USE OF CD44V6 IN THE TREATMENT OF OPHTHALMIC DISEASES
    1.
    发明申请
    USE OF CD44V6 IN THE TREATMENT OF OPHTHALMIC DISEASES 审中-公开
    CD44V6在治疗眼底疾病中的应用

    公开(公告)号:US20120115794A1

    公开(公告)日:2012-05-10

    申请号:US13378574

    申请日:2010-06-11

    CPC分类号: A61K38/08 A61K38/177

    摘要: The present invention relates to the use of peptide compounds for the prevention and/or treatment of ophthalmic diseases. In particular, the present invention relates to a peptide compound comprising an amino acid sequence displayed by amino acids 7 to 11 of SEQ ID NO: 2 (KEQWFGNRWHEGYR) or of SEQ ID NO: 1 (KEKWFENEWQGKNP), or a functionally active derivative thereof, or a pharmaceutically acceptable salt thereof, for use in the prevention and/or treatmend of an ophthalmic disease in an individual. While SEQ ID NO: 2 is a part of the human CD44v6, SEQ ID NO: 1 is a part of the rat CD44v6.

    摘要翻译: 本发明涉及肽化合物在预防和/或治疗眼科疾病中的应用。 特别地,本发明涉及包含由SEQ ID NO:2(KEQWFGNRWHEGYR)或SEQ ID NO:1(KEKWFENEWQGKNP)的氨基酸7至11显示的氨基酸序列或其功能活性衍生物的肽化合物, 或其药学上可接受的盐,用于预防和/或治疗个体眼科疾病。 虽然SEQ ID NO:2是人CD44v6的一部分,但是SEQ ID NO:1是大鼠CD44v6的一部分。