Enkurin and uses thereof
    1.
    发明授权
    Enkurin and uses thereof 失效
    Enkurin及其用途

    公开(公告)号:US06991909B2

    公开(公告)日:2006-01-31

    申请号:US10375693

    申请日:2003-02-25

    IPC分类号: G01N33/53 G01N33/537

    摘要: A novel protein, enkurin, that is preferentially expressed in sperm has been discovered. Enkurin binds to TRPCs including TRPC2-S, a protein encoded by TRPC2 that is not predicted to be a calcium channel subunit. The invention includes methods of identifying compounds that affect enkurin expression or activity, and are useful, e.g., for contraception and treatment of infertility.

    摘要翻译: 已经发现了优先在精子中表达的新蛋白质enkurin。 Enkurin结合TRPC,包括TRPC2-S,由TRPC2编码的蛋白质,其不被预测为钙通道亚基。 本发明包括鉴定影响enkurin表达或活性的化合物的方法,并且可用于例如避孕和治疗不育症。