Encapsulation of active ingredients
    2.
    发明授权
    Encapsulation of active ingredients 有权
    活性成分的包封

    公开(公告)号:US06482433B1

    公开(公告)日:2002-11-19

    申请号:US09606518

    申请日:2000-06-29

    Abstract: A process for preparing free-flowing and, during handling, dust-free microparticles. The particles are at least 90% by weight, have a diameter of 100-400 &mgr;m, and contain one or more active ingredients in a glassy matrix. Generally, the process of the invention comprises the steps of (1) preparing an aqueous solution of the matrix materials, (2) mixing the flavor into the aqueous solution with stirring to form an emulsion or suspension, (3) spraying the emulsion in a spray drying tower under a supply of hot air to quickly create a semi-solid skin allowing outtake of moisture (water), and (4) subsequently subjecting the resulting particles to continued drying at lower temperatures in a fluid bed.

    Abstract translation: 一种制备自由流动和处理过程中无尘的微粒的方法。 颗粒至少为90重量%,直径为100-400μm,并且在玻璃质基质中含有一种或多种活性成分。 通常,本发明的方法包括以下步骤:(1)制备基质材料的水溶液,(2)在搅拌下将风味剂混合到水溶液中以形成乳液或悬浮液,(3)将乳液喷雾在 喷雾干燥塔在热空气供应下快速产生半固体皮肤,允许除去水分(水),和(4)随后使所得颗粒在流化床中在较低温度下继续干燥。

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