公开(公告)号：US06447790B1

公开(公告)日：2002-09-10

申请号：US09550334

申请日：2000-04-14

申请人： Hiroji Ishii ,  Masako Koyama ,  Tomomichi Ichikawa ,  Toshihiko Funakubo

发明人： Hiroji Ishii ,  Masako Koyama ,  Tomomichi Ichikawa ,  Toshihiko Funakubo

IPC分类号： A61K700

CPC分类号： A61Q19/00 ,  A61K8/44 ,  A61K8/63 ,  A61Q5/00 ,  A61Q5/12

摘要： Herein is disclosed an oily material composition comprising, as effective components, both a specific alkyl or alkenyl ester of an N-long chain acyl neutral amino acid and a specific sterol ester of an N-long chain acyl neutral amino acid, or further an amphipathic substance in addition to the said two kinds of esters, which composition has both good moisturizing property and good moisture-permeating property, as well as good water-incorporating property and good emulsification stability, and shows a good feel on use (i.e., non-stickiness, good compatibility, no heavy touch and good spreadability), and shows, when incorporated in a cosmetic composition or a dermal external agent composition, an advantage of giving moisturizing property and moisture-permeating property as well as emulsification stability thereto and of giving a good feel on use.

摘要翻译： 本文公开了一种油性材料组合物，其包含作为有效成分的N-长链酰基中性氨基酸的特定烷基或烯基酯和N-长链酰基中性氨基酸的特定甾醇酯或另外两亲性 除了所述两种酯之外，该组合物具有良好的保湿性和良好的透湿性，并且具有良好的水合性和良好的乳化稳定性，并且显示出良好的使用感（即， 粘合性，良好的相容性，无重触感和良好的铺展性），并且在化妆品组合物或皮肤外用剂组合物中掺入时，具有赋予保湿性和透湿性以及乳化稳定性的优点， 使用感好。

公开(公告)号：US06387359B1

公开(公告)日：2002-05-14

申请号：US09181611

申请日：1998-10-28

申请人： Hiroji Ishii ,  Masako Koyama ,  Tomomichi Ichikawa ,  Toshihiko Funakubo

发明人： Hiroji Ishii ,  Masako Koyama ,  Tomomichi Ichikawa ,  Toshihiko Funakubo

IPC分类号： A61K706

CPC分类号： A61K9/0014 ,  A61K8/44 ,  A61K47/183 ,  A61Q1/02 ,  A61Q1/06 ,  A61Q1/08 ,  A61Q1/10 ,  A61Q1/14 ,  A61Q5/00 ,  A61Q5/12 ,  A61Q9/02 ,  A61Q17/04 ,  A61Q19/00 ,  A61Q19/10 ,  C07C233/47 ,  C07C233/49 ,  C11D1/46

摘要： Herein are disclosed N-long chain acyl-neutral amino acid polyglycerin esters composed of a polyglycerin having a degree of glycerin polymerization of not smaller than 4 and an N-long chain acyl-neutral amino acid having an acyl group with from 6 to 22 carbon atoms and a nonionic surfactant composition comprising, as an active ingredient, at least one of said N-long chain acyl-neutral amino acid polyglycerin esters, which are favorably safe and which, when incorporated in cosmetic compositions or percutaneous preparations, are sensorially good.

摘要翻译： 本文公开了由甘油聚合度不小于4的聚甘油组成的N-长链酰基 - 中性氨基酸聚甘油酯和具有6-22个碳原子的酰基的N-长链酰基 - 中性氨基酸 原子和非离子表面活性剂组合物，其包含作为活性成分的至少一种所述N-长链酰基 - 中性氨基酸聚甘油酯，其有利地是安全的，并且当其掺入化妆品组合物或经皮制剂中时，其感觉良好。

公开(公告)号：US06528068B1

公开(公告)日：2003-03-04

申请号：US09219777

申请日：1998-12-23

申请人： Ryosuke Yumioka ,  Hiroji Ishii ,  Masako Koyama

发明人： Ryosuke Yumioka ,  Hiroji Ishii ,  Masako Koyama

IPC分类号： A61K600

CPC分类号： C07C233/49 ,  A61K8/44 ,  A61Q1/02 ,  A61Q1/06 ,  A61Q1/08 ,  A61Q1/10 ,  A61Q1/12 ,  A61Q1/14 ,  A61Q5/00 ,  A61Q5/02 ,  A61Q5/04 ,  A61Q5/06 ,  A61Q5/10 ,  A61Q5/12 ,  A61Q9/02 ,  A61Q17/04 ,  A61Q19/00 ,  A61Q19/10 ,  C07C233/47

摘要： An N-long-chain acyl neutral amino acid ester containing a straight-chain or branched-chain, saturated or unsaturated acyl group having from 6 to 22 carbon atoms, where the hydrocarbon group of the alcohol constituting the ester is a straight-chain or branched-chain, saturated or unsaturated hydrocarbon group having from 1 to 10 carbon atoms disclosed herein is an oily material suitable for cosmetic compositions, which provide an excellent feeling upon use and also an excellent hair conditioning effect to a cosmetic composition containing the same. An ultraviolet ray-absorbing composition containing the N-long-chain acyl neutral amino acid ester or/and an N-long-chain acyl acidic amino acid diester is provided, which also has excellent feel. An inorganic pigment composition containing the N-long-chain acyl neutral amino acid ester or/and the above-mentioned N-long-chain acyl acidic amino acid diester is also provided, which has excellent dispersion (stability) of the inorganic pigment, is less irritating to the skin, has excellent feel upon use and is not sticky.

