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公开(公告)号:US6056949A
公开(公告)日:2000-05-02
申请号:US51343
申请日:1998-04-06
Applicant: Heini Menzi , Matthias Perren , Rudolf Ringgenberg
Inventor: Heini Menzi , Matthias Perren , Rudolf Ringgenberg
CPC classification number: A61Q13/00 , A23F3/405 , A23L2/39 , A23L2/56 , A23L27/72 , A23L33/15 , A23L7/196 , A23P10/22 , A23P10/30 , A23P10/35 , A61K8/025 , A61Q11/00
Abstract: The present invention relates to a process for the preparation of spherical or substantially spherical, practically dust-free aromatic and odoriferous granulated material which is free-flowing, mechanically stable and has a narrow grain-size distribution.
Abstract translation: PCT No.PCT / CH96 / 00373 Sec。 371日期:1998年4月6日 102(e)1998年4月6日PCT PCT 1996年10月23日PCT公布。 公开号WO97 / 16078 日期1997年5月9日本发明涉及一种制备球形或基本上球形,实际上无尘的芳香和有气味的造粒材料的方法,其自由流动,机械稳定并且具有窄的粒度分布。
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公开(公告)号:US06482433B1
公开(公告)日:2002-11-19
申请号:US09606518
申请日:2000-06-29
Applicant: Kris Bart DeRoos , Matthias Perren , Gregory Alan Sherman
Inventor: Kris Bart DeRoos , Matthias Perren , Gregory Alan Sherman
IPC: A61K914
CPC classification number: B01J13/043 , A23L27/70 , A23L27/80 , A23P10/30 , A23P10/40 , Y10S514/951
Abstract: A process for preparing free-flowing and, during handling, dust-free microparticles. The particles are at least 90% by weight, have a diameter of 100-400 &mgr;m, and contain one or more active ingredients in a glassy matrix. Generally, the process of the invention comprises the steps of (1) preparing an aqueous solution of the matrix materials, (2) mixing the flavor into the aqueous solution with stirring to form an emulsion or suspension, (3) spraying the emulsion in a spray drying tower under a supply of hot air to quickly create a semi-solid skin allowing outtake of moisture (water), and (4) subsequently subjecting the resulting particles to continued drying at lower temperatures in a fluid bed.
Abstract translation: 一种制备自由流动和处理过程中无尘的微粒的方法。 颗粒至少为90重量%,直径为100-400μm,并且在玻璃质基质中含有一种或多种活性成分。 通常,本发明的方法包括以下步骤:(1)制备基质材料的水溶液,(2)在搅拌下将风味剂混合到水溶液中以形成乳液或悬浮液,(3)将乳液喷雾在 喷雾干燥塔在热空气供应下快速产生半固体皮肤,允许除去水分(水),和(4)随后使所得颗粒在流化床中在较低温度下继续干燥。
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