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公开(公告)号：US09242971B2
公开(公告)日：2016-01-26
申请号：US14630624
申请日：2015-02-24
申请人： Christina Capacci-Daniel , Marilyn Delacruz , Baoqing Gong , Akash Jain , Yansong Lu , Lijun Zhang
发明人： Christina Capacci-Daniel , Marilyn Delacruz , Baoqing Gong , Akash Jain , Yansong Lu , Lijun Zhang
IPC分类号： C07D413/00 , C07D413/12 , A61K31/4439 , A61K45/06
CPC分类号： C07D413/12 , A61K31/4439 , A61K45/06
摘要： The present invention relates to novel crystalline forms of salts of 2-((1R,4R)-4-(4-(5-(benzo[d]oxazol-2-ylamino)pyridin-2-yl)phenyl)cyclohexyl)acetic acid and their use in the treatment or prevention of a condition or a disorder associated with DGAT1 activity in animals, particularly humans.
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2.发明授权公开(公告)号：US08987459B2
公开(公告)日：2015-03-24
申请号：US14152282
申请日：2014-01-10
申请人： Christina Capacci-Daniel , Marilyn DeLaCruz , Baoqing Gong , Akash Jain , Yansong Lu , Lijun Zhang
发明人： Christina Capacci-Daniel , Marilyn DeLaCruz , Baoqing Gong , Akash Jain , Yansong Lu , Lijun Zhang
IPC分类号： C07D413/00 , C07D413/12 , A61K31/4439 , A61K45/06
CPC分类号： C07D413/12 , A61K31/4439 , A61K45/06
摘要： The present invention relates to novel crystalline forms of salts of 2-((1R,4R)-4-(4-(5-(benzo[d]oxazol-2-ylamino)pyridin-2-yl)phenyl)cyclohexyl)acetic acid and their use in the treatment or prevention of a condition or a disorder associated with DGAT1 activity in animals, particularly humans.
摘要翻译： 本发明涉及2 - （（1R，4R）-4-（4-（5-（苯并[d]恶唑-2-基氨基）吡啶-2-基）苯基）环己基）乙酸的新型盐形式 酸及其用于治疗或预防与动物，特别是人类中DGAT1活性相关的病症或病症。
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3.发明申请COMPOUNDS FOR THE TREATMENT OF CONDITIONS ASSOCIATED WITH DGAT1 ACTIVITY 审中-公开用于处理与DGAT1活性相关的条件的化合物公开(公告)号：US20150166522A1
公开(公告)日：2015-06-18
申请号：US14630624
申请日：2015-02-24
申请人： Christina CAPACCI-DANIEL , Marilyn DELACRUZ , Baoqing GONG , Akash JAIN , Yansong LU , Lijun ZHANG
发明人： Christina CAPACCI-DANIEL , Marilyn DELACRUZ , Baoqing GONG , Akash JAIN , Yansong LU , Lijun ZHANG
IPC分类号： C07D413/12 , A61K31/4439
CPC分类号： C07D413/12 , A61K31/4439 , A61K45/06
摘要： The present invention relates to novel crystalline forms of salts of 2-((1R,4R)-4-(4-(5-(benzo[d]oxazol-2-ylamino)pyridin-2-yl)phenyl)cyclohexyl)acetic acid and their use in the treatment or prevention of a condition or a disorder associated with DGAT1 activity in animals, particularly humans.
摘要翻译： 本发明涉及2 - （（1R，4R）-4-（4-（5-（苯并[d]恶唑-2-基氨基）吡啶-2-基）苯基）环己基）乙酸 酸及其用于治疗或预防与动物，特别是人类中DGAT1活性相关的病症或病症。
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4.发明申请公开(公告)号：US20140200246A1
公开(公告)日：2014-07-17
申请号：US14152282
申请日：2014-01-10
申请人： Christina CAPACCI-DANIEL , Marilyn DELACRUZ , Baoqing GONG , Akash JAIN , Yansong LU , Lijun ZHANG
发明人： Christina CAPACCI-DANIEL , Marilyn DELACRUZ , Baoqing GONG , Akash JAIN , Yansong LU , Lijun ZHANG
IPC分类号： C07D413/12 , A61K45/06 , A61K31/4439
CPC分类号： C07D413/12 , A61K31/4439 , A61K45/06
摘要： The present invention relates to novel crystalline forms of salts of 2-((1R,4R)-4-(4-(5-(benzo[d]oxazol-2-ylamino)pyridin-2-yl)phenyl)cyclohexyl)acetic acid and their use in the treatment or prevention of a condition or a disorder associated with DGAT1 activity in animals, particularly humans.
摘要翻译： 本发明涉及2 - （（1R，4R）-4-（4-（5-（苯并[d]恶唑-2-基氨基）吡啶-2-基）苯基）环己基）乙酸 酸及其用于治疗或预防与动物，特别是人类中DGAT1活性相关的病症或病症。
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