公开(公告)号：US20060223189A1

公开(公告)日：2006-10-05

申请号：US10551032

申请日：2003-03-28

Applicant: Tetsuro Kawanishi ,  Mathew Romey ,  Mark Holody ,  Peter Zhu ,  Seiji Shinkai

Inventor： Tetsuro Kawanishi ,  Mathew Romey ,  Mark Holody ,  Peter Zhu ,  Seiji Shinkai

IPC: G01N33/00 ,  C07F5/02

CPC classification number: C07F5/025

Abstract: The present invention provides solid-phase saccharide dyes. The dyes are bisboronic acids covalently bonded to a solid substrate. The dyes selectively conjugate with saccharides, particularly glucose, and register a signal. The signal is proportional to the quantity of saccharide. Thus, the dyes of the present invention are useful for measuring and monitoring saccharide levels, particularly in biological fluids such as blood.

Abstract translation: 本发明提供固相糖染料。 染料是共价键合到固体基质上的双硼酸。 染料选择性地与糖结合，特别是葡萄糖，并记录信号。 信号与糖的数量成正比。 因此，本发明的染料可用于测量和监测糖水平，特别是在生物液体如血液中。