公开(公告)号：US20180318324A1

公开(公告)日：2018-11-08

申请号：US15773967

申请日：2016-11-03

申请人： Prescient Pharma LLC

发明人： Pavel Idelevich ,  Anna Idelevich

IPC分类号： A61K31/704 ,  A61P9/10 ,  A61P9/12 ,  A61P19/10 ,  A61P25/28 ,  A61P35/00 ,  A61P37/00

CPC分类号： A61K31/704 ,  A61K8/19 ,  A61K8/20 ,  A61K8/37 ,  A61K8/63 ,  A61K31/191 ,  A61K31/194 ,  A61K31/203 ,  A61K33/00 ,  A61K33/14 ,  A61K2300/00 ,  A61P9/10 ,  A61P9/12 ,  A61P19/10 ,  A61P25/28 ,  A61P35/00 ,  A61P37/00 ,  A61Q19/08

摘要： The invention generally relates to anti-aging compositions and methods for using the anti-aging compositions. In one aspect, the invention provides a method for preventing cellular aging in a cell of a subject, the method comprising the step of providing to the cell an effective amount of at least one lithium compound or a pharmaceutically acceptable salt thereof, and an effective amount of at least one glycyrrhizie triterpenoid compound or a pharmaceutically acceptable salt thereof, thereby preventing the cell from aging. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.

公开(公告)号：US20180250215A1

公开(公告)日：2018-09-06

申请号：US15970339

申请日：2018-05-03

申请人： Edward Dunne Corboy, JR.

发明人： Edward Dunne Corboy, JR.

IPC分类号： A61K8/63 ,  A61K31/568 ,  A61K45/06 ,  A61K8/42 ,  A61K8/49 ,  A61K31/5575 ,  A61Q7/00

CPC分类号： A61K8/63 ,  A61K8/42 ,  A61K8/4953 ,  A61K31/5575 ,  A61K31/568 ,  A61K45/06 ,  A61Q7/00 ,  A61K2300/00

摘要： The present invention relates to the composition and method of use for the topical application of the potent androgen hormone dihydrotestosterone (DHT), used alone or in fixed combination with other hair growth medications; including other androgens, bimatoprost, other prostamides, prostaglandins, minoxidil or apocrine hair growth factors to promote and enhance hair growth of terminal mustache hair, beard hair, also chest hair, and other male androgen sensitive or dependent hair growth in humans or animals.

公开(公告)号：US09913789B2

公开(公告)日：2018-03-13

申请号：US14908195

申请日：2014-07-01

申请人： Evonik Degussa GmbH

发明人： Tim Köhler ,  Mike Farwick ,  Matthias Mentel ,  Peter Lersch

IPC分类号： A61K8/41 ,  A61K31/133 ,  A61K31/191 ,  A61K31/198 ,  A61K31/201 ,  A61K31/205 ,  A61K31/4168 ,  A61K31/4188 ,  A61K31/506 ,  A61K31/522 ,  A61K8/36 ,  A61K8/44 ,  A61K8/49 ,  A61K8/63 ,  A61Q5/12 ,  A61Q7/00 ,  A61K8/67

CPC分类号： A61K8/41 ,  A61K8/361 ,  A61K8/44 ,  A61K8/4946 ,  A61K8/4953 ,  A61K8/63 ,  A61K8/673 ,  A61K31/133 ,  A61K31/191 ,  A61K31/198 ,  A61K31/201 ,  A61K31/205 ,  A61K31/4168 ,  A61K31/4188 ,  A61K31/506 ,  A61K31/522 ,  A61Q5/12 ,  A61Q7/00 ,  A61K2300/00

摘要： The present invention relates to formulations comprising A) sphinganine and B) at least one active ingredient selected from the group creatine, creatinine, caffeine, carnitine, biotin, arjunolic acid, xymenynic acid, minoxidil, arginine and derivatives thereof.