摘要翻译： 含有具有6至22个碳原子的直链或支链，饱和或不饱和或不饱和的酰基的N-长链酰基中性氨基酸酯，其中构成酯的醇的烃基是直链或 本文公开的具有1至10个碳原子的支链，饱和或不饱和烃基是适用于化妆品组合物的油性材料，其在使用时提供优异的感觉，并且对含有其的化妆品组合物也具有优异的头发调理效果。 提供含有N-长链酰基中性氨基酸酯或/和N-长链酰基酸性氨基酸二酯的紫外线吸收组合物，其手感也良好。 还提供了含有N-长链酰基中性氨基酸酯或/和上述N-长链酰基酸性氨基酸二酯的无机颜料组合物，其具有优异的无机颜料的分散性（稳定性），是 对皮肤刺激性较小，使用感觉好，不粘。

公开(公告)号：US20110257236A1

公开(公告)日：2011-10-20

申请号：US13095265

申请日：2011-04-27

申请人： Masako KOYAMA ,  Momoko Kimura ,  Tetsuo Tanegawa

发明人： Masako KOYAMA ,  Momoko Kimura ,  Tetsuo Tanegawa

IPC分类号： A61K31/198 ,  A61P1/16 ,  A23J1/00 ,  A61K31/4172

CPC分类号： A61K9/141 ,  A61K31/198 ,  A61K2300/00

摘要： [Problem] A valine, isoleucine, leucine mixture which is excellent in the reduction of bitter taste and improved dissolution speed is provided.[Solving Means] The above problem is solved by a solid solution composed of three amino acids of valine, isoleucine, leucine, and a solid solution composed of these and at least one of acid selected from the group consisting of neutral aliphatic amino acid, neutral hydroxy amino acid, neutral acid amide amino acid, acidic amino acid, basic amino acid, hydroxy acid.

摘要翻译： [问题]提供了降低苦味和提高溶解速度优异的缬氨酸，异亮氨酸，亮氨酸混合物。 [解决方案]上述问题通过由缬氨酸，异亮氨酸，亮氨酸三种氨基酸组成的固溶体和由它们组成的固溶体和至少一种选自中性脂肪族氨基酸，中性 羟基氨基酸，中性酰胺氨基酸，酸性氨基酸，碱性氨基酸，羟基酸。

公开(公告)号：US5283297A

公开(公告)日：1994-02-01

申请号：US831579

申请日：1992-02-07

申请人： Yasuyoshi Miyachi ,  Nobuo Ito ,  Masako Koyama

发明人： Yasuyoshi Miyachi ,  Nobuo Ito ,  Masako Koyama

IPC分类号： C08G18/60 ,  A41G3/00 ,  A63H3/44 ,  C08G18/83 ,  C08G69/02 ,  C08G69/26 ,  D01F6/68 ,  D01F6/70 ,  D01F6/78

CPC分类号： A41G3/0083 ,  A63H3/44 ,  D01F6/68 ,  D01F6/78

摘要： An artificial hair made of a fibers comprising a poly-.alpha.-amino acid derivative insoluble to water and alcohols and represented by one of the following general formulae (1)-(4): ##STR1## providing that R in each of the above formula (1)-(4) is R.sup.a, R.sup.b and R.sup.c represented, respectively, by the following general formula (5), (6) or (7): ##STR2## or made or polyamino acid urethane fiber comprising a copolymer of an amino acid N-carboxy anhydride and a polyurethane, in which the copolymer is subjected to an amidation reaction with an organic diamine and an organic amine having amino groups and mercapto groups or disulfide groups and to shaping into a fibrous form.The artificial hair has a dyeability, shape retainability, natural and soft and flexible feeling, excellent tough and brushing property, as well as has natural color and gloss and toughness like that natural protein fiber.

摘要翻译： 一种由纤维构成的人造毛发，其包含不溶于水和醇的聚（α） - 氨基酸衍生物，并由以下通式（1） - （4）之一表示：（*化学结构*）（1）（ *化学结构*）（2）（*化学结构*）（3）或（*化学结构*）（4）使上述式（1） - （4）中的R为Ra，Rb和Rc 分别由以下通式（5），（6）或（7）表示：（-CH2）kCONR1（CH2）1NR2R3，（5）（-CH2）kCONR1（CH2）1SR2，（6）（ - kCOOR'，H，R'OR-CH2CH2SMe，（7）或包含氨基酸N-羧酸酐和聚氨酯的共聚物的制备或聚氨基酸聚氨酯纤维，其中共聚物与有机二胺进行酰胺化反应 和具有氨基和巯基或二硫键的有机胺，并成型为纤维状。 人造头发具有可染性，形状保持性，自然柔软柔软的感觉，优异的韧性和刷牙性，以及具有天然色素和光泽和韧性的天然蛋白纤维。