公开(公告)号：US09771416B2

公开(公告)日：2017-09-26

申请号：US13881398

申请日：2011-10-25

申请人： Greg Hussack ,  Mehdi Nath Arbabi-Ghahroudi ,  Roger Mackenzie ,  Jamshid Tanha

发明人： Greg Hussack ,  Mehdi Nath Arbabi-Ghahroudi ,  Roger Mackenzie ,  Jamshid Tanha

IPC分类号： C07K16/12 ,  G01N33/569

CPC分类号： C07K16/1282 ,  C07K2317/22 ,  C07K2317/35 ,  C07K2317/569 ,  C07K2317/76 ,  C07K2317/92 ,  C07K2317/94 ,  G01N33/56911 ,  G01N2333/33

摘要： The present invention is directed to Clostridium difficile toxin-specific antibodies, compositions, and uses thereof. The anti-toxin antibodies may be specific for either TcdA or TcdB. The invention also includes methods of treating a Clostridium difficile infection, methods of capturing Clostridium difficile toxins, and methods of detecting Clostridium difficile toxins.

公开(公告)号：US20130230537A1

公开(公告)日：2013-09-05

申请号：US13881398

申请日：2011-10-25

申请人： Greg Hussack ,  Mehdi Nath Arbabi-Ghahroudi ,  Roger Mackenzie ,  Jamshid Tanha

发明人： Greg Hussack ,  Mehdi Nath Arbabi-Ghahroudi ,  Roger Mackenzie ,  Jamshid Tanha

IPC分类号： C07K16/12

CPC分类号： C07K16/1282 ,  C07K2317/22 ,  C07K2317/35 ,  C07K2317/569 ,  C07K2317/76 ,  C07K2317/92 ,  C07K2317/94 ,  G01N33/56911 ,  G01N2333/33

摘要： The present invention is directed to Clostridium difficile toxin-specific antibodies, compositions, and uses thereof. The anti-toxin antibodies may be specific for either TcdA or TcdB. The invention also includes methods of treating a Clostridium difficile infection, methods of capturing Clostridium difficile toxins, and methods of detecting Clostridium difficile toxins.

摘要翻译： 本发明涉及艰难梭菌毒素特异性抗体，组合物及其应用。 抗毒素抗体可能对TcdA或TcdB是特异性的。 本发明还包括治疗艰难梭菌感染的方法，捕获艰难梭菌毒素的方法，以及检测艰难梭菌毒素的方法。