公开(公告)号：US09884119B2

公开(公告)日：2018-02-06

申请号：US13505473

申请日：2010-11-03

申请人： Anders Carlsson ,  Jan Holmback

发明人： Anders Carlsson ,  Jan Holmback

IPC分类号： C09D7/12 ,  A61K47/24 ,  A01N25/02 ,  A61K8/34 ,  A61K8/37 ,  A61K8/55 ,  A61K8/63 ,  A61K8/891 ,  A61K9/08 ,  A61K47/14 ,  A61Q7/00 ,  A61Q19/00 ,  A01N37/18 ,  A61K8/49 ,  A61K8/89 ,  A61K9/00 ,  A61K31/167 ,  A61K31/245 ,  A61K31/4174 ,  A61K31/573 ,  A61K38/13 ,  A61K47/10 ,  A61K47/34 ,  A61Q17/02

CPC分类号： A61K47/24 ,  A01N25/02 ,  A01N37/18 ,  A61K8/34 ,  A61K8/342 ,  A61K8/37 ,  A61K8/4953 ,  A61K8/553 ,  A61K8/63 ,  A61K8/89 ,  A61K8/891 ,  A61K9/0014 ,  A61K9/08 ,  A61K31/167 ,  A61K31/245 ,  A61K31/4174 ,  A61K31/573 ,  A61K38/13 ,  A61K47/10 ,  A61K47/14 ,  A61K47/34 ,  A61Q7/00 ,  A61Q17/02 ,  A61Q19/00

摘要： A lipid layer forming composition comprises a volatile silicone oil of a boiling point above 180° C., a polar lipid, optionally a C2-C4 aliphatic alcohol, optionally a pharmacologically or cosmetically active agent or a protective agent. The lipid layer forming composition can be applied to a biological surface by spraying, dipping or brushing to form a stable polar lipid layer on the surface.

公开(公告)号：US20180015145A1

公开(公告)日：2018-01-18

申请号：US15664548

申请日：2017-07-31

申请人： Centro de Ingeniería Genética y Biotecnología ,  Consejo Superior de Investigaciones Científicas

发明人： Héctor Jesús Santana Milián ,  Leonor Ventosa Rull ,  Eduardo Martínez Díaz ,  Jorge Amador Berlanga Acosta ,  Ingrid Cabrera Puig ,  Jaume Veciana Miró

IPC分类号： A61K38/18 ,  A61K9/127 ,  A61K8/41 ,  A61L26/00 ,  A61K8/63 ,  A61K47/18 ,  A61K8/14 ,  A61K9/00 ,  A61K8/64 ,  A61Q19/08 ,  A61K47/28

CPC分类号： A61K38/1808 ,  A61K8/14 ,  A61K8/416 ,  A61K8/63 ,  A61K8/64 ,  A61K9/0014 ,  A61K9/127 ,  A61K9/1271 ,  A61K9/1277 ,  A61K47/186 ,  A61K47/28 ,  A61K2800/805 ,  A61L26/0066 ,  A61L2300/414 ,  A61Q19/08

摘要： The invention relates to vesicles comprising Epidermal Growth Factor (EGF), a cationic surfactant and cholesterol or derivatives thereof. The invention also discloses a procedure for their preparation, based on compressed fluid technology (CFs). The vesicles of the invention are useful in the manufacture of drugs and cosmetics and in tissue engineering.

公开(公告)号：US20170367960A1

公开(公告)日：2017-12-28

申请号：US15696644

申请日：2017-09-06

申请人： The Nisshin OilliO Group, Ltd.

发明人： Aki Nomura ,  Hisanori Kachi ,  Makoto Matsuzawa ,  Hiromu Tokura ,  Minaho Komori

IPC分类号： A61K8/73 ,  A61K8/81 ,  A61K8/92 ,  A61K8/86 ,  A61K8/31 ,  A61K8/63 ,  A61K8/60 ,  A61K8/46 ,  A61K8/37 ,  A61K8/34 ,  A61Q19/00 ,  A61K8/06

CPC分类号： A61K8/73 ,  A61K8/062 ,  A61K8/31 ,  A61K8/345 ,  A61K8/37 ,  A61K8/463 ,  A61K8/60 ,  A61K8/63 ,  A61K8/731 ,  A61K8/733 ,  A61K8/81 ,  A61K8/8111 ,  A61K8/8129 ,  A61K8/8147 ,  A61K8/8152 ,  A61K8/86 ,  A61K8/922 ,  A61K8/925 ,  A61K2800/54 ,  A61Q19/00

摘要： A water-based cosmetic including:agar having a weight average molecular weight of 10,000 to 60,000 (component (A));xanthan gum (component (B)); anda water-soluble polymer excluding the component (A) or (B) (component (C)).

