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公开(公告)号:US07259290B1
公开(公告)日:2007-08-21
申请号:US10533796
申请日:2003-11-06
IPC分类号: C12N15/00 , G01N33/00 , A01K67/033
CPC分类号: C07K14/7155 , A01K67/0271 , A01K67/0276 , A01K2217/075 , A01K2227/105 , A01K2267/0331 , A01K2267/0381 , C12N15/8509
摘要: Production and utilization of model mouse, in which human hematopoietic tumor cells can be grown, expressing symptom of human hematopoietic tumor, and can be used in the screening of anticancer drugs for human hematopoietic tumor.The invention provides a new method to produce model mouse for human hematopoietic tumor, including engraftment of human hematopoietic tumor cells into NOG (NOD/Shi-scid, IL-2Rγ KO) mice.
摘要翻译: 模型小鼠的生产和利用,其中可以生长人类造血肿瘤细胞,表达人造血肿瘤的症状,并且可用于筛选用于人类造血肿瘤的抗癌药物。 本发明提供了一种新的人造血瘤模型小鼠的方法,包括将人造血肿瘤细胞植入NOG(NOD / Shi-scid,IL-2Rgamma KO)小鼠。