Joshua Ryan Clayton ,  MariJean Eggen ,  Kenneth James Henry, Jr. ,  Deidre Michelle Johns ,  Saravanan Parthasarathy ,  Huaxing Pei ,  Mark Edward Rempala ,  Jason Scott Sawyer

Inventor： Douglas Wade Beight ,  Timothy Paul Burkholder ,  Joshua Ryan Clayton ,  MariJean Eggen ,  Kenneth James Henry, Jr. ,  Deidre Michelle Johns ,  Saravanan Parthasarathy ,  Huaxing Pei ,  Mark Edward Rempala ,  Jason Scott Sawyer

IPC: A01N43/54 ,  A01N43/90 ,  A01N43/42 ,  A01N43/40 ,  A61K31/517 ,  A61K31/519 ,  A61K31/44 ,  A61K31/445

CPC classification number: C07D471/04 ,  A61K31/519 ,  C07D487/04

Abstract: The present invention provides AKT inhibitors of the formula: Formula I The present invention also provides pharmaceutical compositions comprising compounds of Formula I, uses of compounds of Formula I and method of using compounds of Formula I.

Abstract translation: 本发明提供下式的AKT抑制剂：式I本发明还提供包含式I化合物的药物组合物，式I化合物的用途和使用式I化合物的方法。

公开(公告)号：US20120149684A1

公开(公告)日：2012-06-14

申请号：US13391895

申请日：2010-10-20

Applicant: Douglas Wade Beight ,  Timothy Paul Burkholder ,  Joshua Ryan Clayton ,  MariJean Eggen ,  Kenneth James Henry, JR. ,  Deidre Michelle Johns ,  Saravanan Parthasarathy ,  Huaxing Pei ,  Mark Edward Rempala ,  Jason Scott Sawyer

Inventor： Douglas Wade Beight ,  Timothy Paul Burkholder ,  Joshua Ryan Clayton ,  MariJean Eggen ,  Kenneth James Henry, JR. ,  Deidre Michelle Johns ,  Saravanan Parthasarathy ,  Huaxing Pei ,  Mark Edward Rempala ,  Jason Scott Sawyer

IPC: A61K31/519 ,  C07D487/04 ,  A61P35/00 ,  C07D471/04

CPC classification number: C07D471/04 ,  A61K31/519 ,  C07D487/04

Abstract: The present invention provides AKT inhibitors of the formula: Formula I The present invention also provides pharmaceutical compositions comprising compounds of Formula I, uses of compounds of Formula I and method of using compounds of Formula I.

Abstract translation: 本发明提供下式的AKT抑制剂：式I本发明还提供包含式I化合物的药物组合物，式I化合物的用途和使用式I化合物的方法。

公开(公告)号：US20050049245A1

公开(公告)日：2005-03-03

申请号：US10649208

申请日：2003-08-27

Applicant: Mark Schnute ,  Michele Cudahy ,  MariJean Eggen ,  David Anderson ,  Thomas Judge ,  Euibong Kim ,  Sarah Collier

Inventor： Mark Schnute ,  Michele Cudahy ,  MariJean Eggen ,  David Anderson ,  Thomas Judge ,  Euibong Kim ,  Sarah Collier

IPC: A61P31/12 ,  A61P31/18 ,  C07D495/04 ,  C07D498/02 ,  A61K31/4743 ,  A61K31/496 ,  A61K31/5377 ,  A61K31/541

CPC classification number: C07D495/04

Abstract: The present invention provides a compound of formula as described herein, which are useful as antiviral agents, in particular, as agents against viruses of the herpes family.

Abstract translation: 本发明提供了本文所述的式的化合物，其可用作抗病毒剂，特别是作为抗疱疹家族病毒的药剂。