公开(公告)号：US20170333337A1

公开(公告)日：2017-11-23

申请号：US15534243

申请日：2015-12-07

申请人： Michel FREY

发明人： Michel FREY

IPC分类号： A61K8/9789 ,  A23L33/10 ,  A61K8/67 ,  A61K8/63 ,  A61K8/60 ,  A61K8/55 ,  A61K8/19 ,  A61K8/11 ,  A61K8/04 ,  A61K8/02 ,  A61K8/9794 ,  A23L33/15 ,  A23L33/16 ,  A23L33/105 ,  A61Q19/08

CPC分类号： A61K8/9789 ,  A23L33/10 ,  A23L33/105 ,  A23L33/15 ,  A23L33/16 ,  A23L33/18 ,  A23V2002/00 ,  A61K8/0229 ,  A61K8/042 ,  A61K8/11 ,  A61K8/19 ,  A61K8/55 ,  A61K8/606 ,  A61K8/63 ,  A61K8/673 ,  A61K8/676 ,  A61K8/97 ,  A61K8/9794 ,  A61K31/7076 ,  A61K36/31 ,  A61K36/481 ,  A61K36/736 ,  A61K36/8945 ,  A61Q19/08 ,  A61K2300/00

摘要： The invention relates to a composition for slowing cellular ageing which comprises at least: S-Adenosyl-methionine; an extract of at least one adaptogenic plant selected among plants belonging to the Astragalus, Dioscorea, Schisandra, Panax, Eleuterococcus, Rosmarinus, Pfaffia, Morinda, Cordyceps or Lepidium genera; a vitamin selected among the B vitamins, vitamin C, or a mixture thereof; except for compositions comprising 7-keto-DHEA and an extract of one or more adaptogenic plants belonging to the Dioscorea or Lepidium genera. A liquid or solid food supplement can be characterised in that it comprises the composition. A dermatologically acceptable composition can be characterised in that it comprises at least 10 wt % of the composition.

公开(公告)号：US09770419B2

公开(公告)日：2017-09-26

申请号：US13953888

申请日：2013-07-30

申请人： Shaker A. Mousa ,  Abdulqader Al Haider ,  Abdelgalil Abdelgader ,  Abdullah M. Aldahmash ,  Abdulkareem Almomen

发明人： Shaker A. Mousa ,  Abdulqader Al Haider ,  Abdelgalil Abdelgader ,  Abdullah M. Aldahmash ,  Abdulkareem Almomen

IPC分类号： A61K47/42 ,  A61K31/726 ,  A61K31/728 ,  A61K31/738 ,  A23C9/152 ,  A23P10/30 ,  A23L33/19 ,  A61K9/48 ,  A61K31/337 ,  A61K31/704 ,  A61K31/12 ,  A61K31/727 ,  A61K47/48 ,  A61K9/51 ,  A23G9/00 ,  A61K8/63 ,  A61K8/64 ,  A61Q11/00 ,  A61K8/73 ,  A61K8/02 ,  A61K38/00

CPC分类号： A61K9/4866 ,  A23C9/152 ,  A23C2260/152 ,  A23G9/00 ,  A23L33/19 ,  A23P10/30 ,  A23V2002/00 ,  A61K8/0283 ,  A61K8/63 ,  A61K8/64 ,  A61K8/73 ,  A61K8/736 ,  A61K9/5153 ,  A61K9/5169 ,  A61K31/12 ,  A61K31/337 ,  A61K31/704 ,  A61K31/726 ,  A61K31/727 ,  A61K31/728 ,  A61K31/738 ,  A61K38/00 ,  A61K47/42 ,  A61K47/644 ,  A61K47/68 ,  A61K47/6929 ,  A61K47/6937 ,  A61K2800/413 ,  A61Q11/00 ,  A23V2200/25 ,  A23V2250/54246 ,  A23V2250/54248

