公开(公告)号：US20120095524A1

公开(公告)日：2012-04-19

申请号：US13381586

申请日：2010-06-29

Applicant: Timothy Scott Nelson ,  Mark James Cook ,  Anthony Neville Burkitt

Inventor： Timothy Scott Nelson ,  Mark James Cook ,  Anthony Neville Burkitt

IPC: A61N1/36

CPC classification number: A61N1/36082

Abstract: The present invention provides a method for counteracting seizure events in a mammalian brain, the method comprising applying an electrical stimulus to the brain, the electrical stimulus being pulsatile and comprising pulses forming a pulse train. In order to effectively “desynchronize” the neural activity patterns in the brain, the pulse train can be at a frequency greater than substantially 300 Hz and at a duty cycle greater than substantially 20%, the pulse train can have an inconstant inter pulse interval such that the pulse rate is not constant throughout the pulse train, and the pulses can have a pulse width greater than substantially 300 μsec. Apparatus for carrying out the method is also described.

Abstract translation: 本发明提供了一种用于抵消哺乳动物脑中的发作事件的方法，所述方法包括对脑进行电刺激，电刺激是脉动的并且包括形成脉冲序列的脉冲。 为了有效地“同步”大脑中的神经活动模式，脉冲串可以处于大于基本上为300Hz的频率，并且在大于大致20％的占空比下，脉冲串可以具有不均匀的脉冲间隔 在整个脉冲串中脉冲频率不是恒定的，并且脉冲可以具有大于基本上300μsec的脉冲宽度。 还描述了用于执行该方法的装置。