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公开(公告)号：US08101760B2
公开(公告)日：2012-01-24
申请号：US12305295
申请日：2007-07-12
Applicant: Matthew William Carson , Michael Joseph Coghlan
Inventor： Matthew William Carson , Michael Joseph Coghlan
IPC: C07D455/03 , C07D313/10 , A61K31/4353
CPC classification number: C07D491/044
Abstract: The present invention provides Compound (I): Compound (I) or a pharmaceutically acceptable salt thereof; pharmaceutical compositions comprising Compound (I) in combination with one or more pharmaceutically acceptable carriers, excipients, or diluents; and methods for the treatment of inflammatory and immune disorders comprising administering to a patient in need thereof an effective amount of Compound (I) or a pharmaceutically acceptable salt thereof.
Abstract translation: 本发明提供化合物（I）：化合物（I）或其药学上可接受的盐; 包含化合物（I）与一种或多种药学上可接受的载体，赋形剂或稀释剂组合的药物组合物; 以及用于治疗炎症和免疫疾病的方法，包括向有需要的患者施用有效量的化合物（I）或其药学上可接受的盐。
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公开(公告)号：US20100069425A1
公开(公告)日：2010-03-18
申请号：US12305295
申请日：2007-07-12
Applicant: Matthew William Carson , Michael Joseph Coghlan
Inventor： Matthew William Carson , Michael Joseph Coghlan
IPC: A61K31/4353 , C07D221/00 , A61P37/02
CPC classification number: C07D491/044
Abstract: The present invention provides Compound (I): Compound (I) or a pharmaceutically acceptable salt thereof; pharmaceutical compositions comprising Compound (I) in combination with one or more pharmaceutically acceptable carriers, excipients, or diluents; and methods for the treatment of inflammatory and immune disorders comprising administering to a patient in need thereof an effective amount of Compound (I) or a pharmaceutically acceptable salt thereof.
Abstract translation: 本发明提供化合物（I）：化合物（I）或其药学上可接受的盐; 包含化合物（I）与一种或多种药学上可接受的载体，赋形剂或稀释剂组合的药物组合物; 以及用于治疗炎症和免疫疾病的方法，包括向有需要的患者施用有效量的化合物（I）或其药学上可接受的盐。
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![(E)-N-{3-[1-(8-fluoro-11H-10-OXA-1-AZA-dibenzo [A,D] cyclohepten-5ylidene)-propyl]-phenyl}-methanesulfonamide as glucocorticoid receptor modulator for the treatment of rheumatoid arthritis](/abs-image/US/2012/01/24/US08101761B2/abs.jpg.150x150.jpg)
3.发明授权(E)-N-{3-[1-(8-fluoro-11H-10-OXA-1-AZA-dibenzo [A,D] cyclohepten-5ylidene)-propyl]-phenyl}-methanesulfonamide as glucocorticoid receptor modulator for the treatment of rheumatoid arthritis 失效（E）-N- {3- [1-（8-氟-11H-10-OXA-1-AZA-二苯并[A，D]环庚烯-5-亚基） - 丙基] - 苯基} - 甲磺酰胺，为糖皮质激素受体调节剂 治疗类风湿性关节炎公开(公告)号：US08101761B2
公开(公告)日：2012-01-24
申请号：US12810886
申请日：2009-01-08
Applicant: Matthew William Carson , Michael Joseph Coghlan
Inventor： Matthew William Carson , Michael Joseph Coghlan
IPC: C07D455/03 , C07D313/10 , A61K31/4353
CPC classification number: C07D491/044
Abstract: The present invention provides Compound (I) or a pharmaceutically acceptable salt thereof; pharmaceutical compositions comprising Compound (I) in combination with one or more pharmaceutically acceptable carriers, excipients, or diluents; and discloses methods for the treatment of inflammatory and immune disorders comprising administering to a patient in need thereof an effective amount of Compound (I) or a pharmaceutically acceptable salt thereof.
Abstract translation: 本发明提供化合物（I）或其药学上可接受的盐; 包含化合物（I）与一种或多种药学上可接受的载体，赋形剂或稀释剂组合的药物组合物; 并公开了用于治疗炎症和免疫疾病的方法，包括向有需要的患者施用有效量的化合物（I）或其药学上可接受的盐。
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4.发明申请(E)-N--METHANESULFONAMIDE AS GLUCOCORTICOID RECEPTOR MODULATOR FOR THE TREATMENT OF RHEUMATOID ARTHRITIS 失效（E）-N-甲磺酰胺作为治疗恶性肿瘤的葡萄糖激素受体调节剂公开(公告)号：US20100280062A1
公开(公告)日：2010-11-04
申请号：US12810886
申请日：2009-01-08
Applicant: Matthew William Carson , Michael Joseph Coghlan
Inventor： Matthew William Carson , Michael Joseph Coghlan
IPC: A61K31/4353 , C07D491/044 , A61P29/00 , A61P11/06 , A61P11/00 , A61P1/00
CPC classification number: C07D491/044
Abstract: The present invention provides Compound (I) or a pharmaceutically acceptable salt thereof; pharmaceutical compositions comprising Compound (I) in combination with one or more pharmaceutically acceptable carriers, excipients, or diluents; and discloses methods for the treatment of inflammatory and immune disorders comprising administering to a patient in need thereof an effective amount of Compound (I) or a pharmaceutically acceptable salt thereof.
Abstract translation: 本发明提供化合物（I）或其药学上可接受的盐; 包含化合物（I）与一种或多种药学上可接受的载体，赋形剂或稀释剂组合的药物组合物; 并公开了用于治疗炎症和免疫疾病的方法，包括向有需要的患者施用有效量的化合物（I）或其药学上可接受的盐。
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