摘要： The present invention provides a composition, a dairy product, and a method for treating a disorder in a subject. The composition includes (i) polymeric nanoparticles and (ii) camel derived glycosaminoglycans (GAG)s ionic complex encapsulated into the nanoparticles, at least one active ingredient encapsulated into the nanoparticles, or combinations thereof. The nanoparticles are lactoferrin nanoparticles including camel derived lactoferrin, casein nanoparticles including camel derived casein, or combinations thereof. The dairy product includes ice cream or frozen yogurt, wherein the ice cream or frozen yogurt includes the composition and is derived from camel milk or other species of milk. The method for treating a disorder in a subject includes administering a therapeutic dose of the composition to the subject.

公开(公告)号：US09738682B2

公开(公告)日：2017-08-22

申请号：US15124273

申请日：2015-03-10

申请人： GIULIANI S.P.A.

发明人： Giammaria Giuliani ,  Anna Benedusi ,  Barbara Marzani ,  Sergio Baroni ,  Elena Pini ,  Raffaella Gandolfi

IPC分类号： C07J9/00 ,  A61K8/36 ,  A61Q5/00 ,  A61K45/06 ,  C07C69/587 ,  C07C279/14 ,  C07C57/03 ,  A61K8/37 ,  A61K8/44 ,  A61Q1/14 ,  A61K8/63 ,  A61Q7/00 ,  A61Q17/04 ,  A61Q19/00

CPC分类号： C07J9/00 ,  A61K8/361 ,  A61K8/37 ,  A61K8/375 ,  A61K8/44 ,  A61K8/63 ,  A61K45/06 ,  A61K2800/10 ,  A61Q1/14 ,  A61Q5/00 ,  A61Q7/00 ,  A61Q17/04 ,  A61Q19/00 ,  A61Q19/004 ,  A61Q19/007 ,  C07C57/03 ,  C07C69/587 ,  C07C279/14

摘要： The invention relates to 2,4,6-octatrienoic acid derivative compounds having general formula (I) (CH3—CH═CH—CH═CH—CH═CH—CO—O—)n—R (I) consisting of esters wherein n=1, 2, 3 and wherein R is selected from alkyl, aryl or cycloalkyl of a polyol, phenol or phenolic acid; or consisting of a salt wherein n=1 and R=arginine, as active ingredients in a pharmaceutical or cosmetic composition having a combined antioxidant activity against free radicals together with an anti-inflammatory action.

公开(公告)号：US20170196895A1

公开(公告)日：2017-07-13

申请号：US15461086

申请日：2017-03-16

申请人： SHAPERON Inc.

发明人： Seung Yong SEONG ,  Youn Hee KIM

IPC分类号： A61K31/575 ,  A61K9/06 ,  A61K9/14 ,  A61K9/20 ,  C11D13/10 ,  A61K9/16 ,  A61K9/00 ,  A61K9/08 ,  A61K8/63 ,  C11D13/26 ,  A61K31/728 ,  A61K9/48

CPC分类号： A61K31/575 ,  A61K8/63 ,  A61K9/0019 ,  A61Q19/00 ,  C11D13/10 ,  C11D13/26

摘要： The present invention is about a pharmaceutical composition, an oral preparation, and an injection preparation containing a G protein-coupled Receptor19 (GPCR19) agonist, specifically sodium taurodeoxycholate(HY2191) and its derivative, as an active ingredient for preventing or treating allergic skin diseases. The present invention is also about an external preparation and a cosmetic composition containing said pharmaceutical composition for preventing and improving allergic skin diseases. The said pharmaceutical composition shows an excellent efficacy in treating and improving allergic dermatitis compared with the steroid ointments or immunosuppressive ointments currently used. The said pharmaceutical composition reduces the level of serum IgE, which is a major factor causing allergic dermatitis, increases TH1 cytokine alleviating allergic dermatitis and reduces TH2 cytokine that exacerbates allergic dermatitis. The said pharmaceutical composition also reduces infiltration of a mast cell, eosinophil, and neutrophil in dermis and ameliorates clinical symptoms such as erythema, hemorrhage, edema, excoriation, erosion, scaling and dryness. Thus, the said pharmaceutical composition can be used to prevent and treat allergic skin diseases.